ChemicalBook > CAS DataBase List > SUGAMMADEX

SUGAMMADEX

Product Name: SUGAMMADEX
CAS No.: 343306-71-8
Chemical Name: SUGAMMADEX
Synonyms: SugaMMadex SodiuM;Bridion;Sugammagex;Org 25969;SUGAMMADEX;Shu Glucose;shugen glucose;Unii-361lpm2T56;Sugammadex [inn];Suggmadex Sodium
CBNumber: CB71011756
Molecular Formula: C72H112O48S8
Formula Weight: 2002.15
MOL File: 343306-71-8.mol

Less

SUGAMMADEX Property

Melting point:: >208°C (dec.)
Density: 1.559±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Aqueous Acid (Slightly), Water (Slightly, Sonicated)
pka: 3.42±0.10(Predicted)
form: Solid
color: White to Pale Beige
Stability:: Hygroscopic
InChIKey: WHRODDIHRRDWEW-JLBXVEOTNA-N

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: C246000
Product name: 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-Cyclodextrin
Packaging: 50mg
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0027459
Product name: SUGAMMADEX
Purity: 95.00%
Packaging: 1G
Price: $4551.66
Updated: 2021/12/16

Ambeed

Product number: A100281
Product name: Sugammadex
Purity: 98%
Packaging: 1mg
Price: $19
Updated: 2021/12/16

Ambeed

Product number: A100281
Product name: Sugammadex
Purity: 98%
Packaging: 5mg
Price: $42
Updated: 2021/12/16

Crysdot

Product number: CD33000330
Product name: Sugammadex
Purity: 97%
Packaging: 25mg
Price: $45
Updated: 2021/12/16

Less

SUGAMMADEX Chemical Properties,Usage,Production

Description

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intubation that patients may require for surgery. Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery. Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015.

Uses

6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-Cyclodextrin, also known as Sugammadex, is used to reverse postoperative residual neuromuscular blockade.

Uses

Reversal agent for neuromuscular blocking drugs.

Definition

ChEBI: An octasaccharide derivative that is gamma-cyclodextrin in which all eight primary hydroxy groups are replaced by 2-(carboxyethyl)sulfanyl groups. Used (as the octasodium salt) for reversal of neuromuscular blockade induced by rocuronium and vecuronium in adults undergoing surgery.

Synthesis

Bromination of |?-cyclodexdrin 127 with the Vilsmeier-Haack reagent prepared by reaction of bromine with triphenylphospine in DMF gave the per-6-bromo-|?-cyclodextrin 128 in 95-98% yield. Nucleophilic displacement of the bromines of 128 with methyl 3-mercaptopropionate (129) and cesium carbon-ate at 50??C in DMF gave 6-perdeoxy-6-per(2-methoxycarbonylethyl) thio-|?-cyclodextrin 130 as a white powder. Saponification of the esters of 130 was accomplished by reaction with aqueous sodium hydroxide solution to provide sugammadex (XVII) as a glassy solid in 52% yield for the 2 steps.

in vivo

Sugammadex (100 mg/kg, IV, once) has a nephroprotective effect when given at the beginning of reperfusion after one hour of ischemic condition on rats^[2].

SUGAMMADEX Preparation Products And Raw materials

Raw materials

Preparation Products

Less

SUGAMMADEX Suppliers

China 147 China Hong Kong 1 India 22 Israel 2 Slovenia 1 Spain 2 United Kingdom 1 United States 2 Global 178

Nanjing Feihao Technology Co., Ltd.

Tel: 025-58855213
Email: hongjiling@feihongtec.com
Country: China
ProdList: 783
Advantage: 58

Changzhou Joyous Chemical Co., Ltd.

Tel: 0519-85607258 13912342323;
Fax: 0519-85607278
Email: sales@joyouschem.com
Country: China
ProdList: 294
Advantage: 60

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7782
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 027-27-81302488 15972195220
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1758
Advantage: 58

Taizhou KEDE Chemical Co., Ltd

Tel: 0576-84613060 13093829633
Fax: 0576-84613060
Email: sales@kedechemical.com
Country: China
ProdList: 299
Advantage: 60

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5001
Advantage: 55

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2991
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Anhui Shixing Chemical Co., Ltd.

Tel: 0551-65361219 17756579152
Fax: 0551-65361219
Email: hfchuandi@163.com
Country: China
ProdList: 112
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2389
Advantage: 58

Wuhan Netcom Electronic Commerce Limited

Tel: 18064670521
Fax: 0757-88210752
Email: 2355935187@ycphar.com
Country: China
ProdList: 4879
Advantage: 58

CHENGHUI PHARMACEUTICAL GROUP LTD

Tel: 531-58897070 15254140813
Fax: 0531-58897046
Email: market@jnchsd.com
Country: China
ProdList: 235
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Shanghai Tube Pharmaceutical Co., Ltd.

