Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- Product Name
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- CAS No.
- 478148-62-8
- Chemical Name
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- Synonyms
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- CBNumber
- CB71048198
- Molecular Formula
- C8H5NO3
- Formula Weight
- 163.13
- MOL File
- 478148-62-8.mol
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Property
- Boiling point:
- 366.8±22.0 °C(Predicted)
- Density
- 1.455
- storage temp.
- 2-8°C
- pka
- 1.06±0.30(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F865315
- Product name
- Furo[2,3-C]pyridine-5-carboxylicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 119205
- Product name
- Furo[2,3-c]pyridine-5-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $429
- Updated
- 2021/12/16
- Product number
- CHM0392684
- Product name
- FURO[2,3-C]PYRIDINE-5-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.62
- Updated
- 2021/12/16
- Product number
- 119205
- Product name
- Furo[2,3-c]pyridine-5-carboxylic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1072
- Updated
- 2021/12/16
- Product number
- W6445
- Product name
- Furo[2,3-c]pyridine-5-carboxylicacid
- Packaging
- 5g
- Price
- $2786
- Updated
- 2021/12/16
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Chemical Properties,Usage,Production
Synthesis
478148-61-7
478148-62-8
The general procedure for the synthesis of furo[2,3-c]pyridine-5-carboxylic acid from furo[2,3-c]pyridine-5-carboxaldehyde was as follows: furo[2,3-c]pyridine-5-carboxaldehyde (850 mg, 5.8 mmol) was dissolved in 10 mL of dimethyl sulfoxide (DMSO). To this solution was added a 3 mL aqueous solution of potassium dihydrogen phosphate (KH2PO4, 221 mg, 1.6 mmol) followed by a 7 mL aqueous solution of sodium chlorite (NaClO2, 920 mg, 8.2 mmol). The reaction mixture was stirred for 3 h at room temperature. After completion of the reaction, the reaction mixture was diluted with 25 mL of water, the pH was adjusted to 10 with 2 N sodium hydroxide (NaOH) solution, and then extracted with ether (3 x 20 mL). The combined ether layers were discarded. The aqueous layer was adjusted to pH 3.5 with 10% aqueous hydrochloric acid (HCl) solution and then extracted with 10% methanol/dichloromethane (MeOH/CH2Cl2, 13 × 10 mL). The combined organic layers were dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated in vacuum to give a light-colored oil. Residual DMSO was removed at room temperature under a stream of nitrogen (N2) to give a white paste. The paste was dissolved in methanol (MeOH) and concentrated to dryness. The white solid was washed with ether and dried to give the crude furano[2,3-c]pyridine-5-carboxylic acid (94% yield). The compound with molecular formula C8H5NO3 was obtained by mass spectrometry (ESI) analysis with a mass-to-charge ratio (m/z) of 162.8 (M-H)-.
References
[1] Patent: US2003/153595, 2003, A1
[2] Patent: US2003/45540, 2003, A1
[3] Patent: WO2004/52894, 2004, A1. Location in patent: Page 36
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 14, p. 4425 - 4436
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Suppliers
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 13477084141; 13477084141
- Fax
- +86(27)65566697
- sales@luohuapharm.com
- Country
- China
- ProdList
- 468
- Advantage
- 60
- Tel
- 0532-0532-88191853 13061484198
- Fax
- +86-532-88191853
- sales@carelongchem.com
- Country
- China
- ProdList
- 439
- Advantage
- 57
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- +86 0510-85629785
- Fax
- +86 0510-85625359
- Country
- China
- ProdList
- 2327
- Advantage
- 58
- Tel
- 13971561712, 13995564702, 027-50664929
- Fax
- 027-50664927
- hbeixys2001@163.com
- Country
- China
- ProdList
- 3120
- Advantage
- 55
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9923
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- +86-023-62871537
- sales@rosewachem.com
- Country
- China
- ProdList
- 2803
- Advantage
- 58
- Tel
- 021-20432219 13918097649
- Fax
- QQ79021576
- li_jinfei@acblock-lab.com
- Country
- China
- ProdList
- 9673
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- qq:1454668768
- 1454668768@qq.com
- Country
- China
- ProdList
- 14873
- Advantage
- 58
- Tel
- 13969155946
- 1461866103@qq.com
- Country
- China
- ProdList
- 16111
- Advantage
- 58
- Tel
- 0371-55289822 18737195735
- Fax
- QQ:483339295
- 483339295@qq.com
- Country
- China
- ProdList
- 7587
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- nanfengdrug@163.com; 18616377689
- nanfengdrug@163.com
- Country
- China
- ProdList
- 20009
- Advantage
- 58
- Tel
- 650-6922368
- sales@achemblock.com
- Country
- China
- ProdList
- 2992
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- +86-02787215551 +86-19945035818
- Fax
- 027-87215551
- 2936752263@qq.com
- Country
- China
- ProdList
- 7985
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 0371-0371-55153829 18003835034
- 2853979819@qq.com
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 0573-85609002 18367600069;
- zhejia01@163.com
- Country
- China
- ProdList
- 8887
- Advantage
- 58
- Tel
- 15387063101
- 2881924050@qq.com
- Country
- China
- ProdList
- 9958
- Advantage
- 58
- Tel
- 1173954148q
- meishipharma@126.com
- Country
- China
- ProdList
- 20033
- Advantage
- 58
- Tel
- 13564723712
- 22265687@qq.com
- Country
- China
- ProdList
- 342
- Advantage
- 58
- Tel
- 4000255188 13327728092
- sales@pharmablock.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 18600731423
- jason_gao@yl-pharminblock.com
- Country
- China
- ProdList
- 1952
- Advantage
- 58
- Tel
- 17316404525 17316404525
- 209533805@qq.com
- Country
- China
- ProdList
- 9765
- Advantage
- 58
- Tel
- +undefined18143011203
- info@chemextension.com
- Country
- China
- ProdList
- 42056
- Advantage
- 58
- Tel
- +undefined18600731423
- jason_gao@yl-pharminblock.com
- Country
- China
- ProdList
- 1944
- Advantage
- 58
- Tel
- +undefined18958062155
- sales@zjgoldpharm.com
- Country
- China
- ProdList
- 5899
- Advantage
- 58
- Tel
- 17681885887
- Country
- CHINA
- ProdList
- 138
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6650
- Advantage
- 58
- Tel
- --
- Fax
- --
- jicp.good@163.com
- Country
- China
- ProdList
- 247
- Advantage
- 0
View Lastest Price from Furo[2,3-c]pyridine-5-carboxylic acid (9CI) manufacturers
- Product
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI) 478148-62-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-02-20