Estradiol hemihydrate

Uses

Product Name: Estradiol hemihydrate
CAS No.: 35380-71-3
Chemical Name: Estradiol hemihydrate
Synonyms: Estradiol (1250008);Estradiol Hemihydrates;EESTRADIOL HEMIHYDRATE;Estradiol Hemihydrate EP;17β-Estradiol hemihydrate;beta-Estradiol semihydrate;Estradiol Hemihydrate USP36;BETA-OESTRADIOL VETRANAL, 250 MG;Estriol EP Impurity D as Hemihydate;Ethinylestradiol EP Impurity D as Hemihydrate
CBNumber: CB6971652
Molecular Formula: C18H24O2.H2O
Formula Weight: 290.4
MOL File: 35380-71-3.mol

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Estradiol hemihydrate Property

storage temp.: 2-8°C
form: powder
BRN: 1914275
InChI: InChI=1/C18H24O2.H2O/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20;/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3;1H2/t14?,15-,16?,17-,18+;/s3
InChIKey: QJNCGXGNKJUDEM-KEFFNRLXNA-N
SMILES: C12CC[C@@H](O)[C@@]1(C)CCC1C3C=CC(O)=CC=3CC[C@@]21[H].O |&1:3,5,19,r|

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Safety

Hazard Codes: T
Risk Statements: 60-63-40-64
Safety Statements: 53-36/37-45
WGK Germany: 3
HS Code: 2937230000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H351Suspected of causing cancer

H362May cause harm to breast-fed children

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E1620000
Product name: Estradiol hemihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 100 mg
Price: $236
Updated: 2025/07/31

Sigma-Aldrich

Product number: BP729
Product name: Estradiol hemihydrate
Purity: British Pharmacopoeia (BP) Assay Standard
Packaging: 100MG
Price: $226
Updated: 2025/07/31

Sigma-Aldrich

Product number: E1620000
Product name: Estradiol hemihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e1620000
Price: $220
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: API0006694
Product name: ESTRADIOL HEMIHYDRATE
Purity: 95.00%
Packaging: 5MG
Price: $500.05
Updated: 2021/12/16

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Estradiol hemihydrate Chemical Properties,Usage,Production

Uses

Estradiol hemihydrate is a useful research chemical compound.

Uses

Estradiol hemihydrate (CAS# 35380-71-3) is a useful research chemical compound. It is used in methods of contraception using nomegestrol acetate and estradiol.

in vivo

Estradiol hemihydrate (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude^[1]. Estradiol hemihydrate (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice^[1].

Animal Model:	FBN-ARO-KO Mice^[2]
Dosage:	1 nM
Administration:	Treated for the hippocampal slices
Result:	Rescued long-term potentiation (LTP) amplitude of both male and female mice.

Animal Model:	FBN-ARO-KO Mice^[2]
Dosage:	0.0167 mg
Administration:	Alzet minipumps with Estradiol (implanted s.c.), examined 7 days after minipump implantation.
Result:	Restored hippocampal and cortical E2 levels to 93%, phosphorylation of AKT, ERK and CREB in the hippocampus and cortex to 90-95%, BDNF level to 80-90%, restored both synaptophysin and PSD95 in the forebrain. Rescued the spatial learning and memory defects.

Estradiol hemihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Estradiol hemihydrate Suppliers

China 97 Germany 1 India 9 Slovakia 1 Switzerland 1 United States 4 Global 113

J & K SCIENTIFIC LTD.

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Sigma-Aldrich

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View Lastest Price from Estradiol hemihydrate manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: Estradiol hemihydrate 35380-71-3
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-05-30

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Estradiol hemihydrate 35380-71-3
Price: US $0.00/g/Bag
Min. Order: 100g
Purity: 97.0% ~ 103.0%; EP9.5
Supply Ability: 250kg/month
Release date: 2021-06-03

Wuhan Biocar Pharmacy CO.,Ltd.

Product: Estradiol hemihydrate 35380-71-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 500kg
Release date: 2025-03-26

35380-71-3, Estradiol hemihydrateRelated Search:

BETA-OESTRADIOL VETRANAL, 250 MG

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EESTRADIOL HEMIHYDRATE

Estradiol Hemihydrates

Estradiol hemihydrateQ: What is Estradiol hemihydrate Q: What is the CAS Number of Estradiol hemihydrate Q: What is the storage condition of Estradiol hemihydrate

Estradiol (1250008)

Estradiol Valerate EP Impurity A as Hemihydrate

Ethinylestradiol EP Impurity D as Hemihydrate

Estriol EP Impurity D as Hemihydate

Estradiol Benzoate EP Impurity A as Hemihydrate

17β-Estradiol hemihydrate

17β-Oestradiol hemihydrate|||17β-Estradiol hemihydrate|||β-Estradiol hemihydrate

17β-Oestradiol hemihydrate|||β-Estradiol hemihydrate

Estradiol Hemihydrate EP

Estradiol Hemihydrate USP36

Estradiol Hemihydrate (17beta-Estradiol Hemihydrate) 1.0 mg/ml in Acetonitrile (anhydrous substance)

35380-71-3

2C18H24O2H2O