Disodium edetate dihydrate
- Product Name
- Disodium edetate dihydrate
- CAS No.
- 6381-92-6
- Chemical Name
- Disodium edetate dihydrate
- Synonyms
- EDTA ACID;EDTA disodium salt dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate;VERSENE;Disodium edetate CRS;EDTA disodium salt 2-hydrate;HAMPENE ACID;EDTA SOLUTION;RED PRIMARY SOLUTION;Disodium Edetate Hydrate
- CBNumber
- CB7153352
- Molecular Formula
- C10H19N2NaO9
- Formula Weight
- 334.26
- MOL File
- 6381-92-6.mol
Disodium edetate dihydrate Property
- Melting point:
- 250 °C (dec.)(lit.)
- Boiling point:
- >100 °C
- Density
- 1.01 g/mL at 25 °C
- refractive index
- n20/D 1.363
- FEMA
- 4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
- Flash point:
- >100℃
- storage temp.
- room temp
- solubility
- 3 M NaOH: 100 mg/mL
- form
- crystalline
- pka
- pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
- color
- ≤5 (0.5 M)(APHA)
- PH
- 4.0-5.5 (25℃, 0.1M in H2O)
- Odor
- Odorless
- PH Range
- 4 - 5 at 10 g/l at 23 °C
- Water Solubility
- soluble
- λmax
- λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025 - BRN
- 3900609
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- QCDUWWPHAVXXQS-UHFFFAOYSA-L
- CAS DataBase Reference
- 6381-92-6(CAS DataBase Reference)
- EPA Substance Registry System
- Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36-52/53-36/38-36/37/38-22
- Safety Statements
- 26-61-37/39-36/37/39-36
- WGK Germany
- 2
- RTECS
- AH4025000
- F
- 3
- TSCA
- Yes
- HS Code
- 29224995
- Toxicity
- LD50 orally in Rabbit: > 2000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H332Harmful if inhaled
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 4010-OP
- Product name
- OmniPur EDTA, Disodium Salt, Dihydrate - CAS 6381-92-6 - Calbiochem
- Packaging
- 250g
- Price
- $91.4
- Updated
- 2024/03/01
- Product number
- 324503
- Product name
- EDTA, Disodium Salt, Dihydrate, Molecular Biology Grade - CAS 6381-92-6 - Calbiochem
- Packaging
- 100g
- Price
- $67.2
- Updated
- 2024/03/01
- Product number
- 27285
- Product name
- Ethylenediaminetetraacetic acid disodium salt dihydrate
- Purity
- meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
- Packaging
- 500g
- Price
- $203
- Updated
- 2024/03/01
- Product number
- 27285
- Product name
- Ethylenediaminetetraacetic acid disodium salt dihydrate
- Purity
- meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
- Packaging
- 1kg
- Price
- $285
- Updated
- 2024/03/01
- Product number
- 27285
- Product name
- Ethylenediaminetetraacetic acid disodium salt dihydrate
- Purity
- meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%
- Packaging
- 6x1kg
- Price
- $1460
- Updated
- 2024/03/01
Disodium edetate dihydrate Chemical Properties,Usage,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Chelating agent; sequestering agent
Uses
Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.
Uses
Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.
Definition
ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.
General Description
Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.
Biochem/physiol Actions
Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.
Purification Methods
Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]
Disodium edetate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Disodium edetate dihydrate manufacturers
- Product
- Disodium edetate dihydrate 6381-92-6
- Price
- US $100.00-75.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000Ton
- Release date
- 2024-08-12
- Product
- Disodium edetate dihydrate 6381-92-6
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-30
- Product
- EDTA-2Na 6381-92-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20MT
- Release date
- 2024-10-30