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Cyclohexanone, 4-(4-chlorophenyl)-

Product Name
Cyclohexanone, 4-(4-chlorophenyl)-
CAS No.
14472-80-1
Chemical Name
Cyclohexanone, 4-(4-chlorophenyl)-
Synonyms
4-(4-chlorophenyl)-;4-(p-Chlorophenyl)cyclohexanone;4-(4-chlorophenyl)cyclohexanone;4-(4-chlorophenyl)cyclohexan-1-one;4-(4-chlorophenyl)-1-cyclohexanone;Cyclohexanone, 4-(4-chlorophenyl)-
CBNumber
CB71872223
Molecular Formula
C12H13ClO
Formula Weight
208.68
MOL File
14472-80-1.mol
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Cyclohexanone, 4-(4-chlorophenyl)- Property

Melting point:
138-141 °C
Boiling point:
138-141 °C(Press: 0.5 Torr)
Density 
1.165±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform, Dichloromethane
form 
Solid
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C377800
Product name
4-(4-Chlorophenyl)cyclohexanone
Packaging
50mg
Price
$95
Updated
2021/12/16
TRC
Product number
C377800
Product name
4-(4-Chlorophenyl)cyclohexanone
Packaging
1g
Price
$605
Updated
2021/12/16
AK Scientific
Product number
4277CV
Product name
4-(4-Chlorophenyl)cyclohexanone
Packaging
5g
Price
$508
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20341
Product name
4-(4-Chlorophenyl)cyclohexanone
Packaging
500mg
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20341
Product name
4-(4-Chlorophenyl)cyclohexanone
Packaging
1g
Price
$200
Updated
2021/12/16
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Cyclohexanone, 4-(4-chlorophenyl)- Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

4-(4-Chlorophenyl)cyclohexanone (cas# 14472-80-1) is a compound useful in organic synthesis.

Synthesis

1409956-58-6

14472-80-1

1409956-62-2

529-34-0

The general procedure for the synthesis of 4-(4-chlorophenyl)cyclohexanone, compound (CAS:1409956-62-2) and 1-tetrahydronaphthalenone from compound (CAS:1409956-58-6) was as follows: 2-(4-(4-chlorophenyl)-1-hydroxycyclohexyl)-3,4-dihydronaphthalen-1-(2H)-one (12.0 g, 0.034 mol) was added to a reactor equipped with an overhead stirrer and reflux condenser with a heating jacket. Toluene (200 mL) was added to suspend the feedstock, followed by the addition of p-toluenesulfonic acid (0.3 g, 2.5 mol%) to the reaction mixture. The reaction mixture was heated to 60°C and stirred for 6 h. The reaction progress was monitored by thin layer chromatography (TLC). After completion of the reaction, the reaction mixture was cooled to room temperature and the solvent was evaporated under reduced pressure to give a residue. Ethyl acetate (150 mL) was added to the residue and washed with saturated aqueous sodium bicarbonate (NaHCO3). After separation of the organic layer, the solvent was evaporated to give the crude product. The crude product was purified by recrystallization from methanol to give a white solid compound (5.3 g, 50% yield). Gas chromatographic (GC) analysis of the mother liquor obtained after recrystallization showed that α-tetralone and 4-(4-chlorophenyl)cyclohexanone were present in an approximately 1:1 ratio (based on the corresponding retention times and area percentage profiles in the mother liquor) in 50% total yield. gC retention time: α-tetralone (XII): 17.21 min (area percentage: 46).

References

[1] Patent: WO2013/14486, 2013, A1. Location in patent: Page/Page column 19

Cyclohexanone, 4-(4-chlorophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclohexanone, 4-(4-chlorophenyl)- Suppliers

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View Lastest Price from Cyclohexanone, 4-(4-chlorophenyl)- manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Cyclohexanone, 4-(4-chlorophenyl)- 14472-80-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Cyclohexanone, 4-(4-chlorophenyl)- 14472-80-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09