3-Bromo-1,5-naphthyridine
- Product Name
- 3-Bromo-1,5-naphthyridine
- CAS No.
- 17965-71-8
- Chemical Name
- 3-Bromo-1,5-naphthyridine
- Synonyms
- 3-broMo-1;5-naphthyridine;3-Bromo-1,5phthyridine;3-bromo-1, 5-naphthidine;3-bromo-1,5-naphthyridine;1,5-Naphthyridine,3-bromo-
- CBNumber
- CB71457099
- Molecular Formula
- C8H5BrN2
- Formula Weight
- 209.04
- MOL File
- 17965-71-8.mol
3-Bromo-1,5-naphthyridine Property
- Boiling point:
- 289 °C
- Density
- 1.656
- Flash point:
- 129 °C
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.43±0.10(Predicted)
- Appearance
- Brown to black Solid
- InChI
- InChI=1S/C8H5BrN2/c9-6-4-8-7(11-5-6)2-1-3-10-8/h1-5H
- InChIKey
- DQTDPFYKQAQVJU-UHFFFAOYSA-N
- SMILES
- N1C2C(=NC=CC=2)C=C(Br)C=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FB140801
- Product name
- 3-Bromo-1,5-naphthyridine
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FB140801
- Product name
- 3-Bromo-1,5-naphthyridine
- Packaging
- 250mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FB140801
- Product name
- 3-Bromo-1,5-naphthyridine
- Packaging
- 500mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- W3903
- Product name
- 3-Bromo-1,5-naphthyridine
- Packaging
- 1g
- Price
- $261
- Updated
- 2021/12/16
- Product number
- FB140801
- Product name
- 3-Bromo-1,5-naphthyridine
- Packaging
- 1g
- Price
- $418.75
- Updated
- 2021/12/16
3-Bromo-1,5-naphthyridine Chemical Properties,Usage,Production
Synthesis
254-79-5
17965-71-8
General procedure for the synthesis of 3-bromo-1,5-naphthyridine from 1,5-naphthyridine: To a 10 mL solution of glacial acetic acid containing compound 4 (2.7 g, 20.76 mmol) and NaOAc (3.41 g, 41.52 mmol), stirred at 85 °C, 1 M of bromine in acetic acid (35 mL) was slowly added, and the reaction lasted for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the acetic acid was removed by vacuum concentration. The product was purified by column chromatography (petroleum ether/ethyl acetate = 2:1) to give compound 5 (2.36 g, 55% yield) as a white solid. Melting point: 107-108 °C (literature value: 108-109 °C).1H NMR (400 MHz, CDCl3): δ 8.96 (d, J = 2.1 Hz, 2H), 8.56 (s, 1H), 8.36 (d, J = 8.5 Hz, 1H), 7.69-7.56 (m, 1H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 16, p. 3251 - 3255
[2] Patent: WO2011/149937, 2011, A1. Location in patent: Page/Page column 39; 75
[3] Patent: WO2013/78441, 2013, A1. Location in patent: Paragraph 00143; 00305
[4] Patent: WO2008/82487, 2008, A2. Location in patent: Page/Page column 108
[5] Patent: WO2011/15343, 2011, A1. Location in patent: Page/Page column 40
3-Bromo-1,5-naphthyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-1,5-naphthyridine Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 3-Bromo-1,5-naphthyridine manufacturers
- Product
- 3-Bromo-1,5-naphthyridine 17965-71-8
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-08