3-((2,2,2- trifluoroethyl)thio)aniline
- Product Name
- 3-((2,2,2- trifluoroethyl)thio)aniline
- CAS No.
- 1445684-99-0
- Chemical Name
- 3-((2,2,2- trifluoroethyl)thio)aniline
- Synonyms
- NA12878;CarolGold;PBA-PEG-AC;WKPep Erasin;Palm-Glu-OtBu;Fmoc-D-Ala-Ala-OH;CarolGold (Lutein);Magnolol & Honokiol;BOC-(D)-HIS(TRT)-AIB;Octa(OtBu)-D-Glu-OtBu
- CBNumber
- CB71459710
- Molecular Formula
- C8H8F3NS
- Formula Weight
- 207.22
- MOL File
- 1445684-99-0.mol
3-((2,2,2- trifluoroethyl)thio)aniline Property
- InChI
- InChI=1S/C8H8F3NS/c9-8(10,11)5-13-7-3-1-2-6(12)4-7/h1-4H,5,12H2
- InChIKey
- KMYQCBMXXMOPSD-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=CC(SCC(F)(F)F)=C1
N-Bromosuccinimide Price
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- FAA7750
- Product name
- Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
- Packaging
- 1g
- Price
- $607.5
- Updated
- 2021/12/16
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 5g
- Price
- $900
- Updated
- 2021/12/16
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 25g
- Price
- $2000
- Updated
- 2021/12/16
- Product number
- FAA7750
- Product name
- Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
- Packaging
- 5G
- Price
- $2160
- Updated
- 2021/12/16
3-((2,2,2- trifluoroethyl)thio)aniline Chemical Properties,Usage,Production
Uses
3-((2,2,2-trifluoroethyl)thio)aniline can be used as an intermediate in pharmaceutical research.
Synthesis
To a solution of 3-aminobenzenethiol (4.43 g, 35.4 mmol) in THF (225 mL) was added sodium hydride (1.77 g, 44.3 mmol) at 0 °C and stirred for 30 min. Then, 2,2,2-trifluoroethyl 4- methylbenzenesulfonate (9.0 g, 35.4 mmol) was added and the reaction mixture was stirred for 18 h. The reaction mixture was quenched with water (20 mL) and extracted with EtOAc (2x50 mL). The combined organic extracts were washed with water, dried over Na2SO4, fdtered, and concentrated under reduced pressure. The crude residue was purified by flash chromatography through a Redi-Sep pre-packed silica gel column, eluting with a gradient of 5 % to 10 % EtOAc in hexanes, to give 3-((2,2,2- trifluoroethyl)thio)aniline (5 g, 68 % yield) as a pale brown oil.
3-((2,2,2- trifluoroethyl)thio)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
3-((2,2,2- trifluoroethyl)thio)aniline Suppliers
- Tel
- 028-82550498 19102685862
- Fax
- 086-28-82550468
- sales@pu-kang.com
- Country
- China
- ProdList
- 485
- Advantage
- 58
- Tel
- 028-82729560 18030702676
- Fax
- 028-82729560
- sales@yuehepharm.com
- Country
- China
- ProdList
- 179
- Advantage
- 58
- Tel
- 0514-86654616 15366892466
- greenchem@tzglmk.com
- Country
- China
- ProdList
- 498
- Advantage
- 56
- Tel
- 3429815786 13301662590
- Fax
- +86-21-51619052
- Mandy@ATKchemical.com
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 15076683720
- Fax
- 022-23754520
- klq@cw-bio.com
- Country
- China
- ProdList
- 4602
- Advantage
- 55
- Tel
- 0510-83583050 13771062561
- Fax
- 0510-83583039
- willsun@peptide-search.com
- Country
- China
- ProdList
- 6716
- Advantage
- 58
- Tel
- 0755-89880280
- Fax
- 0755-89880280
- 3004662104@qq.com
- Country
- China
- ProdList
- 1829
- Advantage
- 58
- Tel
- 0571-87213919
- Fax
- 0571-87213919
- Eric@peptidego.com
- Country
- China
- ProdList
- 6756
- Advantage
- 58
- Tel
- 020-81716320 17788709170
- Fax
- 020-81716319
- Sales@pipitech.com
- Country
- China
- ProdList
- 2649
- Advantage
- 58
- Tel
- 0755-26659310 15915457431
- Fax
- 0755-26659310
- linkunsheng@szreadline.com
- Country
- China
- ProdList
- 110
- Advantage
- 58
View Lastest Price from 3-((2,2,2- trifluoroethyl)thio)aniline manufacturers
- Product
- 4-Chluoro-2-bromotoluene 1445684-99-0
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 98%
- Supply Ability
- 1kg,2kg,100kg
- Release date
- 2019-07-09