Butamyrate
- Product Name
- Butamyrate
- CAS No.
- 18109-80-3
- Chemical Name
- Butamyrate
- Synonyms
- Brospamin;Butamirate;Butamirato;Butamyrate;Butamiratum;Butamirate (Base);Butamirate [inn:ban];Butamyrate USP/EP/BP;Butamiratum [inn-latin];Butamirato [inn-spanish]
- CBNumber
- CB6875075
- Molecular Formula
- C18H29NO3
- Formula Weight
- 307.431
- MOL File
- 18109-80-3.mol
Butamyrate Property
- Melting point:
- <25 °C
- Boiling point:
- bp1 140-155°
- Density
- 1.007±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 9.68±0.25(Predicted)
- form
- Oil
- color
- Clear Colourless to Dark Yellow
- LogP
- 3.39
N-Bromosuccinimide Price
- Product number
- B699860
- Product name
- Butamirate
- Packaging
- 10mg
- Price
- $95
- Updated
- 2021/12/16
Butamyrate Chemical Properties,Usage,Production
Originator
Sinecod,Hommel,Switz.,1967
Uses
Antitussive.
Definition
ChEBI: Butamirate is an alkylbenzene.
Manufacturing Process
18.2 grams of α-phenylbutyric acid chloride are dissolved in 25 ml of toluene.
To this solution, there is slowly added a solution of 16.1 grams of
diethylaminoethoxyethanol in 25 ml of toluene, the reaction mixture thereby
becoming hot. It is then heated for 8 hr under reflux. The reaction mixture,
after cooling, is carefully poured onto 75 grams of ice and made alkaline with
dilute ammonia. After thorough shaking of the solution, the toluene layer is
removed and washed until neutral with water. The toluene solution is treated
with carbon and dried over sodium sulfate. The toluene is distilled off from the
filtered solution.
The residue is α-phenylbutyric acid diethylaminoethoxyethyl ester. The basic
ester is purified by distillation in a high vacuum. 10 grams of ester are added
to a solution of 7 grams of citric acid in 30 ml of warm acetone. After standing
for some time, the citrate of the ester crystallizes out. After suction filtration and washing with acetone the ester citrate is recrystallized from acetone. The
melting point of the citrate is 75°C.
Therapeutic Function
Antitussive
Butamyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Butamyrate Suppliers
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- Country
- India
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- Advantage
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View Lastest Price from Butamyrate manufacturers
- Product
- Butamyrate 18109-80-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100Tons min
- Release date
- 2021-06-10