ChemicalBook > CAS DataBase List > 2-Oxazolidone

2-Oxazolidone

Product Name
2-Oxazolidone
CAS No.
497-25-6
Chemical Name
2-Oxazolidone
Synonyms
oxazolidin-2-one;Oxazolidine;2-OXAZOLIDINONE;Oxazolidone;NSC 35382;2-Oxazolinone;2-OXAZOLIDIONE;2-OX;2-OxazoL;NSC 38240
CBNumber
CB7141597
Molecular Formula
C3H5NO2
Formula Weight
87.08
MOL File
497-25-6.mol
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2-Oxazolidone Property

Melting point:
83-87 °C(lit.)
Boiling point:
220 °C48 mm Hg(lit.)
Density 
1.2736 (rough estimate)
refractive index 
1.4940 (estimate)
Flash point:
220°C/48mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly, Heated), Methanol (Slightly)
pka
12.78±0.20(Predicted)
form 
Crystals or Powder
color 
Off-white to yellow-beige
Water Solubility 
Soluble in water.
BRN 
106251
CAS DataBase Reference
497-25-6(CAS DataBase Reference)
NIST Chemistry Reference
Oxazolidin-2-one(497-25-6)
EPA Substance Registry System
2-Oxazolidinone (497-25-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36-43-40-36/37/38
Safety Statements 
26-36/37-37-36
WGK Germany 
3
RTECS 
RQ2450000
TSCA 
Yes
HS Code 
29322980
Toxicity
TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O9409
Product name
2-Oxazolidinone
Purity
98%
Packaging
5g
Price
$36.7
Updated
2024/03/01
Sigma-Aldrich
Product number
O9409
Product name
2-Oxazolidinone
Purity
98%
Packaging
25g
Price
$48.4
Updated
2024/03/01
TCI Chemical
Product number
O0188
Product name
2-Oxazolidone
Purity
>98.0%(GC)
Packaging
25g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
O0188
Product name
2-Oxazolidone
Purity
>98.0%(GC)
Packaging
100g
Price
$90
Updated
2024/03/01
Alfa Aesar
Product number
A14543
Product name
2-Oxazolidinone, 99%
Packaging
25g
Price
$39.65
Updated
2024/03/01
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2-Oxazolidone Chemical Properties,Usage,Production

Chemical Properties

off-white to yellow-beige crystals or powder

Uses

An oxazole derivative used as an antibiotic. It is also used in the preparation of compounds with antitumor activity. A metabolite of Furazolidone (F864100).

Uses

As an oxazole derivative used as an antibiotic, 2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100).

Definition

ChEBI: An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise it from *benzene, dichloroethane, CHCl3 or EtOH. It is a cyclic urethane, and as such it is not very stable. [Katritzky et al. J Chem Soc Perkin II 145 1990, Beilstein 27 H 135, 27 II 259, 27 III/IV 2516.]

2-Oxazolidone Preparation Products And Raw materials

Raw materials

Monoethanolamine

Preparation Products

Lomustine N,N'-bis-(2-Chloroethyl)urea 3-AMINO-2-OXAZOLIDINONE Furazolidone
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2-Oxazolidone Suppliers

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View Lastest Price from 2-Oxazolidone manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-Oxazolidone 497-25-6
Price
US $25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-11
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Oxazolidone 497-25-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-13
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Oxazolidone 497-25-6
Price
US $10.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
10 ton
Release date
2024-08-20

497-25-6, 2-Oxazolidone Related Search:

Oxadixyl Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 3-PHENYL-2-OXAZOLIDINONE 3-(2'-HYDROXYETHYL)-2-OXAZOLIDONE,N-Hydroxyethyl-2-oxazolidone 3-((5-Nitrofurylidene)amino)-2-oxazolidone,3-(5'-Nitrofurfuralamino)-2-oxazolidone,3-(5’-nitrofurfuralamino)-2-oxazolidon 5-CHLOROMETHYL-2-OXAZOLIDINONE (S)-(+)-4-PHENYL-2-OXAZOLIDONE (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone S-4-Isopropyl-2-oxazolidone 3-TRIMETHYLSILYL-2-OXAZOLIDONE 3-AMINO-2-OXAZOLIDINONE 5,5-Dimethyloxazolidine-2,4-dione (R)-(+)-4-BENZYL-2-OXAZOLIDONE 3-Methyl-2-oxazolidone 3-Acetyl-1-chlorocarbonyl-2-imidazolidone 5-methylthiomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone N-PROPIONYL-(4S,5R)-4-METHYL- 5-PHENYL-2-OXAZOLIDINONE

  • 2-Oxotetrahydro-1,3-oxazole
  • 2-Oxazolinone
  • 2-Oxazolidone,98%
  • 2-Oxazolidone, 98% 100GR
  • 2-Oxazolidone, 98% 25GR
  • 2-Oxo-1,3-oxazolidine
  • NSC 35382
  • NSC 38240
  • 2-Oxazolidinone≥ 99%(GC)
  • 2H-oxazol-2-id-4-one
  • (2-hydroxyethyl)-carbamicacigamma-lactone
  • 1,3-Oxazolidin-2-one
  • 2-Oxazolidine
  • Carbamic acid, (2-hydroxyethyl)-, gamma-lactone
  • Oxazolidine
  • Oxazolidone
  • 2-OX
  • 2-OXAZOLIDONE
  • 2-OXAZOLIDINONE
  • oxazolidin-2-one
  • 2-Oxazolidinone,99%
  • 2-OXAZOLIDIONE
  • (2-hydroxyethyl)-carbamic acid gamma-lactone
  • 2-OXAZOLIDINONE 98%
  • 2-OxazoL
  • 2-Oxazolidone&gt
  • 2-Oxazolidinone, 98%, for synthesis
  • Levetiracetam Impurity 45
  • 2-Oxazolidinone (7CI, 8CI, 9CI, ACI)
  • (4S,4′S)-4,4′-[[4-(dimethylamino)butane-1,1-diyl]bis[[3-[2-(dimethylamino)ethyl]-1H-indole-2,5-diyl]methylene]]bis(1,3-oxazolidin-2-one)
  • 497-25-6
  • 495-25-6
  • C3H5NO2
  • Oxazolines/Oxazolidines
  • Heterocyclic Building Blocks
  • Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Oxazolines/Oxazolidines
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocyclic Compounds