Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate

Product Name: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate
CAS No.: 188614-01-9
Chemical Name: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate
Synonyms: Methyl-3-Oxo-3,4-Dihydro-2H-1,;Methyl 3-Oxo-2H-1,4-benzothiazine-6-carboxylate;methyl 3-oxo-4H-1,4-benzothiazine-6-carboxylate;3-oxo-4H-1,4-benzothiazine-6-carboxylic acid methyl ester;3-keto-4H-1,4-benzothiazine-6-carboxylic acid methyl ester;Methyl 3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxylate;Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate;2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate;Methyl3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate,97%;methyl 3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate
CBNumber: CB6948304
Molecular Formula: C10H9NO3S
Formula Weight: 223.25
MOL File: 188614-01-9.mol

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Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate Property

Melting point:: 180-182°
Boiling point:: 435.7±45.0 °C(Predicted)
Density: 1.343±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 12.34±0.20(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 188614-01-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B496033
Product name: Methyl3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR13646
Product name: Methyl3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxylate
Packaging: 1g
Price: $18
Updated: 2021/12/16

AK Scientific

Product number: J51369
Product name: Methyl3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate
Packaging: 1g
Price: $18
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H70-1-P9
Product name: Methyl 3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxylate
Packaging: 1g
Price: $20
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0004164
Product name: METHYL 3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZINE-6-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $124.01
Updated: 2021/12/16

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Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate Chemical Properties,Usage,Production

Synthesis

2365-48-2

412947-54-7

188614-01-9

GENERAL METHOD: A suspension of methyl 3-iodo-4-aminobenzoate (1 mmol), methyl thioglycolate (1.5 eq.), cuprous(I) iodide (0.05 mmol), trans-N,N'-dimethylcyclohexane-1,2-diamine (0.1 mmol), and cesium carbonate (2 eq.) in anhydrous 1,4-dioxane (4 mL) was added to a vial. Nitrogen was passed into the suspension to degas it for 3 min under stirring. Subsequently, the vial was sealed. The reaction mixture was heated at 100 °C (oil bath temperature) for 15 hours. After completion of the reaction, it was cooled to room temperature and filtered. The filtrates were combined and concentrated using a rotary evaporator and the resulting residue was purified by silica gel column chromatography (eluent: 5% dichloromethane solution in methanol) to afford the target product, methyl 3-carbonyl-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate, as a beige solid.

References

[1] Tetrahedron Letters, 2013, vol. 54, # 38, p. 5214 - 5216

Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate manufacturers

Career Henan Chemical Co

Product: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate 188614-01-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2000KGS
Release date: 2019-12-30

188614-01-9, Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylateRelated Search:

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Methyl 3,4-dihydro-3-oxo-2H-benzo[b][1,4]thiazine-6-carboxylate

Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate

Methyl-3-Oxo-3,4-Dihydro-2H-1,

Methyl 3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxylate

methyl 3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate

2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate

Methyl 3-Oxo-2H-1,4-benzothiazine-6-carboxylate

3-keto-4H-1,4-benzothiazine-6-carboxylic acid methyl ester

3-oxo-4H-1,4-benzothiazine-6-carboxylic acid methyl ester

methyl 3-oxo-4H-1,4-benzothiazine-6-carboxylate

JR-8617, Methyl 3,4-dihydro-3-oxo-2H-benzo[b][1,4]thiazine-6-carboxylate, 97%

2H-1,4-Benzothiazine-6-carboxylic acid, 3,4-dihydro-3-oxo-, methyl ester

Methyl3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate,97%

188614-01-9

Fused Ring Systems

Heterocycle intermediates

Esters

API intermediates