Uses
ChemicalBook > CAS DataBase List > Estradiol hemihydrate

Estradiol hemihydrate

Uses
Product Name
Estradiol hemihydrate
CAS No.
35380-71-3
Chemical Name
Estradiol hemihydrate
Synonyms
Estradiol (1250008);Estradiol Hemihydrates;EESTRADIOL HEMIHYDRATE;Estradiol Hemihydrate EP;17β-Estradiol hemihydrate;beta-Estradiol semihydrate;Estradiol Hemihydrate USP36;BETA-OESTRADIOL VETRANAL, 250 MG;Estriol EP Impurity D as Hemihydate;Ethinylestradiol EP Impurity D as Hemihydrate
CBNumber
CB6971652
Molecular Formula
C18H24O2.H2O
Formula Weight
290.4
MOL File
35380-71-3.mol
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Estradiol hemihydrate Property

storage temp. 
2-8°C
form 
powder
BRN 
1914275
InChI
InChI=1/C18H24O2.H2O/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20;/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3;1H2/t14?,15-,16?,17-,18+;/s3
InChIKey
QJNCGXGNKJUDEM-KEFFNRLXNA-N
SMILES
C12CC[C@@H](O)[C@@]1(C)CCC1C3C=CC(O)=CC=3CC[C@@]21[H].O |&1:3,5,19,r|
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Safety

Hazard Codes 
T
Risk Statements 
60-63-40-64
Safety Statements 
53-36/37-45
WGK Germany 
3
HS Code 
2937230000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H351Suspected of causing cancer

H362May cause harm to breast-fed children

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E1620000
Product name
Estradiol hemihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
100 mg
Price
$236
Updated
2025/07/31
Sigma-Aldrich
Product number
BP729
Product name
Estradiol hemihydrate
Purity
British Pharmacopoeia (BP) Assay Standard
Packaging
100MG
Price
$226
Updated
2025/07/31
Sigma-Aldrich
Product number
E1620000
Product name
Estradiol hemihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
e1620000
Price
$220
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0006694
Product name
ESTRADIOL HEMIHYDRATE
Purity
95.00%
Packaging
5MG
Price
$500.05
Updated
2021/12/16
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Estradiol hemihydrate Chemical Properties,Usage,Production

Uses

Estradiol hemihydrate is a useful research chemical compound.

Uses

Estradiol hemihydrate (CAS# 35380-71-3) is a useful research chemical compound. It is used in methods of contraception using nomegestrol acetate and estradiol.

in vivo

Estradiol hemihydrate (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude[1]. Estradiol hemihydrate (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice[1].

Animal Model:FBN-ARO-KO Mice[2]
Dosage:1 nM
Administration:Treated for the hippocampal slices
Result:Rescued long-term potentiation (LTP) amplitude of both male and female mice.
Animal Model:FBN-ARO-KO Mice[2]
Dosage:0.0167 mg
Administration:Alzet minipumps with Estradiol (implanted s.c.), examined 7 days after minipump implantation.
Result:Restored hippocampal and cortical E2 levels to 93%, phosphorylation of AKT, ERK and CREB in the hippocampus and cortex to 90-95%, BDNF level to 80-90%, restored both synaptophysin and PSD95 in the forebrain. Rescued the spatial learning and memory defects.

Estradiol hemihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Estradiol hemihydrate Suppliers

China 97 Germany 1 India 9 Slovakia 1 Switzerland 1 United States 4 Global 113
MDP ChemControl Ltd.
Tel
--
Fax
--
Email
chemcontrol@nextra.sk
Country
Slovakia
ProdList
6700
Advantage
60
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View Lastest Price from Estradiol hemihydrate manufacturers

Wuhan JiyunZen Tech Co., Ltd.
Product
Estradiol hemihydrate 35380-71-3
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-30
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Estradiol hemihydrate 35380-71-3
Price
US $0.00/g/Bag
Min. Order
100g
Purity
97.0% ~ 103.0%; EP9.5
Supply Ability
250kg/month
Release date
2021-06-03
Wuhan Biocar Pharmacy CO.,Ltd.
Product
Estradiol hemihydrate 35380-71-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
500kg
Release date
2025-03-26

35380-71-3, Estradiol hemihydrateRelated Search:

EPIMESTROL Estradiol hemihydrate Oracon 1,3,5(10)-ESTRATRIEN-2,3-DIOL-17-ONE 3-METHYL ETHER 17-ETHYLENEKETAL (16b,17a)-Estra-1,3,5(10)-triene-3,16,17-triol 1,3,5(10)-ESTRATRIEN-2,3-DIOL-17-ONE 2-METHYL ETHER 3-ACETATE 17-ETHYLENEKETAL 17-EPIESTRIOL 1,3,5(10)-ESTRATRIEN-3,17ALPHA-DIOL 3-SULFATE SODIUM 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL-6-ONE 6-CARBOXYMETHYLOXIME 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL DIACETATE Oraconal 1,3,5(10)-ESTRATRIEN-3,16-BETA, 17-ALPHA-TRIOL TRIACETATE 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL 17-ACETATE 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL 17-GLUCOSIDURONATE 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL 3-ACETATE 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL-6-ONE CYCLOTRIOL 1,3,5(10)-ESTRATRIEN-3,16-ALPHA, 17-ALPHA-TRIOL TRIACETATE

  • BETA-OESTRADIOL VETRANAL, 250 MG
  • beta-Estradiol semihydrate
  • Estra-1,3,5(10)-triene-3,17-diol(17b)-, hydrate (2:1)
  • (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol,hydrate
  • EESTRADIOL HEMIHYDRATE
  • Estradiol Hemihydrates
  • Estradiol hemihydrateQ: What is Estradiol hemihydrate Q: What is the CAS Number of Estradiol hemihydrate Q: What is the storage condition of Estradiol hemihydrate
  • Estradiol (1250008)
  • Estradiol Valerate EP Impurity A as Hemihydrate
  • Ethinylestradiol EP Impurity D as Hemihydrate
  • Estriol EP Impurity D as Hemihydate
  • Estradiol Benzoate EP Impurity A as Hemihydrate
  • 17β-Estradiol hemihydrate
  • 17β-Oestradiol hemihydrate|||17β-Estradiol hemihydrate|||β-Estradiol hemihydrate
  • 17β-Oestradiol hemihydrate|||β-Estradiol hemihydrate
  • Estradiol Hemihydrate EP
  • Estradiol Hemihydrate USP36
  • Estradiol Hemihydrate (17beta-Estradiol Hemihydrate) 1.0 mg/ml in Acetonitrile (anhydrous substance)
  • 35380-71-3
  • 2C18H24O2H2O