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NOCARDAMINE

Product Name
NOCARDAMINE
CAS No.
26605-16-3
Chemical Name
NOCARDAMINE
Synonyms
Nocardamin;NOCARDAMINE;deferrioxamine E;PROFERRIOXAMIN E;Desferrioxamine E;Desferri-ferrioxamine E;Nocardamine (Deferrioxamine E);1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone;6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone;1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-
CBNumber
CB7117055
Molecular Formula
C27H48N6O9
Formula Weight
600.7
MOL File
26605-16-3.mol
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NOCARDAMINE Property

Melting point:
192-195°
Density 
1.162±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO (5 mg/ml)
form 
solid
pka
8?+-.0.20(Predicted)
color 
Off-white
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28745
Product name
Nocardamine
Packaging
1mg
Price
$109
Updated
2024/03/01
TRC
Product number
N634083
Product name
Nocardamine
Packaging
1mg
Price
$205
Updated
2021/12/16
AK Scientific
Product number
1037CB
Product name
Nocardamine
Packaging
1mg
Price
$255
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CN2-0150-M005
Product name
Nocardamine
Purity
≥95%(HPLC)
Packaging
5mg
Price
$480
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019192
Product name
NOCARDAMINE
Purity
95.00%
Packaging
5MG
Price
$515.55
Updated
2021/12/16
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NOCARDAMINE Chemical Properties,Usage,Production

Description

Nocardamine is a ferrioxamine siderophore that has been found in Streptomyces and has diverse biological activities. It chelates iron in a chrome azurol S assay (IC50 = 9.9 μM). Nocardamine inhibits M. smegmatis and M. bovis biofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron. It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively). Nocardamine also induces morphological changes in BM-N4 insect cells.

Uses

Nocardamine is a cyclic siderophore.

Definition

ChEBI: A cyclic hydroxamic acid siderophore that is produced by several bacterial species and exhibits antitumour activity.

storage

+4°C

References

Normant et al. (2020), Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa: Exclusive Involvement of the FoxA Outer Membrane Transporter; ACS Chem. Biol. 15 2741 Ueki et al. (2009), Nocardamin Production by Streptomyces avermitilis; Actinomycetologica 23 34 Yan et al. (2021), Ferroptosis: mechanisms and links with diseases; Signal Transduct. Target Ther. 6 49 Kalinovskaya et al. (2011), Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activity; Res. 166 654 Mahmud et al. (2022), Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809; Molecules 27 2292

NOCARDAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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NOCARDAMINE Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-89903882 13626641628
Email
jiangnan@huidabiotech.com
Country
China
ProdList
3656
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-0571-89903882 15990081639
Email
sunshixuan@huidabiotech.com
Country
China
ProdList
3705
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725
Email
malulu@leyan.com
Country
China
ProdList
39953
Advantage
58

26605-16-3, NOCARDAMINERelated Search:


  • NOCARDAMINE
  • PROFERRIOXAMIN E
  • deferrioxamine E
  • 1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone
  • 6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone
  • Desferri-ferrioxamine E
  • Desferrioxamine E
  • Nocardamin
  • Nocardamine (Deferrioxamine E)
  • 1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-
  • 26605-16-3
  • C27H48N6O9