Clopidol Property

Melting point:

>320℃

Boiling point:

318.4±37.0 °C(Predicted)

Density 

1.2494 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Aqueous Base (Slightly), Methanol (Slightly, Heated)

form 

Solid

pka

5.50±0.33(Predicted)

color 

White to Off-White

Water Solubility 

40mg/L(temperature not stated)

Stability:

Hygroscopic

InChIKey

QCMHHYSPKNVXLR-UHFFFAOYSA-N

CAS DataBase Reference

2971-90-6(CAS DataBase Reference)

EPA Substance Registry System

Clopidol (2971-90-6)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

OEB

B

OEL

TWA: 10 mg/m3 (total), STEL: 20 mg/m3 (total)

WGK Germany 

2

RTECS 

UU7711500

HS Code 

29333990

Hazardous Substances Data

2971-90-6(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 18 g/kg (Plisek)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Clopidol Chemical Properties,Usage,Production

Description

The drug methylchlorpindol is used for the prevention of coccidiosis in poultry.

Description

Clopidol is a coccidiostat. It prevents mortality of chickens infected with the parasites E. tenella, E. necatrix, E. acervuline, E. mivati, E. brunetti, and E. maxima. It has antimalarial activity against P. berghei in mice and P. cynomologi in rhesus macaques. Clopidol is a potential contaminant in food poultry. Formulations containing clopidol have been used in the prevention of coccidiosis in chickens.

Chemical Properties

Clopidol is a white to light brown powder.

Uses

GABA Cl channel agonist, antiparasitic

Uses

An antibiotic used in veterinary medicine as a coccidiostat in poultry. Showed low order of acute and chronic toxicity in animals.

Uses

An antiprotozoal agent.

Definition

A penta-substituted pyridine derivative.

General Description

White to light-brown, crystalline solid. Mp: 320°C. Practically insoluble in water. Administered to poultry to prevent the growth of pathogenic parasites.

Reactivity Profile

Clopidol is a non-combustible as a solid, but dust may burn rapidly or explode when mixed with air and ignited.

Hazard

Toxic. Mutagenic effects. Questionable carcinogen. Clopyralid.

Contact allergens

This drug is used for the prevention of coccidiosis in poultry.

Safety Profile

A nuisance dust. When heated to decomposition it emits very toxic fumes of Cland NOx.

Potential Exposure

Those engaged in formulation, application or manufacture of this veterinary antibiotic. Used as a pharmaceutical and as feed and food additive

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with clopidolyou should be trained on its proper handling and storage.Store in tightly closed containers in a cool, well-ventilatedarea.

Shipping

UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Noncombustible solid, but dust may explode in cloud form. Contact with strong oxidizers may cause a fire or explosion hazard

Waste Disposal

Dispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.