((S)-piperidin-3-yl)methanol

Product Name: ((S)-piperidin-3-yl)methanol
CAS No.: 144539-77-5
Chemical Name: ((S)-piperidin-3-yl)methanol
Synonyms: 3(S)-Piperidinemethanol;(3S)-3-PiperidineMethanol;(S)-Piperidine-3-methanol;3-Piperidinemethanol, (3S)-;(3S)-piperidin-3-ylMethanol;((S)-piperidin-3-yl)methanol;(S)-3-Hydroxymethyl-piperidine, 99.8%ee, 98%
CBNumber: CB71094069
Molecular Formula: C6H13NO
Formula Weight: 115.17
MOL File: 144539-77-5.mol

More

Less

((S)-piperidin-3-yl)methanol Property

Boiling point:: 240.4±0.0 °C(Predicted)
Density: 0.951
refractive index: 1.451
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 14.93±0.10(Predicted)
Appearance: Colorless to light yellow Solid-liquid mixture

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P481970
Product name: (S)-3-Piperidinemethanol
Packaging: 2.5g
Price: $1055
Updated: 2021/12/16

Matrix Scientific

Product number: 073570
Product name: (S)-(Piperidin-3-yl)methanol
Purity: 95+%
Packaging: 1g
Price: $94
Updated: 2021/12/16

Activate Scientific

Product number: AS33796-3S
Product name: (S)-3-(Hydroxymethyl)piperidine
Purity: 95+% ee
Packaging: 1g
Price: $125
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-43
Product name: (3S)-Piperidin-3-ylmethanol
Packaging: 250mg
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: W3153
Product name: (S)-(Piperidin-3-yl)methanol
Packaging: 1g
Price: $300
Updated: 2021/12/16

More

Less

((S)-piperidin-3-yl)methanol Chemical Properties,Usage,Production

Uses

(S)-3-Piperidinemethanol is used to study enzymic chemoselective and enantioselective acyl transfers in hydroxymethylpiperidines.

Uses

((S)-piperidin-3-yl)methanol is used to study enzymic chemoselective and enantioselective acyl transfers in hydroxymethylpiperidines.

Synthesis

37675-18-6

4606-65-9

General procedure for the synthesis of 3-hydroxymethylpiperidine from ethyl (S)-3-piperidinecarboxylate: lithium aluminum hydride (LAH, 118 mL, 1.0 M in ether, 1.0 equiv.) was slowly added to a solution of tetrahydrofuran (THF, 250 mL) of the product of step A (18.5 g, 0.125 mmol) over a period of 20 min at 0 °C. The reaction mixture was gradually warmed to room temperature and subsequently heated to reflux for 2 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was quenched by slow addition of saturated sodium sulfate (Na2SO4) solution. The resulting slurry was dried by the addition of anhydrous sodium sulfate (Na2SO4), filtered through diatomaceous earth and concentrated to give a colorless oily product (13.7 g, 98% crude yield). The product was detected by chemical ionization mass spectrometry (CIMS) showing a molecular ion peak (MH+) of 116; the specific optical rotation ([α]20D) was -8.4° (determined by dissolving 5.0 mg of the sample in 2 mL of methanol).

References

[1] Patent: US2003/229099, 2003, A1. Location in patent: Page 174
[2] Patent: US2004/122018, 2004, A1. Location in patent: Page 208
[3] Patent: EP1140904, 2005, B1. Location in patent: Page/Page column 33
[4] Patent: EP1553074, 2005, A1. Location in patent: Page/Page column 37
[5] Patent: WO2014/173855, 2014, A1. Location in patent: Page/Page column 17

((S)-piperidin-3-yl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

((S)-piperidin-3-yl)methanol Suppliers

Canada 1 China 65 India 3 Switzerland 2 United States 9 Global 80

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Rintech, Inc.

Tel: --
Fax: --
Email: info@rintechinc.com
Country: United States
ProdList: 3416
Advantage: 60

More

Less

View Lastest Price from ((S)-piperidin-3-yl)methanol manufacturers

Honest Joy Holdings Limited

Product: (S)-(Piperidin-3-yl)methanol 144539-77-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.1%
Supply Ability: 100 tons
Release date: 2022-01-26

Career Henan Chemical Co

Product: ((S)-piperidin-3-yl)methanol 144539-77-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

144539-77-5, ((S)-piperidin-3-yl)methanolRelated Search:

BENZOYLECGONINE Cevadine GELSEMINE COCAINE Aconitine METHYLLYCACONITINE CITRATE SERPENTINE HYDROGEN TARTRATE COCAINE HYDROCHLORIDE LAPPACONITINE HYDROBROMIDE CONDELPHINE ECGONINE METHYL ESTER HYDROCHLORIDE ECGONIN HCL COCAINE PROPYL ESTER HCL 4-hydroxynipecotic acid NORCOCAINE HYDROCHLORIDE BENZOYLECGONINE-D3 BENZOYL NORECGONINE 3-BENZOYLOXY-8-[METHYL-D3]-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID TETRAHYDRATE

((S)-piperidin-3-yl)methanol

(3S)-piperidin-3-ylMethanol

(3S)-3-PiperidineMethanol

3(S)-Piperidinemethanol

(S)-3-Hydroxymethyl-piperidine, 99.8%ee, 98%

(S)-Piperidine-3-methanol

3-Piperidinemethanol, (3S)-

144539-77-5

Chiral Reagents

Heterocycles

Intermediates