ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE
- Product Name
- ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE
- CAS No.
- 327-21-9
- Chemical Name
- ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE
- Synonyms
- -1H-indole-2-carboxylate;Ethyl 6-(trifluoroMethyl)-1H-indole-2-carboxylate;6-TrifuoroMethyl-2-indolecarboxylic acid ethyl ester;6-TRIFLUOROMETHYL-2-INDOLECARBOXYLIC ACID ETHYL ESTER;6-trifluoromethyl-indole-2-carboxylic acid ethyl ester;1H-Indole-2-carboxylicacid, 6-(trifluoromethyl)-, ethyl ester
- CBNumber
- CB71011251
- Molecular Formula
- C12H10NO2F3
- Formula Weight
- 0
- MOL File
- 327-21-9.mol
ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- HCH0360253
- Product name
- ETHYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.88
- Updated
- 2021/12/16
- Product number
- CM124979
- Product name
- ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
- Purity
- 95%+
- Packaging
- 5g
- Price
- $1066
- Updated
- 2021/12/16
- Product number
- CD11144661
- Product name
- Ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
- Purity
- 96%
- Packaging
- 5g
- Price
- $1129
- Updated
- 2021/12/16
- Product number
- 327219
- Product name
- Ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
- Packaging
- 5g
- Price
- $1185.6
- Updated
- 2021/12/16
- Product number
- CM124979
- Product name
- ethyl6-(trifluoromethyl)-1H-indole-2-carboxylate
- Purity
- 95%+
- Packaging
- 1g
- Price
- $273
- Updated
- 2021/12/16
ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
2261-08-7
327-21-9
To a 1000 mL three-necked flask was added (E)-ethyl-2-(2-(3-(trifluoromethyl)phenyl)hydrazinyl)propionate (26 g, 94.8 mmol) synthesized in Step 1 and toluene. Subsequently, polyphosphoric acid (150 g) was slowly added to the reaction system, heated to reflux and maintained for 6 hours. After completion of the reaction, the reaction mixture was cooled to 50°C and the toluene layer was separated. The toluene layer was concentrated to dryness under reduced pressure. Toluene (50 mL) was added to the resulting solid, refluxed for 1 hour and cooled to room temperature. The recrystallized product was collected by filtration to afford ethyl 6-(trifluoromethyl)-1H-indole-2-carboxylate (1.25 g, 4.86 mmol, 5% yield).
References
[1] Patent: KR101741956, 2017, B1. Location in patent: Paragraph 0411; 0415-0417
ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE Suppliers
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- sales@ajchem.in
- Country
- India
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View Lastest Price from ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE manufacturers
- Product
- ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE 327-21-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10
- Product
- ETHYL 6-(TRIFLUOROMETHYL)-INDOLE-2-CARBOXYLATE 327-21-9
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13