ChemicalBook > CAS DataBase List > ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE

ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE

Product Name: ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE
CAS No.: 327-21-9
Chemical Name: ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE
Synonyms: -1H-indole-2-carboxylate;Ethyl 6-(trifluoroMethyl)-1H-indole-2-carboxylate;6-TrifuoroMethyl-2-indolecarboxylic acid ethyl ester;6-TRIFLUOROMETHYL-2-INDOLECARBOXYLIC ACID ETHYL ESTER;6-trifluoromethyl-indole-2-carboxylic acid ethyl ester;1H-Indole-2-carboxylicacid, 6-(trifluoromethyl)-, ethyl ester
CBNumber: CB71011251
Molecular Formula: C12H10NO2F3
Formula Weight: 0
MOL File: 327-21-9.mol

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ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Property

storage temp.: Sealed in dry,Room Temperature
Appearance: Off-white to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: HCH0360253
Product name: ETHYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-2-CARBOXYLATE
Purity: 95.00%
Packaging: 5MG
Price: $505.88
Updated: 2021/12/16

Chemenu

Product number: CM124979
Product name: ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
Purity: 95%+
Packaging: 1g
Price: $273
Updated: 2021/12/16

Crysdot

Product number: CD11144661
Product name: Ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
Purity: 96%
Packaging: 1g
Price: $289
Updated: 2021/12/16

Alichem

Product number: 327219
Product name: Ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
Packaging: 1g
Price: $324.12
Updated: 2021/12/16

Chemenu

Product number: CM124979
Product name: ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
Purity: 95%+
Packaging: 5g
Price: $1066
Updated: 2021/12/16

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ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

2261-08-7

327-21-9

To a 1000 mL three-necked flask was added (E)-ethyl-2-(2-(3-(trifluoromethyl)phenyl)hydrazinyl)propionate (26 g, 94.8 mmol) synthesized in Step 1 and toluene. Subsequently, polyphosphoric acid (150 g) was slowly added to the reaction system, heated to reflux and maintained for 6 hours. After completion of the reaction, the reaction mixture was cooled to 50°C and the toluene layer was separated. The toluene layer was concentrated to dryness under reduced pressure. Toluene (50 mL) was added to the resulting solid, refluxed for 1 hour and cooled to room temperature. The recrystallized product was collected by filtration to afford ethyl 6-(trifluoromethyl)-1H-indole-2-carboxylate (1.25 g, 4.86 mmol, 5% yield).

References

[1] Patent: KR101741956, 2017, B1. Location in patent: Paragraph 0411; 0415-0417

ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE 327-21-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Career Henan Chemical Co

Product: ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE 327-21-9
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-13

327-21-9, ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATERelated Search:

6-TRIFLUOROMETHYL-1H-INDOLE-2-CARBOXYLIC ACID 6-(TRIFLUOROMETHYL)-1H-INDAZOLE 6-(Trifluoromethyl)indole ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE

6-TRIFLUOROMETHYL-2-INDOLECARBOXYLIC ACID ETHYL ESTER

Ethyl 6-(trifluoroMethyl)-1H-indole-2-carboxylate

6-TrifuoroMethyl-2-indolecarboxylic acid ethyl ester

1H-Indole-2-carboxylicacid, 6-(trifluoromethyl)-, ethyl ester

-1H-indole-2-carboxylate

6-trifluoromethyl-indole-2-carboxylic acid ethyl ester

327-21-9