5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
- Product Name
- 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
- CAS No.
- 1036027-54-9
- Chemical Name
- 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
- Synonyms
- 5-(TrifluoroMethyl)-7-azaindole;5-TRIFLUOROMETHYL-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)-;1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 5-(TrifluoroMethyl)-7-azaindole
- CBNumber
- CB71871817
- Molecular Formula
- C8H5F3N2
- Formula Weight
- 186.13
- MOL File
- 1036027-54-9.mol
5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Property
- Melting point:
- 104-105 °C
- Density
- 1.447±0.06 g/cm3(Predicted)
- pka
- 12.82±0.40(Predicted)
- form
- solid
- color
- Off-white to light brown
Safety
- RIDADR
- 2811
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
N-Bromosuccinimide Price
- Product number
- ADE000933
- Product name
- 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $792
- Updated
- 2024/03/01
- Product number
- T791743
- Product name
- 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- PC200224
- Product name
- 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 250mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- 035768
- Product name
- 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 100mg
- Price
- $237
- Updated
- 2021/12/16
- Product number
- HCH0036085
- Product name
- 5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $864.17
- Updated
- 2021/12/16
5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Usage,Production
Synthesis
A solution of 3.4 g of 5-trifluoromethyl-3-[(trimethylsilyl)ethynyl]pyridin-2-amine and 2.96 g of potassium tert-butylate in 55 cm3 of N-methylpyrrolidinone is heated at 90 ℃. for three hours. The mixture is cooled to room temperature and then poured slowly into 250 cm3 of water saturated with ammonium chloride. The mixture is diluted with ethyl acetate and filtered, separating the phases into their isomers. The aqueous phase is extracted with ethyl acetate (2*100 cm3). The organic phases are combined, dried over magnesium sulphate and concentrated under a vacuum. The residue is slowly removed in water, and the resultant suspension is filtered. The solid is dried under vacuum to obtain 1.58 g of 5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine as a brown powder.
5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine manufacturers
- Product
- 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 1036027-54-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 1036027-54-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 1036027-54-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-12-18