(+/-)-CGP-12177 HYDROCHLORIDE

Product Name
(+/-)-CGP-12177 HYDROCHLORIDE
CAS No.
81047-99-6
Chemical Name
(+/-)-CGP-12177 HYDROCHLORIDE
Synonyms
Tbhpbo;CGP 12177;CGP12177HCl;S(-)-CGP-12177;TOC CGP 12177;(S)-(-)-CGP-12177;CGP 12177 hydochloride;CGP 12177 HYDROCHLORIDE;(+/-)-CGP-12177 HYDROCHLORIDE;4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
CBNumber
CB7157956
Molecular Formula
C14H21N3O3
Formula Weight
279.33
MOL File
81047-99-6.mol
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(+/-)-CGP-12177 HYDROCHLORIDE Property

Melting point:
>256°C (dec.)
Boiling point:
376.3±37.0 °C(Predicted)
Density 
1.179
storage temp. 
Store at RT
solubility 
DMSO: >10 mg/mL
form 
solid
pka
11.48±0.30(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1134
Product name
CGP12177hydrochloride
Packaging
10
Price
$85
Updated
2021/12/16
Tocris
Product number
1134
Product name
CGP12177hydrochloride
Packaging
50
Price
$282
Updated
2021/12/16
Usbiological
Product number
254930
Product name
CGP 12177 hydrochloride
Packaging
10mg
Price
$310
Updated
2021/12/16
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(+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist.

Definition

ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Biological Activity

Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).

(+/-)-CGP-12177 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-CGP-12177 HYDROCHLORIDE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Hefei fuya biotechnology co. LTD
Tel
18096409024
Email
sales02@foreversyn.com
Country
China
ProdList
1961
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
029-81136151 17392212881
Email
1095@dideu.com
Country
China
ProdList
10001
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58
Guangzhou Tuoshan Biotechnology Co., Ltd.
Tel
19928332050
Country
CHINA
ProdList
161
Advantage
58
Guangzhou Squirrel Biotechnology Co., Ltd.
Tel
17765276361
Country
CHINA
ProdList
109
Advantage
58
Jiangsu Kemix Chemical Co., Ltd.
Tel
--
Fax
--
Email
kemixchem@gmail.com
Country
China
ProdList
743
Advantage
0

81047-99-6, (+/-)-CGP-12177 HYDROCHLORIDERelated Search:


  • (+/-)-CGP-12177 HYDROCHLORIDE
  • CGP 12177 HYDROCHLORIDE
  • 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE
  • CGP12177HCl
  • CGP 12177 hydochloride
  • CGP 12177
  • 4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
  • 4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one
  • (S)-(-)-CGP-12177
  • 1,3-Dihydro-4-[(S)-3-(tert-butylamino)-2-hydroxypropoxy]-2H-benzimidazol-2-one
  • 4-[[(2S)-2-Hydroxy-3-(tert-butylamino)propyl]oxy]-1H-benzimidazole-2(3H)-one
  • S(-)-CGP-12177
  • TOC CGP 12177
  • 2H-Benzimidazol-2-one, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro-
  • Tbhpbo
  • 4-[3-[(tert-butyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one
  • 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one
  • 81047-99-6
  • C14H21N3O3HCl
  • Adrenoceptor