4-Fluorocinnamic acid
- Product Name
- 4-Fluorocinnamic acid
- CAS No.
- 459-32-5
- Chemical Name
- 4-Fluorocinnamic acid
- Synonyms
- AKOS 92741;(E)-3-(4-FL;AKOS BB/0035;4-fluoride acid;AKOS BBS-00006474;4-Fluorocinmic acid;TIMTEC-BB SBB005718;RARECHEM BK HC T330;4-FUOROCINNAMIC ACID;OTAVA-BB BB0103940052
- CBNumber
- CB7178186
- Molecular Formula
- C9H7FO2
- Formula Weight
- 166.15
- MOL File
- 459-32-5.mol
4-Fluorocinnamic acid Property
- Melting point:
- 209-210 °C (lit.)
- Boiling point:
- 290°C (rough estimate)
- Density
- 1.2247 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.43±0.10(Predicted)
- form
- Crystalline Solid
- color
- White to off-white
- BRN
- 2613441
- InChI
- InChI=1S/C9H7FO2/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6H,(H,11,12)
- InChIKey
- ISMMYAZSUSYVQG-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C=CC1=CC=C(F)C=C1
- CAS DataBase Reference
- 459-32-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Fluorocinnamic acid(459-32-5)
Safety
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34
- Safety Statements
- 37/39-26-45-36/37/39-27-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 222720
- Product name
- 4-Fluorocinnamic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $48.45
- Updated
- 2025/07/31
- Product number
- F0244
- Product name
- 4-Fluorocinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- F0244
- Product name
- 4-Fluorocinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $90
- Updated
- 2025/07/31
- Product number
- F588620
- Product name
- 4-Fluorocinnamic Acid
- Packaging
- 25g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 2921-3-04
- Product name
- 4-Fluorocinnamic acid
- Purity
- 99%
- Packaging
- 250g
- Price
- $95
- Updated
- 2021/12/16
4-Fluorocinnamic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Fluorocinnamic acid was used in growth medium for the Arthrobacter sp. strain G1.
Definition
ChEBI: 4-Fluorocinnamic acid is a member of cinnamic acids.
General Description
The shock loading of 4-fluorocinnamic acid (4-FCA) was treated using a rotating biological contactor (RBC).
Synthesis
352-34-1
79-10-7
459-32-5
GENERAL METHODS: Lithium tert-butanol or potassium tert-butanol (3.0 mmol), water (2.0 mL), and acrylic acid (1.2 mmol) were sequentially added to a Schlenk reaction tube under nitrogen atmosphere and stirred for 10 min at room temperature. Subsequently, p-fluoroiodobenzene (1.0 mmol) and palladium(II)-imidazole complex 1 (1.0 mol%) were added. The reaction mixture was stirred at 100 °C for 12 hours. After completion of the reaction, it was cooled to room temperature, acidified to pH 1 with 4 M hydrochloric acid and subsequently extracted with ethyl acetate. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by rapid chromatography on a silica gel column to give pure p-fluorocinnamic acid.
References
[1] Journal of Chemical Research, 2013, vol. 37, # 5, p. 294 - 297
[2] Synlett, 2006, # 18, p. 2959 - 2964
[3] Journal of Organic Chemistry, 2004, vol. 69, # 23, p. 8105 - 8107
[4] Reactive and Functional Polymers, 2011, vol. 71, # 7, p. 756 - 765
4-Fluorocinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Fluorocinnamic acid manufacturers
- Product
- 4-Fluorocinnamic acid 459-32-5
- Price
- US $25.00/ASSAYS
- Min. Order
- 100ASSAYS
- Purity
- 99.5%
- Supply Ability
- 100 mt
- Release date
- 2024-11-18
- Product
- 4-Fluorocinnamic acid 459-32-5
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-16
- Product
- 4-Fluorocinnamic acid 459-32-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28