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2-(2-Methoxyethoxy)ethanamine

Product Name
2-(2-Methoxyethoxy)ethanamine
CAS No.
31576-51-9
Chemical Name
2-(2-Methoxyethoxy)ethanamine
Synonyms
MeO-PEG2-NH2;m-PEG2-amine;NH2-PEG2-OME;MeO-EG(2)-NH2;Methyl-PEG2-amine;2-(2-Methoxyethoxy)ethanamine;2-(2-Methoxyethoxy)ethylamine;mPEG2-NH2;EthanaMine, 2-(2-Methoxyethoxy)-;2-(2-Methoxyethoxy)ethoxy]ethenamine
CBNumber
CB71510916
Molecular Formula
C5H13NO2
Formula Weight
119.16
MOL File
31576-51-9.mol
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2-(2-Methoxyethoxy)ethanamine Property

Boiling point:
163.7±15.0 °C(Predicted)
Density 
0.934±0.06 g/cm3(Predicted)
refractive index 
n/D 1.429
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
8.75±0.10(Predicted)
form 
Solid
color 
Colourless to Off-White
Stability:
Hygroscopic
InChI
InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3
InChIKey
QWCGXANSAOXRFE-UHFFFAOYSA-N
SMILES
C(N)COCCOC
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Safety

RIDADR 
3265
HazardClass 
8
PackingGroup 
HS Code 
2922190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901159
Product name
2-(2-Methoxyethoxy)ethanamine
Purity
≥95%
Packaging
5G
Price
$237
Updated
2025/07/31
TRC
Product number
M262910
Product name
2-(2-Methoxyethoxy)ethanamine
Packaging
250mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-W008429
Product name
m-PEG2-Amine
Purity
>97.0%
Packaging
50mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-W008429
Product name
m-PEG2-Amine
Purity
>97.0%
Packaging
100mg
Price
$59
Updated
2021/12/16
ChemScene
Product number
CS-W008429
Product name
m-PEG2-Amine
Purity
>97.0%
Packaging
250mg
Price
$93
Updated
2021/12/16
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2-(2-Methoxyethoxy)ethanamine Chemical Properties,Usage,Production

Description

m-PEG2-amine is a PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

2-(2-Methoxyethoxy)ethanamine is a reactant in the preparation of cyclopeptoids, a phase-transfer catalyst.

Synthesis

179820-15-6

31576-51-9

2.2.1.3 Synthesis of 2-(2-methoxyethoxy)ethylamine (2d) A mixture of N-[2-(2-methoxyethoxy)ethyl]phthalimide (2c) (27 mmol) and hydrazine monohydrate (43 mmol) in ethanol (30 mL) was refluxed for 3 hours at 100 °C. Upon completion of the reaction, the mixture was cooled to room temperature, filtered, and the filtrate was evaporated. Acetone (50 mL) was added to the residue and the precipitate was filtered. Subsequently, the filtrate was concentrated under reduced pressure to give an orange colored oil 2d in 62% yield. 1H NMR (500 MHz, CDCl3): δ 1.83 (s, 1H), 2.00 (s, 1H), 2.15 (s, 1H), 2.87 (t, J = 5.3 Hz, 1H), 3.35-3.39 (m, 2H), 3.41 (t, J = 6.4 Hz, 1H), 3.50 (t, J = 5.3 Hz, 1H) 3.52-3.55 (m, 2H), 3.60 (dd, J = 5.7, 3.3 Hz, 1H), 3.64 (dd, J = 5.6, 3.8 Hz, 1H), 3.73 (t, J = 6.5 Hz, 1H) ppm; HR ESI-MS (in MeOH): m/z [M + H]+ calcd. 120.0973, found 120.1047. found 120.1047.

IC 50

Cleavable Linker; PEGs

References

[1] Journal of Organic Chemistry, 2011, vol. 76, # 6, p. 1683 - 1691
[2] Journal of Organic Chemistry, 2010, vol. 75, # 3, p. 598 - 610
[3] Inorganica Chimica Acta, 2016, vol. 452, p. 159 - 169
[4] Patent: WO2009/109035, 2009, A1. Location in patent: Page/Page column 57-58

2-(2-Methoxyethoxy)ethanamine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Methoxyethoxy)ethanamine Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74
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View Lastest Price from 2-(2-Methoxyethoxy)ethanamine manufacturers

LAURENT
Product
2-(2-methoxyethoxy)ethanamine 31576-51-9
Price
US $1629.00/g
Min. Order
0.5g
Purity
98%
Supply Ability
300kg
Release date
2025-11-15
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
m-PEG2-Amine 31576-51-9
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-06
Shaanxi Dideu Medichem Co. Ltd
Product
2-(2-Methoxyethoxy)ethanamine 31576-51-9
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-20

31576-51-9, 2-(2-Methoxyethoxy)ethanamineRelated Search:


  • 2-(2-Methoxyethoxy)ethanamine
  • MeO-EG(2)-NH2
  • EthanaMine, 2-(2-Methoxyethoxy)-
  • Methyl-PEG2-amine
  • mPEG<sub>2</sub>-NH<sub>2</sub>
  • m-PEG2-amine
  • Di(ethylene glycol) methyl ether amine
  • 2-(2-Methoxyethoxy)ethylamine
  • NH2-PEG2-OME
  • 2-(2-Methoxyethoxy)ethoxy]ethenamine
  • MeO-PEG2-NH2
  • 2-(2-Methoxyethoxy)ethanamine , m-PEG2-Amine
  • 31576-51-9
  • MeO-PEG-NH2
  • peg