NOCARDAMINE

Product Name: NOCARDAMINE
CAS No.: 26605-16-3
Chemical Name: NOCARDAMINE
Synonyms: Nocardamin;NOCARDAMINE;deferrioxamine E;PROFERRIOXAMIN E;Desferrioxamine E;Desferri-ferrioxamine E;Nocardamine (Deferrioxamine E);1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone;6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone;1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-
CBNumber: CB7117055
Molecular Formula: C27H48N6O9
Formula Weight: 600.7
MOL File: 26605-16-3.mol

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NOCARDAMINE Property

Melting point:: 192-195°
Density: 1.162±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (5 mg/ml)
form: solid
pka: 8?+-.0.20(Predicted)
color: Off-white
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28745
Product name: Nocardamine
Packaging: 1mg
Price: $109
Updated: 2024/03/01

TRC

Product number: N634083
Product name: Nocardamine
Packaging: 1mg
Price: $205
Updated: 2021/12/16

AK Scientific

Product number: 1037CB
Product name: Nocardamine
Packaging: 1mg
Price: $255
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CN2-0150-M005
Product name: Nocardamine
Purity: ≥95%(HPLC)
Packaging: 5mg
Price: $480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019192
Product name: NOCARDAMINE
Purity: 95.00%
Packaging: 5MG
Price: $515.55
Updated: 2021/12/16

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NOCARDAMINE Chemical Properties,Usage,Production

Description

Nocardamine is a ferrioxamine siderophore that has been found in Streptomyces and has diverse biological activities. It chelates iron in a chrome azurol S assay (IC₅₀ = 9.9 μM). Nocardamine inhibits M. smegmatis and M. bovis biofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron. It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC₅₀s = 6, 18, 12, and 14 μM, respectively). Nocardamine also induces morphological changes in BM-N4 insect cells.

Uses

Nocardamine is a cyclic siderophore.

Definition

ChEBI: A cyclic hydroxamic acid siderophore that is produced by several bacterial species and exhibits antitumour activity.

storage

+4°C

References

Normant et al. (2020), Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa: Exclusive Involvement of the FoxA Outer Membrane Transporter; ACS Chem. Biol. 15 2741 Ueki et al. (2009), Nocardamin Production by Streptomyces avermitilis; Actinomycetologica 23 34 Yan et al. (2021), Ferroptosis: mechanisms and links with diseases; Signal Transduct. Target Ther. 6 49 Kalinovskaya et al. (2011), Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activity; Res. 166 654 Mahmud et al. (2022), Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809; Molecules 27 2292

NOCARDAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NOCARDAMINE Suppliers

China 24 Germany 1 India 2 United States 6 Global 33

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-89903882 13626641628
Email: jiangnan@huidabiotech.com
Country: China
ProdList: 3656
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Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
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Zhejiang Huida Biotech Co., LTD

Tel: 0571-0571-89903882 15990081639
Email: sunshixuan@huidabiotech.com
Country: China
ProdList: 3705
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
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Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 39988
Advantage: 58

26605-16-3, NOCARDAMINERelated Search:

DO264 N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) AZ20 BI 2536 DEFEROXAMINE MESYLATE NOCARDAMINE

NOCARDAMINE

PROFERRIOXAMIN E

deferrioxamine E

1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone

6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone

Desferri-ferrioxamine E

Desferrioxamine E

Nocardamin

Nocardamine (Deferrioxamine E)

1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-

26605-16-3

C27H48N6O9