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Dodecyltriphenylphosphonium bromide

Application
Product Name
Dodecyltriphenylphosphonium bromide
CAS No.
15510-55-1
Chemical Name
Dodecyltriphenylphosphonium bromide
Synonyms
Dodecyl-TPP;dodecyltriphenylphosphonium;Triphenyldodecylphosphonium;Triphenyl(dodecyl)phosphonium;Dodecyltriphenylphosphine bromide;DodecyltriphenylphosphoniuM broMid;Lauryltriphenylphosphonium bromide;DODECYLTRIPHENYLPHOSPHONIUM BROMIDE;Triphenyldodecylphosphonium·bromide;PHOSPHONIUM,DODECYLTRIPHENYL-,BROMIDE
CBNumber
CB7166437
Molecular Formula
C30H40BrP
Formula Weight
511.52
MOL File
15510-55-1.mol
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Dodecyltriphenylphosphonium bromide Property

Melting point:
85-88 °C(lit.)
storage temp. 
RT
solubility 
Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL)
form 
solid
color 
White
Sensitive 
Hygroscopic
BRN 
3581921
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Cosmetics Ingredients Functions
ANTIMICROBIAL
CAS DataBase Reference
15510-55-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
099906
Product name
Dodecyltriphenylphosphonium bromide
Purity
95+%
Packaging
10g
Price
$80
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ING0004215
Product name
DODECYL(TRIPHENYL)PHOSPHONIUM BROMIDE
Purity
95.00%
Packaging
10G
Price
$162.75
Updated
2021/12/16
Matrix Scientific
Product number
099906
Product name
Dodecyltriphenylphosphonium bromide
Purity
95+%
Packaging
1g
Price
$19
Updated
2021/12/16
Matrix Scientific
Product number
099906
Product name
Dodecyltriphenylphosphonium bromide
Purity
95+%
Packaging
5g
Price
$51
Updated
2021/12/16
Ambeed
Product number
A888771
Product name
Dodecyltriphenylphosphonium bromide
Purity
98+%
Packaging
25g
Price
$59
Updated
2021/12/16
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Dodecyltriphenylphosphonium bromide Chemical Properties,Usage,Production

Application

Dodecyltriphenylphosphine bromide is a quaternary phosphine salt, which has a wide range of applications as a Wittig reagent, phase transfer catalyst, and surfactant. Quaternary phosphine salts are also a new generation of highly efficient, broad-spectrum, and low-toxicity bactericides, possessing not only strong bactericidal ability but also low foaming, strong slime-removing ability, and a wide applicable pH range. Dodecyltriphenylphosphine bromide exhibits good bactericidal effects against sulfate-reducing bacteria, but its bactericidal effect against heterotrophic bacteria is relatively poor. Dodecyltriphenylphosphine bromide can be prepared by reacting triphenylphosphine with 1-bromododecane.

Description

Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2

Definition

ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions.

Synthesis

26.2 g of triphenylphosphine, 24.9 g of 1-bromododecane and 30 ml of N,N-dimethylformamide were added to a three-necked flask equipped with a reflux condenser tube and heated to reflux under the protection of nitrogen, and the reaction was carried out. After 36h, the reaction was cooled and the solvent was evaporated under reduced pressure. The product was dissolved in 100 ml of water, extracted three times with 80 ml of n-hexane and dried in a vacuum drying oven to give a light yellow waxy solid, which was dissolved in . The solid was dissolved in 30 ml of ethyl acetate, precipitated with ether and filtered, 28.6 g of white waxy solid was obtained, the yield was 61.4%.

References

[1] nan

Dodecyltriphenylphosphonium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Dodecyltriphenylphosphonium bromide Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6912
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Sci General Material & Chemical Ltd
Tel
021-58388037;21-58388037 13472507714
Email
35177634@qq.com;1589045147@qq.com
Country
China
ProdList
805
Advantage
55
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View Lastest Price from Dodecyltriphenylphosphonium bromide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Dodecyltriphenylphosphonium bromide 15510-55-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23
Henan Aochuang Chemical Co.,Ltd.
Product
Dodecyltriphenylphosphonium bromide 15510-55-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10
Shaanxi Dideu Medichem Co. Ltd
Product
DodecyltriphenylphosphoniuM bromide 15510-55-1
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-01-17

15510-55-1, Dodecyltriphenylphosphonium bromideRelated Search:


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