(+/-)-CGP-12177 HYDROCHLORIDE

Product Name
(+/-)-CGP-12177 HYDROCHLORIDE
CAS No.
81047-99-6
Chemical Name
(+/-)-CGP-12177 HYDROCHLORIDE
Synonyms
Tbhpbo;CGP 12177;CGP12177HCl;S(-)-CGP-12177;TOC CGP 12177;(S)-(-)-CGP-12177;CGP 12177 hydochloride;CGP 12177 HYDROCHLORIDE;(+/-)-CGP-12177 HYDROCHLORIDE;(+/-)-CGP-12177 HYDROCHLORIDE
CBNumber
CB7157956
Molecular Formula
C14H21N3O3
Formula Weight
279.33
MOL File
81047-99-6.mol
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(+/-)-CGP-12177 HYDROCHLORIDE Property

Melting point:
>256°C (dec.)
Boiling point:
376.3±37.0 °C(Predicted)
Density 
1.179
storage temp. 
Store at RT
solubility 
DMSO: >10 mg/mL
form 
solid
pka
11.48±0.30(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1134
Product name
CGP12177hydrochloride
Packaging
10
Price
$85
Updated
2021/12/16
Tocris
Product number
1134
Product name
CGP12177hydrochloride
Packaging
50
Price
$282
Updated
2021/12/16
Usbiological
Product number
254930
Product name
CGP 12177 hydrochloride
Packaging
10mg
Price
$310
Updated
2021/12/16
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(+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist.

Definition

ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Biological Activity

Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).

(+/-)-CGP-12177 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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81047-99-6, (+/-)-CGP-12177 HYDROCHLORIDERelated Search:


  • (+/-)-CGP-12177 HYDROCHLORIDE
  • CGP 12177 HYDROCHLORIDE
  • 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE
  • CGP12177HCl
  • CGP 12177 hydochloride
  • CGP 12177
  • 4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
  • 4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one
  • (S)-(-)-CGP-12177
  • 1,3-Dihydro-4-[(S)-3-(tert-butylamino)-2-hydroxypropoxy]-2H-benzimidazol-2-one
  • 4-[[(2S)-2-Hydroxy-3-(tert-butylamino)propyl]oxy]-1H-benzimidazole-2(3H)-one
  • S(-)-CGP-12177
  • TOC CGP 12177
  • 2H-Benzimidazol-2-one, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro-
  • Tbhpbo
  • 4-[3-[(tert-butyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one
  • (+/-)-CGP-12177 HYDROCHLORIDE
  • 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one
  • 81047-99-6
  • C14H21N3O3HCl
  • Adrenoceptor