ChemicalBook > CAS DataBase List > 3-((2,2,2- trifluoroethyl)thio)aniline
3-((2,2,2- trifluoroethyl)thio)aniline
- Product Name
- 3-((2,2,2- trifluoroethyl)thio)aniline
- CAS No.
- 1445684-99-0
- Chemical Name
- 3-((2,2,2- trifluoroethyl)thio)aniline
- Synonyms
- NA12878;CarolGold;WKPep Erasin;Palm-Glu-OtBu;Fmoc-D-Ala-Ala-OH;CarolGold (Lutein);Magnolol & Honokiol;BOC-(D)-HIS(TRT)-AIB;Octa(OtBu)-D-Glu-OtBu;Boc-D-His(Trt)-Aib-OH
- CBNumber
- CB71459710
- Molecular Formula
- C8H8F3NS
- Formula Weight
- 207.22
- MOL File
- 1445684-99-0.mol
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3-((2,2,2- trifluoroethyl)thio)aniline Property
- InChI
- InChI=1S/C8H8F3NS/c9-8(10,11)5-13-7-3-1-2-6(12)4-7/h1-4H,5,12H2
- InChIKey
- KMYQCBMXXMOPSD-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=CC(SCC(F)(F)F)=C1
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N-Bromosuccinimide Price
chempep
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- FAA7750
- Product name
- Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
- Packaging
- 1g
- Price
- $607.5
- Updated
- 2021/12/16
chempep
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 5g
- Price
- $900
- Updated
- 2021/12/16
chempep
- Product number
- 181931
- Product name
- Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
- Packaging
- 25g
- Price
- $2000
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- FAA7750
- Product name
- Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH
- Packaging
- 5G
- Price
- $2160
- Updated
- 2021/12/16
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3-((2,2,2- trifluoroethyl)thio)aniline Chemical Properties,Usage,Production
Uses
3-((2,2,2-trifluoroethyl)thio)aniline can be used as an intermediate in pharmaceutical research.
Synthesis
To a solution of 3-aminobenzenethiol (4.43 g, 35.4 mmol) in THF (225 mL) was added sodium hydride (1.77 g, 44.3 mmol) at 0 °C and stirred for 30 min. Then, 2,2,2-trifluoroethyl 4- methylbenzenesulfonate (9.0 g, 35.4 mmol) was added and the reaction mixture was stirred for 18 h. The reaction mixture was quenched with water (20 mL) and extracted with EtOAc (2x50 mL). The combined organic extracts were washed with water, dried over Na2SO4, fdtered, and concentrated under reduced pressure. The crude residue was purified by flash chromatography through a Redi-Sep pre-packed silica gel column, eluting with a gradient of 5 % to 10 % EtOAc in hexanes, to give 3-((2,2,2- trifluoroethyl)thio)aniline (5 g, 68 % yield) as a pale brown oil.
3-((2,2,2- trifluoroethyl)thio)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
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3-((2,2,2- trifluoroethyl)thio)aniline Suppliers
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View Lastest Price from 3-((2,2,2- trifluoroethyl)thio)aniline manufacturers
Career Henan Chemical Co
- Product
- 4-Chluoro-2-bromotoluene 1445684-99-0
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 98%
- Supply Ability
- 1kg,2kg,100kg
- Release date
- 2019-07-09
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