2-CHLORO-6-NITROQUINOLINE
- Product Name
- 2-CHLORO-6-NITROQUINOLINE
- CAS No.
- 29969-57-1
- Chemical Name
- 2-CHLORO-6-NITROQUINOLINE
- Synonyms
- 2-chlor-6-nitro-chinolin;2-CHLORO-6-NITROQUINOLINE;Quinoline, 2-chloro-6-nitro-
- CBNumber
- CB71490890
- Molecular Formula
- C9H5ClN2O2
- Formula Weight
- 208.6
- MOL File
- 29969-57-1.mol
2-CHLORO-6-NITROQUINOLINE Property
- Melting point:
- 236-237 ºC
- Boiling point:
- 363.4±22.0 °C(Predicted)
- Density
- 1.484
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.42±0.43(Predicted)
- form
- solid
- color
- Grey
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR927639
- Product name
- 2-Chloro-6-nitroquinoline
- Purity
- 97%
- Packaging
- 250mg
- Price
- $72
- Updated
- 2021/12/16
- Product number
- OR927639
- Product name
- 2-Chloro-6-nitroquinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $158
- Updated
- 2021/12/16
- Product number
- 118923
- Product name
- 2-Chloro-6-nitroquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- OR927639
- Product name
- 2-Chloro-6-nitroquinoline
- Purity
- 97%
- Packaging
- 5g
- Price
- $472
- Updated
- 2021/12/16
- Product number
- W5240
- Product name
- 2-Chloro-6-nitroquinoline
- Packaging
- 5g
- Price
- $531
- Updated
- 2021/12/16
2-CHLORO-6-NITROQUINOLINE Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
Synthesis
22246-16-8
29969-57-1
Step 4 Synthesis of 2-chloro-6-nitroquinoline: To a solution of 6-nitro-3,4-dihydroquinolin-2(1H)-one (8.2 g, 41.9 mmol) in benzene (150 mL) was added DDQ (9.6 g, 42.5 mmol) and phosphorus triclosan (20.5 mL) sequentially, and the homogeneity of the reaction system was maintained during dropwise addition. The reaction mixture was heated to 90 °C with continuous stirring for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was subsequently quenched by slowly pouring into 500 mL of ice water. The pH was adjusted to 7 with 4N NaOH solution. extraction was carried out with ethyl acetate (3 x 1 L) and the organic phases were combined. The organic phase was concentrated under reduced pressure to give 8.4 g of 2-chloro-6-nitroquinoline in yellow solid form in 95% yield.
References
[1] Heterocycles, 1998, vol. 48, # 12, p. 2637 - 2641
[2] Patent: US2007/27184, 2007, A1. Location in patent: Page/Page column 18; 25
[3] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 20, p. 5270 - 5274
[4] Patent: KR101576386, 2015, B1. Location in patent: Paragraph 0190; 0193-0194
2-CHLORO-6-NITROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-6-NITROQUINOLINE Suppliers
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
- Tel
- --
- Fax
- --
- enamine@enamine.net
- Country
- Ukraine
- ProdList
- 6216
- Advantage
- 67
View Lastest Price from 2-CHLORO-6-NITROQUINOLINE manufacturers
- Product
- 2-chloro-6-nitroquinoline 29969-57-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 500kgs
- Release date
- 2024-05-15
- Product
- 2-CHLORO-6-NITROQUINOLINE 29969-57-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-12-18