ChemicalBook > CAS DataBase List > 3'-ADENYLIC ACID

3'-ADENYLIC ACID

Product Name
3'-ADENYLIC ACID
CAS No.
84-21-9
Chemical Name
3'-ADENYLIC ACID
Synonyms
3'-AMP;C01367;A-3'-MP;Ado-3'-P;fromyeast;3'-AMP·H2;ADENYLIC ACID;synadenylicacid;2'and3'-mixture;3'-ADENYLIC ACID
CBNumber
CB7165410
Molecular Formula
C10H14N5O7P
Formula Weight
347.22
MOL File
84-21-9.mol
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3'-ADENYLIC ACID Property

Melting point:
~210 °C (dec.)
Boiling point:
815.5±75.0 °C(Predicted)
Density 
2.32±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
pka
pK1: 3.65(0);pK2: 5.88(-1) (25°C)
form 
Solid
color 
White to Off-White
biological source
yeast
Water Solubility 
0.5g/L(15 ºC)
Merck 
13,158
BRN 
54478
Stability:
Hygroscopic
EPA Substance Registry System
3'-Adenylic acid (84-21-9)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
AU7480320
F 
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A9272
Product name
Adenosine 3′-monophosphate
Purity
from yeast
Packaging
100mg
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
A9272
Product name
Adenosine 3′-monophosphate
Purity
from yeast
Packaging
1g
Price
$654
Updated
2024/03/01
Sigma-Aldrich
Product number
A9272
Product name
Adenosine 3′-monophosphate
Purity
from yeast
Packaging
500mg
Price
$783
Updated
2024/03/01
TRC
Product number
A281840
Product name
Adenosine 3′-monophosphate
Packaging
200mg
Price
$265
Updated
2021/12/16
Biosynth Carbosynth
Product number
NA66252
Product name
Adenosine 3′-monophosphate
Packaging
1g
Price
$400
Updated
2021/12/16
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3'-ADENYLIC ACID Chemical Properties,Usage,Production

Uses

Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

Definition

ChEBI: 3'-AMP is an adenosine 3'-phosphate with a monophosphate group at the 3'-position. It has a role as a mouse metabolite, a human metabolite and an Escherichia coli metabolite. It is an adenosine 3'-phosphate and a purine ribonucleoside 3'-monophosphate. It is a conjugate acid of a 3'-AMP(2-).

Purification Methods

It crystallises from large volumes of H2O in needles as the monohydrate, but is not very soluble in boiling H2O. Under acidic conditions it forms an equilibrium mixture of 2' and 3' adenylic acids via the 2',3'-cyclic phosphate. When heated with 20% HCl, it gives a quantitative yield of furfural after 3hours, unlike 5'-adenylic acid which only gives traces of furfural. The yellow monoacridine salt has m 175o(dec), and the diacridine salt has m 177o (225o)(dec). [Brown & Todd J Chem Soc 44 1952, Takaku et al. Chem Pharm Bull Jpn 21 1844 1973, NMR: Ts'O et al. Biochemistry 8 997 1969, Beilstein 26 III/IV 3607.]

3'-ADENYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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84-21-9, 3'-ADENYLIC ACIDRelated Search:

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE c-di-AMP ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT INDEX NAME NOT YET ASSIGNED [5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxyphosphonic acid 2'-O-Methyladenosine ADP [(2R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-oxolan-2-yl]me thoxyphosphonic acid 2'-Deoxyadenosine P1,P2-di(adenosine-5')pyrophosphate sodium salt 2-amino-2-deoxy-beta-arabinofuranosyladenine 2'-Deoxyadenosine-5'-triphosphate, trisodiuM salt 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 2'-Adenylic acid, 3',5'-bis(dihydrogen phosphate) (9CI) Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[1-(dimethylamino)ethylidene]- (9CI) Acetyl coenzyme A sodium salt ATP disodium salt FLAVIN ADENINE DINUCLEOTIDE

  • synadenylicacid
  • ADENYLIC ACID, YEAST
  • ADENYLIC ACID
  • ADENYLIC ACID, B
  • ADENOSINE 3'-MONOPHOSPHATE
  • ADENOSINE 3'-PHOSPHATE
  • ADENOSINE 3'-PHOSPHORIC ACID
  • ADENOSINE-3'-MONOPHOSPHORIC ACID
  • 3'-ADENYLIC ACID
  • 3'-AMP
  • adenosine 3'-phosphate monohydrate
  • A-3'-MP
  • Adenosine 3'-monophosphate;3'-Adenylic acid;A-3'-MP;3'-AMP;yeast adenylic acid;Adenosine 3'-monophosphoric acid;Adenosine-3'-phosphoric acid;Adenylic acid b;
  • yeast adenylic acid
  • ADENYLIC ACID (2-'' AND 3''- MIXTURE): FROM YEAST
  • ADENOSINE 3'-MONOPHOSPHATE FREE ACID
  • 2'and3'-mixture
  • 3'-AMP=3'-Adenylicacid
  • fromyeast
  • ADENYLIC ACID (2-' AND 3'- MIXTURE)
  • [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyphosphonic acid
  • 3μ-Adenylic acid, 3μ-AMP
  • Ado-3'-P
  • Adenosine 3'-monophosphate,from Yeast
  • 3'-Adenosine monophosphate
  • Amp 3'-phosphate
  • C01367
  • ADENOSINE-3'-MONOPHOSPHATE(SH)
  • 3'-AMP·H2
  • adenosine 3J-phosphate monohydrate
  • Adensosine-3'-Monophosphate (AS)
  • 3'Adenylic acid,3' Adenylic acid
  • Cyclic adenosine monophosphate Impurity 2
  • Adenosine Impurity 40
  • (2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate
  • (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
  • Adenosine-3'-monophosphate
  • 3'-ADENYLIC ACID
  • Adenosine Impurity N9
  • 3''-Adenylic acid
  • 3''-Adenylic acid, 10 mM in DMSO
  • 84-21-9
  • Biochemicals and Reagents
  • BioChemical
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleotides
  • Pharmaceutical Intermediates
  • Nucleotides and Nucleic Acids
  • Nucleic acids