Flavin adenine dinucleotide

Product Name: Flavin adenine dinucleotide
CAS No.: 146-14-5
Chemical Name: Flavin adenine dinucleotide
Synonyms: DISODIUM FLAVINE ADENINE DINUCLEOTIDE;Fademin;flavitan;flavinat;Flavinin;Wakadenin;NSC 112207;FAD Powder;Flavine Adenine;5'-ester with adenosine
CBNumber: CB0294159
Molecular Formula: C27H33N9O15P2
Formula Weight: 785.55
MOL File: 146-14-5.mol

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Flavin adenine dinucleotide Property

Density: 2.08±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Methanol (Slightly, Heated), Water (Slightly)
pka: 1.13±0.50(Predicted)
form: powder
color: orange
Merck: 4091
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: VWWQXMAJTJZDQX-ZGGJIJKNNA-N
CAS DataBase Reference: 146-14-5
EPA Substance Registry System: Riboflavin 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with adenosine (146-14-5)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: AU7470000
F: 8-10-21
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

TRC

Product number: F532268
Product name: FlavineAdenineDinucleotide
Packaging: 25mg
Price: $1200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0003041
Product name: FLAVIN ADENINE DINUCLEOTIDE
Purity: 98.00%
Packaging: 25MG
Price: $408.85
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0003041
Product name: FLAVIN ADENINE DINUCLEOTIDE
Purity: 98.00%
Packaging: 100MG
Price: $435.4
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0003041
Product name: FLAVIN ADENINE DINUCLEOTIDE
Purity: 98.00%
Packaging: 250MG
Price: $488.5
Updated: 2021/12/16

Crysdot

Product number: CD70002093
Product name: Flavine-adeninedinucleotide
Purity: 97%
Packaging: 5g
Price: $357
Updated: 2021/12/16

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Flavin adenine dinucleotide Chemical Properties,Usage,Production

Description

Flavin adenine dinucleotide (FAD) is a cofactor for cytochrome-b5 reductase, the enzyme that maintains hemoglobin in its functional reduced state, and for glutathione reductase. This enzyme also protects erythrocytes from oxidative damage. FAD is a redox cofactor of several essential reactions in metabolism. This cofactor exists in two redox states, with FAD and FADH2 being the oxidized and reduced forms, respectively. FAD is formed of a riboflavin moiety (vitamin B2) coupled to a phosphate group of an ADP molecule. The reaction starts with the conversion of riboflavin into flavin mononucleotide catalyzed by riboflavin kinase. Flavin mononucleotide is subsequently transformed into FAD by adding an AMP moiety from ATP catalyzed by FAD-synthase. Therefore, FAD availability is tightly dependent on vitamin B2 and energy metabolism[1].

References

[1] Schnekenburger, M. and M. Diederich. “Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches.”Epigenetic Cancer Therapy (2015): 393-425.

Chemical Properties

solid

Uses

Labelled Flavine Adenine xidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase

Uses

The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.

Definition

An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5′-position.

Purification Methods

Small quantities of FAD are purified by paper chromatography using tert-butyl alcohol/water, cutting out the main spot and eluting with water. Larger amounts can be precipitated from water as the uranyl complex by adding a slight excess of uranyl acetate to a solution at pH 6.0, dropwise and with gentle stirring. The solution is set aside overnight in the cold, and the precipitate is centrifuged off, washed with small portions of cold EtOH, then with cold peroxide-free diethyl ether. It is dried in the dark under vacuum over P2O5 at 50-60o. The uranyl complex is suspended in water, and, after adding sufficient 0.01M NaOH to adjust the pH to 7, the precipitate of uranyl hydroxide is removed by centrifugation [Huennekens & Felton Methods Enzymol 3 954 1957]. It can also be crystallised from water. It should be kept in the dark. More recently it was purified by elution from a DEAE-cellulose (Whatman DE 23) column with 0.1M phosphate buffer pH 7, and the purity was checked by TLC. [Holt & Cotton, J Am Chem Soc 109 1841 1987, Beilstein 26 III/IV 3632.]

