Mechanism of action Structure
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IGF-1 LR3

Mechanism of action Structure
Product Name
IGF-1 LR3
CAS No.
946870-92-4
Chemical Name
IGF-1 LR3
Synonyms
CL281;LR3-IGF1;IDF-1 LR3;IGF LR3-1;IGF-1 LR3;IGF-1Lr3 Igtropin;LR3-IGF1 (100mcg/vial;LR3-IGF1, LR3-IGF-1, IGF1;Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1
CBNumber
CB6947862
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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IGF-1 LR3 Chemical Properties,Usage,Production

Mechanism of action

IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.IGF-1 LR3 obstructs the movement of glucose into the body’s cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a life in the body for about 20-30 hours and therefore enhance the growth amount of muscle for a whole day.

Structure

IGF-1 LR3 is a recombinant synthetic growth factor of ~9.1 kDa, a single polypeptide chain containing 83 amino acid residues. It is an analog of IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid and a 13 amino acid length N terminus peptide extension. It has been engineered for higher biological potency in vitro, with an increased half-life. This recombinant IGF-1 LR3 product is a highly potent growth factor ideal for stem cell research and cell manufacturing applications, including cells of the ectoderm linage (oligodendrocytes, motor neurons) and mesoderm linage (osteocytes, chondrocytes, and muscle cells).

Description

Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).

Uses

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).

benefits

Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation

Side effects

Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.

IGF-1 LR3 Preparation Products And Raw materials

Raw materials

Preparation Products

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IGF-1 LR3 Suppliers

Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
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58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
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50
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
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Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ:2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6501
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58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6968
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58
Rixing Chemical CO.,LTD.
Tel
+86-852-57055271 +8613237129059
Fax
-
Email
sales@rixingbiz.com
Country
China
ProdList
232
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58
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4877
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Hebei Yime New Material Technology Co., Ltd.
Tel
+86-66697723 +86-17703311139
Email
admin@china-yime.com
Country
China
ProdList
563
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58
Hebei Yanxi Chemical Co., Ltd.
Tel
+8617531190177
Email
peter@yan-xi.com
Country
China
ProdList
5857
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58
Shijiazhuang Gantuo Biotechnology Co., Ltd
Tel
+8613373514458
Email
gantuo02@cngantuo.com
Country
China
ProdList
203
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58
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View Lastest Price from IGF-1 LR3 manufacturers

Huaian Banting Trading Co., Ltd.
Product
IGF-1LR3
Price
US $33.00-175.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
1000 boxes
Release date
2024-11-14
CONTIDE BIOTECH CO.,LTD
Product
IGF-1LR3 946870-92-4
Price
US $0.00/G
Min. Order
1G
Purity
99%
Supply Ability
20
Release date
2024-10-17
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
IGF1 LR3 946870-92-4
Price
US $10.00/box
Min. Order
1box
Purity
99%
Supply Ability
20ton
Release date
2024-05-11

946870-92-4, IGF-1 LR3Related Search:


  • IGF-1 LR3
  • CL281
  • LR3-IGF1
  • IGF-1Lr3 Igtropin
  • LR3-IGF1 (100mcg/vial
  • IGF LR3-1
  • IDF-1 LR3
  • Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1
  • LR3-IGF1, LR3-IGF-1, IGF1
  • 946870-92-4