ChemicalBook > CAS DataBase List > 6-bromo-4-chlorocinnoline

6-bromo-4-chlorocinnoline

Product Name
6-bromo-4-chlorocinnoline
CAS No.
68211-15-4
Chemical Name
6-bromo-4-chlorocinnoline
Synonyms
6-bromo-4-chlorocinnoline;Cinnoline, 6-broMo-4-chloro-;6-bromo-4-chlorocinnoline - [B24879]
CBNumber
CB71518725
Molecular Formula
C8H4BrClN2
Formula Weight
243.49
MOL File
68211-15-4.mol
More
Less

6-bromo-4-chlorocinnoline Property

Melting point:
127-128℃
Boiling point:
359.6±45.0 °C(Predicted)
Density 
1.762
storage temp. 
Storage temp. -20°C
pka
-1.08±0.10(Predicted)
Appearance
Light yellow to light brown Solid
InChI
InChI=1S/C8H4BrClN2/c9-5-1-2-8-6(3-5)7(10)4-11-12-8/h1-4H
InChIKey
WAKDQKOZUBTOEX-UHFFFAOYSA-N
SMILES
N1=C2C(C=C(Br)C=C2)=C(Cl)C=N1
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
0513AC
Product name
6-Bromo-4-chlorocinnoline
Packaging
250mg
Price
$451
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0359724
Product name
6-BROMO-4-CHLOROCINNOLINE
Purity
95.00%
Packaging
5MG
Price
$503.66
Updated
2021/12/16
Matrix Scientific
Product number
143708
Product name
6-Bromo-4-chlorocinnoline
Purity
95%
Packaging
1g
Price
$903
Updated
2021/12/16
Matrix Scientific
Product number
143708
Product name
6-Bromo-4-chlorocinnoline
Purity
95%
Packaging
5g
Price
$2709
Updated
2021/12/16
SynChem
Product number
SC-25784
Product name
6-Bromo-4-chlorocinnoline
Purity
90+%
Packaging
1g
Price
$580
Updated
2021/12/16
More
Less

6-bromo-4-chlorocinnoline Chemical Properties,Usage,Production

Synthesis

876-88-0

68211-15-4

General procedure for the synthesis of 4-chloro-6-bromocinnoline from 6-bromocinnolin-4-ol: Thionyl chloride (3 mL) and N,N-dimethylformamide (30 μL) were sequentially added to 6-bromoquinolin-4(1H)-one (300 mg, 1.33 mmol), and the reaction mixture was heated to reflux for 30 min. After completion of the reaction, the reaction solution was concentrated under reduced pressure and saturated aqueous sodium bicarbonate was added to the residue and extracted with ethyl acetate. The organic layers were combined, washed with saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate, filtered and distilled under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford 4-chloro-6-bromocinnoline (288 mg, 89% yield) as a yellow solid.

References

[1] Patent: JP6378918, 2018, B2. Location in patent: Paragraph 0721; 0724
[2] Patent: US2015/259331, 2015, A1. Location in patent: Paragraph 0192
[3] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 20, p. 6832 - 6846
[4] Patent: US2003/187026, 2003, A1
[5] Journal of the Chemical Society, 1950, p. 384,389

6-bromo-4-chlorocinnoline Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-bromo-4-chlorocinnoline Suppliers

China 53 United States 6 Global 59
Xi'an Jurenhexin Pharmaceutical Technology Co., Ltd
Tel
029-86518151 13629269978
Email
jurenhexin0528@126.com
Country
China
ProdList
102
Advantage
58
Zaozhuang Benefit Chemical Co., Ltd.
Tel
0531-69958783 15508681609
Fax
0531-69958783
Email
1948129184@qq.com
Country
China
ProdList
205
Advantage
60
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Wuhan ariel chemical Co., LTD.
Tel
18986259541
Fax
027-87840182
Email
sales@3stc.com
Country
China
ProdList
3764
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
shanghai cooperpharm co.,LTD .
Tel
+86-021-58975553
Fax
+86-021-58975554
Email
sales@cooperpharm.com
Country
China
ProdList
1210
Advantage
56
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
inan new medical technology co., LTD
Tel
0531-; 18954137585
Fax
1939458511
Email
1939458511@qq.com
Country
China
ProdList
294
Advantage
58
Shanghai Sealing Biotechnology Co. Ltd..
Tel
15721176654
Email
1815535157@qq.com
Country
China
ProdList
881
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
ROSEWA HOLDING GROUP CO.,LIMITED
Tel
+86-023-62871537
Email
sales@rosewachem.com
Country
China
ProdList
2803
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Allfluoro pharmaceutical co. ltd.
Tel
+86-400-0216110 +86-15958047586
Fax
0086-21-33275002
Email
sales@allfluoro.com
Country
China
ProdList
11385
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
Advantage
58
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822 18737195735
Fax
QQ:483339295
Email
483339295@qq.com
Country
China
ProdList
7587
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907
Fax
021-64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
9381
Advantage
58
Shanghai Xuerong Chemical Technology Co., LTD
Tel
18201727566
Fax
QQ:230497258
Email
230497258@qq.com
Country
China
ProdList
513
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Email
2853979819@qq.com
Country
China
ProdList
9998
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-63373950 17392213970
Email
1052@dideu.com
Country
China
ProdList
9998
Advantage
58
Suzhou Yueheng Pharmaceutical Technology Co., Ltd.
Tel
15962211760
Email
2665833871@qq.com
Country
China
ProdList
808
Advantage
58
Jiaxing Deyi Chemical Co., Ltd
Tel
0573-85866609 13588473046
Email
824930988@qq.com
Country
China
ProdList
7865
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
sales@pharmablock.com
Country
China
ProdList
7268
Advantage
58
Hangzhou Bingochem Co., Ltd.
Tel
0571-8512-5372
Email
sales@bingochem.com
Country
China
ProdList
21669
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59101766 13125137661
Email
2853877621@qq.com
Country
China
ProdList
7979
Advantage
58
Beijing Born Pharmaceutical Co., Ltd.
Tel
13261021908
Email
1198872622@qq.com
Country
China
ProdList
909
Advantage
55
shanghai honghe yiyao
Tel
18352536981
Email
653603901@qq.com
Country
China
ProdList
477
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Email
sales@coreychem.com
Country
China
ProdList
29847
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
33024
Advantage
60
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49934
Advantage
58
PT CHEM GROUP LIMITED
Tel
+86-85511178;
Email
peter68@ptchemgroup.com
Country
China
ProdList
35425
Advantage
58
More
Less

View Lastest Price from 6-bromo-4-chlorocinnoline manufacturers

Career Henan Chemical Co
Product
6-bromo-4-chlorocinnoline 68211-15-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20tons
Release date
2019-09-05

68211-15-4, 6-bromo-4-chlorocinnolineRelated Search:

CINNOLINE HYDROCHLORIDE 98 4-CHLORO-CINNOLINE 6-bromocinnoline 6-bromo-4-chlorocinnoline

  • 6-bromo-4-chlorocinnoline
  • Cinnoline, 6-broMo-4-chloro-
  • 6-bromo-4-chlorocinnoline - [B24879]
  • 68211-15-4