Flavin adenine dinucleotide Preparation Products And Raw materials

Raw materials

Preparation Products

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Flavin adenine dinucleotide Suppliers

Canada 1 China 106 Europe 1 Germany 5 India 4 United Kingdom 6 United States 16 Global 139

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View Lastest Price from Flavin adenine dinucleotide manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: FLAVIN ADENINE DINUCLEOTIDE 146-14-5
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2021-07-28

Henan Aochuang Chemical Co.,Ltd.

Product: FLAVIN ADENINE DINUCLEOTIDE 146-14-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: FLAVIN ADENINE DINUCLEOTIDE 146-14-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 100KG
Release date: 2021-09-24

146-14-5, Flavin adenine dinucleotideRelated Search:

Stannous chloride dihydrate Sulfoxaflor Nuclease Coenzyme A NAD+ Glutathione Nicotinamide Adenine Flavin adenine dinucleotide disodium salt FLAVIN ADENINE DINUCLEOTIDE N(6)-aminohexyl-flavin adenine dinucleotide FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT N-HYDRATE,FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT DIHYDRATE,FLAVIN ADENINE DINUCLEOTIDE NA-SALT FLAVIN ADENINE DINUCLEOTIDE DISODIUM SALT HYDRATE Flavin adenine dinucleotide ammonium salt 500 MG FLAVIN ADENINE DINUCLEOTIDE.NA-SALT PURE flavin-adenine dinucleotide phosphate FLAVIN ADENINE DINUCLEOTIDE-AGAROSE Flavin Adenine Dinucleotide, Disodium Salt (1.24544)

adenine-flavindinucleotide

adenine-flavinedinucleotide

adenine-riboflavindinuceotide

flavitan

isoalloxazine-adeninedinucleotide

riboflavin5’-(trihydrogendiphosphate),5’.fwdarw.5’-esterwithadenosine

riboflavin5’-(trihydrogendiphosphate),5’-5’-esterwithadenosine

riboflavin-adeninedinucleotide

riboflavine-adeninedinucleotide

FLAVIN ADENINE DINUCLEOTIDE

Flavine-adenine dinucleotide

DISODIUM FLAVINE ADENINE DINUCLEOTIDE

adenine-riboflavindinucleotide

adenosine5’-(trihydrogenpyrophosphate),5’-5’-esterwithriboflavine

flavinadenindinucleotide

flavinadeninedinucleotidedisodium

flavinat

flavineadeninedinucleotide,disodiumflavineadeninedinucleotide

flavineadenosinediphosphate

FLAVIN ADENINE DINUCLEOTIDE 2NA (FAD)

Riboflavine 5'-adenosine diphosphate

Adenine-riboflavine dinucleotide

Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with riboflavine (8CI)

Fademin

NSC 112207

Riboflavin 5'-adenosine diphosphate

Riboflavine, 5'-ester with adenosine 5'-diphosphate (8CI)

FLAVINE ADENINE DINUCLEOTIDE SODIUM SALT extrapure

flavin adenosine dinucleotide

Riboflavin 5-(trihydrogen diphosphate), P?5-ester with adenosine

Riboflavin 5'-(trihydrogen diphosphate)

5'-ester with adenosine

Riboflavin5'-(trihydrogen diphosphate), P'&reg

Flavinin

Wakadenin

Flavine-adenine dinucleotide,96%

Flavine Adenine

Flavin adenine dinucleotide ,95%

FLAVIN ADENINE DINUCLEOTIDE USP/EP/BP

flavine Adenine Dinucleotide-13C5 Ammonium SaltQ: What is flavine Adenine Dinucleotide-13C5 Ammonium Salt Q: What is the CAS Number of flavine Adenine Dinucleotide-13C5 Ammonium Salt

Flavine Adenine Dinucleotide Sodium Salt (FAD) extrapure, 95%

FAD Powder

(((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(((((2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl)oxy)(hydroxy)phosphoryl)oxy)phosphinic acid

Flavine adenine dinucleotide,FAD

Riboflavin5'-(trihydrogen diphosphate), P'?5'-ester with adenosine

146-14-5

C2213C5H31N9Na2O15P2

C27H31N9O15P2Na2

C27H33N9O15P2

C27N33N9O15P2

Metabolic Pathways

Metabolomics

Electron Transport and Cellular Respiration

Cofactors and Substrates

BioChemical

Biochemistry

Vitamin Derivatives

Vitamins