METHYLLYCACONITINE CITRATE

Product Name
METHYLLYCACONITINE CITRATE
CAS No.
112825-05-5
Chemical Name
METHYLLYCACONITINE CITRATE
Synonyms
MLA;METHYLLYCACONITINE CITRATE;Methyllycaconitine citrate salt;MLA (Methyllycaconitine Citrate);Cytotoxic T-Lymphocyte-Associated Antigen 8;INTERLEUKIN-17A; IL-17; IL-17A; CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 8; CTLA-8; IL17A; CTLA8; IL17;[1A,4(S),6B,14A,16B]-20-ETHYL-1,6,14,16-TETRAMETHOXY-4-[[[2-(3-METHYL-2,5-DIOXO-1-PYRROLIDINYL)BENZOYL]OXY]METHYL]ACONITANE-7,8-DIOL CITRATE;[1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate salt;[1ALPHA,4(S),6BETA,14ALPHA,16BETA]-20-ETHYL-1,6,14,16-TETRAMETHOXY-4[[[2-(3-METHYL-2,5-DIOXO-1-PYRROLIDINYL)BENZOYL]OXY]METHYL]-ACONITANE-7,8-DIOL CITRATE
CBNumber
CB8113766
Molecular Formula
C43H58N2O17
Formula Weight
874.92
MOL File
112825-05-5.mol
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METHYLLYCACONITINE CITRATE Property

storage temp. 
−20°C
solubility 
H2O: 42 mg/mL
form 
solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M168
Product name
Methyllycaconitine citrate salt
Purity
from Delphinium brownii seeds, ≥96% (HPLC)
Packaging
5mg
Price
$95.3
Updated
2021/12/16
Sigma-Aldrich
Product number
M168
Product name
Methyllycaconitine citrate salt
Purity
from Delphinium brownii seeds, ≥96% (HPLC)
Packaging
25mg
Price
$339
Updated
2021/12/16
Tocris
Product number
1029
Product name
Methyllycaconitinecitrate
Packaging
25
Price
$413
Updated
2021/12/16
Tocris
Product number
1029
Product name
Methyllycaconitinecitrate
Packaging
5
Price
$95
Updated
2021/12/16
TRC
Product number
M315808
Product name
MethyllycaconitineCitrate
Packaging
100mg
Price
$790
Updated
2021/12/16
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METHYLLYCACONITINE CITRATE Chemical Properties,Usage,Production

Uses

Methyllycaconitine citrate salt has been used as an α7 nicotinic acetylcholine receptor (α7 nAChR) antagonist:
  • to study its effects on inflammatory response in rats post nicotine treatment
  • to block the activity of galantamine
  • to study its effects on the hepatic branch of the vagus nerve (hVNS) in rats

Biochem/physiol Actions

Methyllycaconitine (MLA) is an α7 nicotinic acetylcholine receptor (α7 nAChR) antagonist. It is a norditerpenoid alkaloid synthesized by several species of Delphinium. MLA binds to the binding site of neuronal α-bungarotoxin. Low doses of MLA are associated with improvement of cognition in animals.

METHYLLYCACONITINE CITRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYLLYCACONITINE CITRATE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
BOC Sciences
Email
info@bocsci.com
Country
United States
ProdList
21113
Advantage
65
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
4041
Advantage
66
Sigma-Aldrich
Tel
021-61415566- ;
Email
orderCN@merckgroup.com;orderCN@merckgroup.com
Country
China
ProdList
50837
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9918
Advantage
58
Chengdu Biopurify Phytochemicals Ltd.
Tel
18080483897
Email
maggie@biopurify.com
Country
China
ProdList
2712
Advantage
58
Aktin Chemicals, Inc.
Tel
028-85159085
Fax
86-28-85159085 Ex:604
Email
info@aktinchem.com
Country
CHINA
ProdList
1026
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000-
Email
thinklifescience@126.com
Country
China
ProdList
19801
Advantage
58
Absin Bioscience Inc.
Tel
Email
info@absin.cn
Country
China
ProdList
23933
Advantage
58
Aktin Chemicals, Inc.
Tel
028-85159085-
Email
info@aktinchem.com
Country
China
ProdList
1273
Advantage
58

112825-05-5, METHYLLYCACONITINE CITRATERelated Search:


  • METHYLLYCACONITINE CITRATE
  • [1ALPHA,4(S),6BETA,14ALPHA,16BETA]-20-ETHYL-1,6,14,16-TETRAMETHOXY-4[[[2-(3-METHYL-2,5-DIOXO-1-PYRROLIDINYL)BENZOYL]OXY]METHYL]-ACONITANE-7,8-DIOL CITRATE
  • [1A,4(S),6B,14A,16B]-20-ETHYL-1,6,14,16-TETRAMETHOXY-4-[[[2-(3-METHYL-2,5-DIOXO-1-PYRROLIDINYL)BENZOYL]OXY]METHYL]ACONITANE-7,8-DIOL CITRATE
  • MLA
  • [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate salt
  • Methyllycaconitine citrate salt
  • Cytotoxic T-Lymphocyte-Associated Antigen 8
  • INTERLEUKIN-17A; IL-17; IL-17A; CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 8; CTLA-8; IL17A; CTLA8; IL17
  • MLA (Methyllycaconitine Citrate)
  • 112825-05-5