Tel: 021-54338626 18017892860
Fax: 021-54338626
Email: sales@tubepharm.com
Country: China
ProdList: 2572
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-88380327 17691182729
Fax: 029-88380327
Email: 1018@dideu.com
Country: China
ProdList: 2011
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1991
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Aishilun biotechnology (Shanghai) co., LTD

Tel: 021-50676523 18019098996
Email: info@acelybio.com
Country: China
ProdList: 3960
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7924
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Xi'an MC Biotech, Co., Ltd.

Tel: 029-89275612 +8618991951683
Fax: 8618991951683
Email: mcbio_sales@163.com
Country: China
ProdList: 2251
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10237
Advantage: 58

Wuhan Fortuna Chemical Co., Ltd

Tel: +86-027-59207850 +86-13986145403;
Fax: 86-27-59524646
Email: info@fortunachem.com
Country: China
ProdList: 5990
Advantage: 58

Baoji Guokang Healthchem Co., Ltd.

Tel: +86-0917-3909592 +86-13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9209
Advantage: 58

Baoji Guokang Healthchem co.,ltd

Tel: +8615604608665 15604608665
Email: dominicguo@gk-bio.com
Country: CHINA
ProdList: 9414
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15109
Advantage: 58

Hebei Minshang Biological Technology Co. LTD

Tel: +8618132649059 18132649059
Fax: +8618132649059
Email: monica@hbminshang.cn
Country: CHINA
ProdList: 200
Advantage: 58

Shanxi Xuanran Import and Export Trade Co., Ltd.

Tel: +8617735180244
Email: mike_yan@xuanranglobal.com
Country: CHINA
ProdList: 4017
Advantage: 58

HONG KONG IPURE BIOLOGY CO.,LIMITED

Tel: 86 18062405514 18062405514
Email: ada@ipurechemical.com
Country: CHINA
ProdList: 3461
Advantage: 58

Hebei Miaobian Biotechnology Co., Ltd

Tel: +8617733850068
Country: CHINA
ProdList: 967
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9990
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Zhongxiang Yaowei Biological Technology Co., Ltd.

Tel: 15337241005 13260682861
Email: w13260682861@qq.com
Country: China
ProdList: 2434
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

ShenZhen Davoos Tech Ltd

Tel: 0752-5555973 13923768523
Email: 95372103@qq.com
Country: China
ProdList: 670
Advantage: 58

Shenzhen Excellent Biotech Co., Ltd.

Tel: 13480692018
Email: ramyan@ex-biotech.com
Country: CHINA
ProdList: 954
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Nanjing Becas pharmatech Ltd.

Tel: 13912903754
Email: info@becaspharma.com
Country: China
ProdList: 2763
Advantage: 58

Wuhan kemike Biomedical Technology Co., Ltd

Tel: 027-13163388153 13163388153
Email: yeqiu416@163.com
Country: China
ProdList: 9810
Advantage: 58

Qingdao haohai anjie pharmaceutical technology co., ltd.

Tel: 156-6622-8711 18639325623
Email: chen.wanglin@hmgj.group
Country: China
ProdList: 1905
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-029-81024372 17792795018
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 9996
Advantage: 58

Less

View Lastest Price from SUGAMMADEX manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: Sugammadex Sodium
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-22

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Sugammadex 343306-71-8
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 99%min HPLC
Supply Ability: 100kgs
Release date: 2021-08-26

Wuhan Biocar Pharmacy CO.,Ltd.

Product: Sugammadex 343306-71-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 800kg
Release date: 2025-03-05

343306-71-8, SUGAMMADEXRelated Search:

Sodium gluconate Nisin PIERICIDIN A CHONDROITIN SULFATE (BOVINE) Rivaroxaban Artemether Rocuronium bromide Donepezil Sugammadex sodium OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN SUGAMMADEX

Shu Glucose

SUGAMMADEX

Org 25969

Sugammadex [inn]

Unii-361lpm2T56

SugaMMadex SodiuM

Sugammagex

Bridion

γ-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-

Sodium sulcoglucan

Suggmadex Sodium

6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-Cyclodextrin

Sugammadex Impurity 58

High purity CAS 343306-71-8 SUGAMMADEX in stock

g-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G, 6H-octathio-

shugen glucose

343306-71-8

C72H112O48S8