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Butamyrate

Product Name
Butamyrate
CAS No.
18109-80-3
Chemical Name
Butamyrate
Synonyms
Brospamin;Butamirate;Butamirato;Butamyrate;Butamiratum;Butamirate (Base);Butamirate [inn:ban];Butamyrate USP/EP/BP;Butamiratum [inn-latin];Butamirato [inn-spanish]
CBNumber
CB6875075
Molecular Formula
C18H29NO3
Formula Weight
307.431
MOL File
18109-80-3.mol
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Butamyrate Property

Melting point:
<25 °C
Boiling point:
bp1 140-155°
Density 
1.007±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
9.68±0.25(Predicted)
form 
Oil
color 
Clear Colourless to Dark Yellow
LogP
3.39
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B699860
Product name
Butamirate
Packaging
10mg
Price
$95
Updated
2021/12/16
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Butamyrate Chemical Properties,Usage,Production

Originator

Sinecod,Hommel,Switz.,1967

Uses

Antitussive.

Definition

ChEBI: Butamirate is an alkylbenzene.

Manufacturing Process

18.2 grams of α-phenylbutyric acid chloride are dissolved in 25 ml of toluene. To this solution, there is slowly added a solution of 16.1 grams of diethylaminoethoxyethanol in 25 ml of toluene, the reaction mixture thereby becoming hot. It is then heated for 8 hr under reflux. The reaction mixture, after cooling, is carefully poured onto 75 grams of ice and made alkaline with dilute ammonia. After thorough shaking of the solution, the toluene layer is removed and washed until neutral with water. The toluene solution is treated with carbon and dried over sodium sulfate. The toluene is distilled off from the filtered solution.
The residue is α-phenylbutyric acid diethylaminoethoxyethyl ester. The basic ester is purified by distillation in a high vacuum. 10 grams of ester are added to a solution of 7 grams of citric acid in 30 ml of warm acetone. After standing for some time, the citrate of the ester crystallizes out. After suction filtration and washing with acetone the ester citrate is recrystallized from acetone. The melting point of the citrate is 75°C.

Therapeutic Function

Antitussive

Butamyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Butamyrate Suppliers

Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
Shanghai CR Corporation Limited
Tel
021-80270511; 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
10044
Advantage
58
CR Corporation Limited
Tel
+8613062833949
Email
fred.wen@crcorporation.cn
Country
China
ProdList
8647
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22785
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
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58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10001
Advantage
58
Wuhan Beileye Biomedical Technology Co., Ltd.
Tel
18086118078
Email
2696158611@qq.com
Country
China
ProdList
4277
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shaanxi kelkai Pharmaceutical Technology Co., Ltd
Tel
029-029-2148545164 17392779578
Email
2148545164@qq.com
Country
China
ProdList
4818
Advantage
58
Xi'an Lechun Chemical Co., Ltd
Tel
029-15596886083 15596886083
Email
739383595@qq.com
Country
China
ProdList
3901
Advantage
58
Nanjing Ningjitong Pharmaceutical Biotechnology Co., Ltd
Tel
0-19710401727 19710401727
Email
3805829626@QQ.COM
Country
China
ProdList
500
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
29971
Advantage
58
Guangzhou PI PI Biotech Inc
Tel
020-81716320 +86-13602409664
Fax
020-81716319
Email
Sales@pipitech.com
Country
China
ProdList
3633
Advantage
55
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
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56
Shanghai New Union Textra Import & Export Co., Ltd
Tel
--
Fax
--
Email
zhou@pharmchemical.com
Country
China
ProdList
2748
Advantage
60
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View Lastest Price from Butamyrate manufacturers

Dideu Industries Group Limited
Product
Butamyrate 18109-80-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100Tons min
Release date
2021-06-10

18109-80-3, ButamyrateRelated Search:


  • 2-[2-(diethylamino)ethoxy]ethyl 2-phenylbutanoate
  • 2-Phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester
  • Benzeneacetic acid, alpha-ethyl-, 2-(2-(diethylamino)ethoxy)ethyl ester
  • Brospamin
  • Butamirate [inn:ban]
  • Butamirato
  • Butamirato [inn-spanish]
  • Butamiratum
  • Butamiratum [inn-latin]
  • Butamirate (Base)
  • Butamirate
  • Butamyrate
  • Benzeneacetic acid, α-ethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
  • Butamyrate USP/EP/BP
  • 18109-80-3