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L-Menthyl acetate

Product Name
L-Menthyl acetate
CAS No.
2623-23-6
Chemical Name
L-Menthyl acetate
Synonyms
FEMA 2668;Brn 2208505;Acetoxymenthane;L-Menthylacetat;Menthyl Acatate;1-MENTHYLACETATE;L-MENTHYL ACETATE;(+)-Isocorynoline;MENTHYL ACETATE, L-;(-)-Menthyl Acetate
CBNumber
CB7117565
Molecular Formula
C12H22O2
Formula Weight
198.3
MOL File
2623-23-6.mol
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L-Menthyl acetate Property

Melting point:
<25 °C
alpha 
-81°(20/D, c=8, C6H6)
Boiling point:
229-230 °C(lit.)
Density 
0.92 g/mL at 25 °C(lit.)
vapor pressure 
45Pa at 20℃
FEMA 
2668 | MENTHYL ACETATE (ISOMER UNSPECIFIED)
refractive index 
n20/D 1.447(lit.)
Flash point:
171 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
Specific Gravity
0.922
color 
Colourless
Odor
at 100.00 %. mentholic minty herbal tea fruity woody floral earthy
Odor Type
mentholic
optical activity
[α]20/D 81°, c = 8 in benzene
Water Solubility 
23.2mg/L at 20℃
JECFA Number
431
Merck 
14,5839
BRN 
2208505
LogP
4.39 at 25℃
CAS DataBase Reference
2623-23-6(CAS DataBase Reference)
EPA Substance Registry System
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- (2623-23-6)
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Safety

Safety Statements 
24/25
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
AI5900000
TSCA 
Yes
HS Code 
2915 39 00
Toxicity
LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W266825
Product name
L-Menthyl acetate
Purity
natural, ≥98%, FCC, FG
Packaging
100g
Price
$75.8
Updated
2024/03/01
Sigma-Aldrich
Product number
W266825
Product name
L-Menthyl acetate
Purity
natural, ≥98%, FCC, FG
Packaging
1kg
Price
$414
Updated
2024/03/01
Sigma-Aldrich
Product number
8.16147
Product name
(R)-(-)-Menthyl acetate
Purity
forsynthesis
Packaging
10ml
Price
$44.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.16147
Product name
(R)-(-)-Menthyl acetate
Purity
forsynthesis
Packaging
100mL
Price
$154
Updated
2024/03/01
Sigma-Aldrich
Product number
45985
Product name
(1R)-(−)-Menthyl acetate
Purity
analytical standard
Packaging
1mL
Price
$180
Updated
2024/03/01
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L-Menthyl acetate Chemical Properties,Usage,Production

Chemical Properties

(1R)-(-)-Menthyl acetate occurs in peppermint oils. It is a colorless liquid with a fresh, fruity, peppermint odor.
(?)-Menthyl acetate is prepared by acetylation of (?)-menthol (e.g., with acetic anhydride). It is used mainly in peppermint flavors and reconstituted peppermint oils, but also to a small extent in perfumery.

Uses

L-Menthyl Acetate, and its derivatives, is used as a penetration enhancers, to enhance the skin permeation of various drugs with differing lipophilicities, such as 5-aminolevulinic acid (ALA), 5-fluorouracil (5-FU), isosorbide dinitrate (ISDN), lidocaine (LD), etc.

Definition

ChEBI: (-)-Menthyl acetate is a p-menthane monoterpenoid.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Taste at 25 ppm

Safety Profile

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

L-Menthyl acetate is produced by direct esterification of racemicMenthol with Acetic acid under azeotropic conditions.

L-Menthyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-Menthyl acetate manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Menthyl Acetate 2623-23-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2024-01-31
Hebei Kingfiner Technology Development Co.Ltd
Product
(1R)-(-)-Menthyl acetate 2623-23-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000kg
Release date
2024-05-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
L-Menthyl acetate 2623-23-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

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