Pseudohypericin
- Product Name
- Pseudohypericin
- CAS No.
- 55954-61-5
- Chemical Name
- Pseudohypericin
- Synonyms
- PSEUDOHYPERICIN;Pseudohypericine;Pseudohypericin-RM;Pseudohypericin USP/EP/BP;PSEUDOPELLETIERINE HYDROCHLORIDE(RG);1,3,4,6,8,13-Hexahydroxy-10-hydroxymethyl-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione;1,3,4,6,8,13-Hexahydroxy-10-(hydroxymethyl)-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione;Phenanthro[1,10,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-;Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-, stereoisomer
- CBNumber
- CB7177725
- Molecular Formula
- C30H16O9
- Formula Weight
- 520.44
- MOL File
- 55954-61-5.mol
Pseudohypericin Property
- Boiling point:
- 1089.1±65.0 °C(Predicted)
- Density
- 1.994±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- powder
- pka
- 7.16±0.20(Predicted)
- color
- brown
- InChIKey
- YXBUQQDFTYOHQI-UHFFFAOYSA-N
- SMILES
- Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c56)c78
- CAS DataBase Reference
- 55954-61-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 22-36
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 Oral
- Hazardous Substances Data
- 55954-61-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHL89261
- Product name
- Pseudohypericin
- Purity
- phyproof? Reference Substance
- Packaging
- 5MG
- Price
- $459
- Updated
- 2025/07/31
- Product number
- 51593
- Product name
- Pseudohypericin
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $702
- Updated
- 2022/05/15
- Product number
- P839563
- Product name
- Pseudohypericin
- Packaging
- 0.5mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FP65509
- Product name
- Pseudohypericin
- Packaging
- 2mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- PXT0000174
- Product name
- PSEUDOHYPERICIN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $261.45
- Updated
- 2021/12/16
Pseudohypericin Chemical Properties,Usage,Production
Uses
Pseudohypericin is a specific inhibitor of protein kinase C and D-β-Hydroxylase. Also, it is used in determination of potential drug candidate molecules of Hypericum perforatum for COVID-19 treatment.
Definition
ChEBI: Pseudohypericin is an ortho- and peri-fused polycyclic arene.
Biological Activity
One of the major bioactive constituents of St. Johnμs wort (Hypericum perforatum). Implicated in the antidepressant efficacy of St. Johnμs wort.
Synthesis
Pseudohypericin will be extracted by the means of water immersion means pre-treatment of Hypericum perforatum raw materials, by alcohol extraction to extract solvent containing hypericin and pseudohypericin and other active ingredients, through the heating and steaming concentration of the extract solvent, to get rich in active ingredients of the extract, can be used for direct drying of the preparation of extract extracts of the extract powder, and can also be further separated, the preparation of high purity of the hypericin and pseudohypericin. Specifically: the method of extracting and preparing a dry powder of the extract in accordance with internationally accepted standards from the raw material of Hypericum perforatum, characterized in that: the raw material of Hypericum perforatum is crushed, pretreated by soaking in water, and then the pretreated raw material is extracted with an alcoholic solution in order to obtain an alcoholic solution containing hypericin and pseudohypericin, and the extracted alcoholic solution is separated, and then the extraction solvent is concentrated, dried, and extracted soaking paste powder is prepared , or used for further refinement to prepare high content active ingredient extracts.
Enzyme inhibitor
This anti-retroviral agent (FW = 520.45 g/mol) inhibits protein kinase C with an IC50 value of 28.7 μM and dopamine b-hydroxylase with IC50 = 3 μM. Pseudohypericin is a component of St. John’s Wort (Hypericum perforatum). Target(s): dopamine b-hydroxylase; inositoltrisphosphate 3-kinase; and protein kinase C.
Pseudohypericin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pseudohypericin manufacturers
- Product
- Pseudohypericin 55954-61-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-16
- Product
- Pseudohypericin 55954-61-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-12