NOCARDAMINE

Product Name: NOCARDAMINE
CAS No.: 26605-16-3
Chemical Name: NOCARDAMINE
Synonyms: Nocardamin;NOCARDAMINE;deferrioxamine E;PROFERRIOXAMIN E;Desferrioxamine E;Desferri-ferrioxamine E;Nocardamine (Deferrioxamine E);Nocardamine (Deferrioxamine E), Antibiotic agent;1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone;6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone
CBNumber: CB7117055
Molecular Formula: C27H48N6O9
Formula Weight: 600.7
MOL File: 26605-16-3.mol

More

Less

NOCARDAMINE Property

Melting point:: 192-195°
Density: 1.162±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (5 mg/ml)
form: solid
pka: 8?+-.0.20(Predicted)
color: Off-white
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 28745
Product name: Nocardamine
Packaging: 1mg
Price: $109
Updated: 2024/03/01

TRC

Product number: N634083
Product name: Nocardamine
Packaging: 1mg
Price: $205
Updated: 2021/12/16

AK Scientific

Product number: 1037CB
Product name: Nocardamine
Packaging: 1mg
Price: $255
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CN2-0150-M005
Product name: Nocardamine
Purity: ≥95%(HPLC)
Packaging: 5mg
Price: $480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019192
Product name: NOCARDAMINE
Purity: 95.00%
Packaging: 5MG
Price: $515.55
Updated: 2021/12/16

More

Less

NOCARDAMINE Chemical Properties,Usage,Production

Description

Nocardamine is a ferrioxamine siderophore that has been found in Streptomyces and has diverse biological activities. It chelates iron in a chrome azurol S assay (IC₅₀ = 9.9 μM). Nocardamine inhibits M. smegmatis and M. bovis biofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron. It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC₅₀s = 6, 18, 12, and 14 μM, respectively). Nocardamine also induces morphological changes in BM-N4 insect cells.

Uses

Nocardamine is a cyclic siderophore.

Definition

ChEBI: A cyclic hydroxamic acid siderophore that is produced by several bacterial species and exhibits antitumour activity.

storage

+4°C

References

[1] VINCENT NORMANT. Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa: Exclusive Involvement of the FoxA Outer Membrane Transporter[J]. ACS Chemical Biology, 2020, 15 10: 2741-2751. DOI:10.1021/acschembio.0c00535
[2] UEKI M, SUZUKI R, TAKAMATSU S, et al. Nocardamin Production by Streptomyces avermitilis[C]//285 1. 2009: 0. DOI:10.3209/saj.saj230203
[3] HONG-FA YAN. Ferroptosis: mechanisms and links with diseases.[J]. Signal Transduction and Targeted Therapy, 2021, 6 1: 49. DOI:10.1038/s41392-020-00428-9
[4] NATALIYA I. KALINOVSKAYA . Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activity[J]. Microbiological research, 2011, 166 8: Pages 654-661. DOI:10.1016/j.micres.2011.01.004
[5] F. MAHMUD. Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809[J]. Molecules, 2022. DOI:10.3390/molecules27072292

NOCARDAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

NOCARDAMINE Suppliers

CHINA 33 Germany 1 India 2 United States 7 Global 43

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-89903882 18679456698
Email: mingxinzhu@huidabiotech.com
Country: China
ProdList: 2975
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-0571-89903882 15990081639
Email: sunshixuan@huidabiotech.com
Country: China
ProdList: 3705
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

Guangzhou Yaoguang Technology Co., Ltd.

Tel: 13020159086
Email: yangjue@ygfuture.com
Country: China
ProdList: 424
Advantage: 58

Tanmo Quality Inspection Technology Co., Ltd.

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 6043
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2760
Advantage: 58

Adipogen Life Sciences

Tel: 41-6192660-40
Email: info@adipogen.com
Country: China
ProdList: 5293
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Funakoshi Co Ltd

Tel: 81356846296
Email: export@funakoshi.co.jp
Country: China
ProdList: 2347
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49941
Advantage: 58

Shenzhen Campbell Biotechnology Co., Ltd.

Tel: 18028747627
Country: CHINA
ProdList: 191
Advantage: 58

Hangzhou Haofeng Biotechnology Co., Ltd.

Tel: 057186405477
Country: CHINA
ProdList: 184
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Shanghai Silk Dragon Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 3988
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6973
Advantage: 58

Beijing Baiao Innovation Technology Co., Ltd.

Tel: --
Fax: --
Email: 3007606172@qq.com
Country: CHINA
ProdList: 6002
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Beijing Bai Ao Si Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: yangmei@bioneeds.net
Country: CHINA
ProdList: 6999
Advantage: 58

Beijing Dongge Boye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1861586486@qq.com
Country: CHINA
ProdList: 6648
Advantage: 58

Beijing Fubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: info@f-biology.com
Country: CHINA
ProdList: 6170
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Beijing Sizhengbai Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: marketing@4abio.com
Country: CHINA
ProdList: 6401
Advantage: 58

Shenzhen Xinbosheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: service@neobioscience.com
Country: CHINA
ProdList: 6151
Advantage: 58

Shanghai Minmin Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1914109725@qq.com
Country: CHINA
ProdList: 6518
Advantage: 58

26605-16-3, NOCARDAMINERelated Search:

DO264 N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) AZ20 BI 2536 DEFEROXAMINE MESYLATE NOCARDAMINE

NOCARDAMINE

PROFERRIOXAMIN E

deferrioxamine E

1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone

6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone

Desferri-ferrioxamine E

Desferrioxamine E

Nocardamin

Nocardamine (Deferrioxamine E)

1,6,12,17,23,28-Hexaazacyclotritriacontane-2,5,13,16,24,27-hexone, 1,12,23-trihydroxy-

Nocardamine (Deferrioxamine E), Antibiotic agent

26605-16-3

C27H48N6O9