ChemicalBook > CAS DataBase List > o-methylisourea

o-methylisourea

Product Name
o-methylisourea
CAS No.
2440-60-0
Chemical Name
o-methylisourea
Synonyms
Methyl carbamimidate;o-methylisourea (abbreviate OMIU);o-methylisourea;o-Methylisouronium;Methoxyformamidine;ORTHO-METHYLISOUREA;24285-39-0 (Sulfate);29427-58-5 (Monosulfate);Fluorouracil Impurity 16;5329-33-9 (Hydrochloride)
CBNumber
CB71013558
Molecular Formula
C2H6N2O
Formula Weight
74.08
MOL File
2440-60-0.mol
More
Less

o-methylisourea Property

Melting point:
44-45 °C
Boiling point:
66.9±23.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
solubility 
free base readily sol most organic solvents. Salts sol water, methanol, ethanol.
pka
pK1:9.72(＋1) (25°C)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
B497138
Product name
MethylCarbamimidate
Packaging
100mg
Price
$90
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0078925
Product name
METHOXYMETHANIMIDAMIDE
Purity
95.00%
Packaging
1G
Price
$679.14
Updated
2021/12/16
More
Less

o-methylisourea Chemical Properties,Usage,Production

Uses

O-methylisourea can be used in the synthesis of heterocyclic compounds; it is a guanylation reagent and a selective alkylating agent.

Application

Methyl Carbamimidate is preparation of Ph (3-methoxy-1,2,4-thiadiazol-5-yl)carbamate from O-methylisourea hydrochloride.

Preparation

O-methylisourea hydrochloride is prepared in 69-80% yield by adding 1.15 equiv  HCl(g) with ice cooling to cyanamide dissolved in excess anhydrous methanol. The free base is obtained  from the salt using powdered KOH in a water-ether mixture or with sodium methoxide in methanol. The  monoacetate salt can be prepared from the free base with 1 equiv of HOAc. Drying: vacuum desiccator  over P2O5.

storage

Salts are hygroscopic and should be stored in a desiccator even for  brief periods. Heating O-methylisourea to decomposition can liberate toxic fumes of NOx. Use in a fume  hood.

o-methylisourea Preparation Products And Raw materials

Raw materials

O-methylisourea

Preparation Products

More
Less

o-methylisourea Suppliers

China 16 Finland 1 United Kingdom 1 United States 3 Global 21
AmplaChem, Inc.
Tel
--
Fax
--
Email
info@amplacheminc.com
Country
United States
ProdList
428
Advantage
50
ARVI Fine Organic Chemicals Co., Ltd.
Tel
--
Fax
--
Email
vbaden2@yahoo.com
Country
United States
ProdList
249
Advantage
50
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30

2440-60-0, o-methylisoureaRelated Search:

O-Methylisourea hemisulfate 2,2'-Cyclouridine O-Methylisourea hydrochloride O-(4-NITROBENZYL)-N,N'-DIISOPROPYLISOUREA 2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride O-METHYLISOUREA SULFATE Ancitabine PEMOLINE o-methylisourea 2-O-METHYLTHYMIDINE 2-AMINO-2-OXAZOLINE HYDROCHLORIDE O-METHYL-N,N'-DIISOPROPYLISOUREA 3-(4-BROMOPHENYL)-5-(4-METHOXYPHENOXY)[1,2,4]TRIAZOLO[4,3-C]QUINAZOLINE 3-(2-FLUOROPHENYL)-5-PHENOXY[1,2,4]TRIAZOLO[4,3-C]QUINAZOLINE 2,4-DICHLOROPHENYL 3-(2-FLUOROPHENYL)[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL ETHER 5-Phenyl-2-(2-propynylamino)-2-oxazolin-4-one 2-[(4-CHLOROPHENYL)AMINO]-4H-3,1-BENZOXAZIN-4-ONE 3-(2-FLUOROPHENYL)-5-(4-METHOXYPHENOXY)[1,2,4]TRIAZOLO[4,3-C]QUINAZOLINE

  • 24285-39-0 (Sulfate)
  • 29427-58-5 (Monosulfate)
  • 52328-05-9 (Sulfate[2:1])
  • 5329-33-9 (Hydrochloride)
  • o-Methylisouronium
  • o-methylisourea
  • ORTHO-METHYLISOUREA
  • Carbamimidic acid methyl ester
  • Methoxyformamidine
  • o-methylisourea (abbreviate OMIU)
  • Carbamimidic acid,methyl ester (9CI)
  • Methyl carbamimidate
  • Fluorouracil Impurity 16
  • 2440-60-0
  • H2NCOCH3NH