Azaphen hydrochloride
- Product Name
- Azaphen hydrochloride
- CAS No.
- 24853-80-3
- Chemical Name
- Azaphen hydrochloride
- Synonyms
- Azafen;azaphen;Pipofezine HCl;AZAPHENONXAZINE;Azaphen (Pipofezine);Azaphenonxazine 2HCl;Azaphen hydrochloride;Azaphen, 10 mM in DMSO;Pipofezin hydrochloride;Pipofezine hydrochloride
- CBNumber
- CB71011938
- Molecular Formula
- C16H19N5O.2ClH
- Formula Weight
- 370.28
- MOL File
- 24853-80-3.mol
Azaphen hydrochloride Property
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Solid
Safety
- Toxicity
- LD50 orl-rat: 1 g/kg ZPPLBF 114,787,75
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FA146882
- Product name
- AzaphenHydrochloride
- Packaging
- 1mg
- Price
- $51
- Updated
- 2021/12/16
- Product number
- FA146882
- Product name
- AzaphenHydrochloride
- Packaging
- 2mg
- Price
- $89
- Updated
- 2021/12/16
- Product number
- CS-0632
- Product name
- Azaphen
- Packaging
- 100mg
- Price
- $166
- Updated
- 2021/12/16
- Product number
- FA146882
- Product name
- AzaphenHydrochloride
- Packaging
- 5mg
- Price
- $177
- Updated
- 2021/12/16
- Product number
- FA146882
- Product name
- AzaphenHydrochloride
- Packaging
- 10mg
- Price
- $307
- Updated
- 2021/12/16
Azaphen hydrochloride Chemical Properties,Usage,Production
Uses
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIs Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment of depression.
Safety Profile
Poison by ingestion, intravenous,and subcutaneous routes. When heated to decompositionit emits very toxic fumes of HCl and NOx. Anantidepressant.
References
[1] Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(5), 237-241.
[2] Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. PMID:16281382
[3] Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. PMID:557800
[4] Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. PMID:1112390
[5] Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6. PMID:4450998
Azaphen hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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