Synthesis
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3-Fluorobenzonitrile

Synthesis
Product Name
3-Fluorobenzonitrile
CAS No.
403-54-3
Chemical Name
3-Fluorobenzonitrile
Synonyms
M-FLUOROBENZONITRILE;M-fluoronitrile;M-FLUOROBENZONITILE;3-fluoro-benzonitril;m-Cyanofluorobenzene;3-FLUOROBENZONITRILE;3-cyanofluorobenzene;Letrozole Impurity 19;Benzonitrile, m-fluoro-;1-Fluoro-3-cyanobenzene
CBNumber
CB7100462
Molecular Formula
C7H4FN
Formula Weight
121.11
MOL File
403-54-3.mol
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3-Fluorobenzonitrile Property

Melting point:
−16 °C(lit.)
Boiling point:
182-183 °C753 mm Hg(lit.)
Density 
1.133 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.5043(lit.)
Flash point:
154 °F
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
Specific Gravity
1.133
color 
Clear colorless to yellow
BRN 
1858941
CAS DataBase Reference
403-54-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzonitrile, 3-fluoro-(403-54-3)
EPA Substance Registry System
Benzonitrile, 3-fluoro- (403-54-3)
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Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
22-37/38-41-36/37/38-20/21/22
Safety Statements 
26-39-36/37/39-36
RIDADR 
UN 3276 6.1/PG 3
WGK Germany 
3
Hazard Note 
Toxic
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
235822
Product name
3-Fluorobenzonitrile
Purity
98%
Packaging
10g
Price
$94.8
Updated
2023/01/07
TCI Chemical
Product number
F0219
Product name
3-Fluorobenzonitrile
Purity
>98.0%(GC)
Packaging
5g
Price
$45
Updated
2024/03/01
TCI Chemical
Product number
F0219
Product name
3-Fluorobenzonitrile
Purity
>98.0%(GC)
Packaging
25g
Price
$141
Updated
2024/03/01
Alfa Aesar
Product number
B23426
Product name
3-Fluorobenzonitrile, 98%
Packaging
5g
Price
$44.65
Updated
2024/03/01
Alfa Aesar
Product number
B23426
Product name
3-Fluorobenzonitrile, 98%
Packaging
25g
Price
$138.65
Updated
2024/03/01
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3-Fluorobenzonitrile Chemical Properties,Usage,Production

Synthesis

Many of the advances made in the Halex reaction have been applied to fluorodenitration reactions, for example, 3-nitrobenzonitrile reacts with KF and catalytic amounts of Ph4PBr to give 3-fluorobenzonitrile.

Chemical Properties

clear colorless to yellow liquid

Uses

3-Fluorobenzonitrile has been used in the preparation of bis(3-cyanophenoxy)phenylenes.

General Description

Microwave spectrum of 3-fluorobenzonitrile has been studied. Amination of 3-fluorobenzonitrile with morpholine in DMSO at 100°C has been investigated.

3-Fluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Fluorobenzonitrile Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
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View Lastest Price from 3-Fluorobenzonitrile manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Fluorobenzonitrile 403-54-3
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-Fluorobenzonitrile 403-54-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-Fluorobenzonitrile 403-54-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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