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BAMIFYLLINE

Product Name
BAMIFYLLINE
CAS No.
2016-63-9
Chemical Name
BAMIFYLLINE
Synonyms
8102CB;8102 CB;CB-8102;Bax-2739Z;Bamifyllin;BAMIFYLLINE;Bamiphylline;8-BENZYL-7-(2-(HYDROXYETHYL)AMINO)ETHYL)THEOPHYLLINE;8-benzyl-7-(2-(N-ethyl-2-hydroxyethylamino)ethyl)theophylline;8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
CBNumber
CB7103685
Molecular Formula
C20H27N5O3
Formula Weight
385.46
MOL File
2016-63-9.mol
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BAMIFYLLINE Property

Melting point:
80-80.5°
Boiling point:
619.0±65.0 °C(Predicted)
Density 
1.25
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
pka
14.73±0.10(Predicted)
form 
Solid
color 
White to Pale Brown
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B119910
Product name
Bamifylline
Packaging
1mg
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010768
Product name
BAMIFYLLINE
Purity
95.00%
Packaging
5MG
Price
$504.65
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010768
Product name
BAMIFYLLINE
Purity
95.00%
Packaging
5G
Price
$3817.8
Updated
2021/12/16
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BAMIFYLLINE Chemical Properties,Usage,Production

Originator

Bamifylline,ZYF Pharm Chemical

Uses

Bronchodilator.

Uses

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.

Definition

ChEBI: Bamifylline is an oxopurine.

Manufacturing Process

A mixture of 100 kg of 8-benzyltheophilline, 36 L of N-ethylethanolamine, 300 L of 1,2-dichlorethane and 71 kg of sodium carbonate was refluxed for 24 hours. Then 36 L of N-ethylethanolamine was added and the reaction mixture was refluxed. After cooling to the mixture was added the water and hydrochloric acid. The organic phase was extracted with hydrochloric acid. The acidic phase was neutralized with sodium carbonate and the 7-(N-ethyl-N-β- hydroxyethylaminoethyl)-8-benzyltheophilline was extracted with dichloromethane. The solvent was evaporated and the free base of 7-(N-ethyl- N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was dissolved in methanol. Hydrochloride of 7-(N-ethyl-N-β-hydroxyethylaminoethyl)-8-benzyltheophilline was obtained by addition to the solution the hydrochloric acid; yield 81%, melting point 185-186°C.

Therapeutic Function

Bronchodilator, Coronary vasodilator

BAMIFYLLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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BAMIFYLLINE Suppliers

China 27 Europe 2 France 1 Germany 1 India 1 South Korea 1 United Kingdom 4 United States 8 Global 45
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Tractus USA LLC
Tel
--
Fax
--
Country
United States
ProdList
227
Advantage
60
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55

2016-63-9, BAMIFYLLINERelated Search:

Theophylline etamiphyllin BAMIFYLLINE 8-BENZYLTHEOPHYLLINE dimethazan AC 119 1-Methylcaffeine bamifylline hydrochloride ,BAMIFYLLINE HCL 7-(2-aminoethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

  • BAMIFYLLINE
  • 8-BENZYL-7-(2-(HYDROXYETHYL)AMINO)ETHYL)THEOPHYLLINE
  • 8102 CB
  • 8102CB
  • Bamiphylline
  • Bax-2739Z
  • CB-8102
  • 8-benzyl-7-(2-(N-ethyl-2-hydroxyethylamino)ethyl)theophylline
  • 8-benzyl-7-{2-[ethyl(2-hydroxyethyl)aMino]ethyl}-1,3-diMethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
  • 1H-Purine-2,6-dione,7-[2-[ethyl(2-hydroxyethyl)aMino]ethyl]-3,7-dihydro-1,3-diMethyl-8-(phenylMethyl)-
  • 7-[2-[Ethyl(2-hydroxyethyl)amino]ethyl]-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-1H-purine-2,6-dione
  • Bamifyllin
  • Bamifylline HclQ: What is Bamifylline Hcl Q: What is the CAS Number of Bamifylline Hcl Q: What is the storage condition of Bamifylline Hcl
  • 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
  • 2016-63-9
  • C20H27N5O3