Columbin

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Product Name: Columbin
CAS No.: 546-97-4
Chemical Name: Columbin
Synonyms: Tinosporin;Columbin USP/EP/BP;Columbin, 10 mM in DMSO;Columbin >=95% (LC/MS-ELSD);Columbin, 98%, from limacia sagittata;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione;diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione
CBNumber: CB71246910
Molecular Formula: C20H22O6
Formula Weight: 358.39
MOL File: 546-97-4.mol

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Columbin Property

Melting point:: 190-191℃
alpha: D +52.5° (pyridine)
Boiling point:: 410.82°C (rough estimate)
Density: 1.36
refractive index: 1.4450 (estimate)
storage temp.: -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.03 mg/ml
pka: 12.14±0.70(Predicted)
form: Cryst.
color: White to off-white

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Safety

WGK Germany: 3
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00086
Product name: Columbin
Purity: ≥95% (LC/MS-ELSD)
Packaging: 1mg
Price: $303
Updated: 2024/03/01

Cayman Chemical

Product number: 24105
Product name: Columbin
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 24105
Product name: Columbin
Purity: ≥98%
Packaging: 5mg
Price: $140
Updated: 2024/03/01

Cayman Chemical

Product number: 24105
Product name: Columbin
Purity: ≥98%
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 24105
Product name: Columbin
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

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Columbin Chemical Properties,Usage,Production

Uses

Columbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties.

Definition

ChEBI: Columbin is an organic heterotricyclic compound and an organooxygen compound.

Columbin Preparation Products And Raw materials

Raw materials

Preparation Products

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Columbin Suppliers

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View Lastest Price from Columbin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Columbin 546-97-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-22

Career Henan Chemical Co

Product: (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione 546-97-4
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

546-97-4, ColumbinRelated Search:

12-O-Tiglylphorbol-13 -isobutyrate 10-Deacetylbaccatin III β-Elemonic Acid DARUTOSIDE dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate siegesmethyethericacid Carboxyatractyloside (S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid (CIS)-8-METHYLNON-6-ENOIC ACID Columbin Isopropyl-cyclohexanecarboxylic acid ALLYLCYCLOHEXANE ACETATE ISOBUTYL VINYLACETATE (S)-(+)-HEXAHYDROMANDELIC ACID METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE 2H-PYRAN-2-ONE, 3-ETHYLTETRAHYDRO-, (R)- 2-PROPENYL 3,5,5-TRIMETHYLHEXANOATE tetrahydro-3-pentyl-2H-pyran-2-one

(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione

Columbin, 98%, from limacia sagittata

(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione

(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione

Tinosporin

(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione

(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione

1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R,4R,4aR,6aR,9S,10aS,10bS)-

Columbin >=95% (LC/MS-ELSD)

Columbin USP/EP/BP

(2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione

diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit

Columbin, 10 mM in DMSO

546-97-4

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