1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

Product Name: 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
CAS No.: 85375-15-1
Chemical Name: 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Synonyms: skf-89976a;SKF89976AHCl;SKF 89976A HYDROCHLORIDE;l-SKF89976A hydrochloride;d,l-SKF89976A hydrochloride;1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride;1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride;Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
CBNumber: CB7194179
Molecular Formula: C22H26ClNO2
Formula Weight: 371.9
MOL File: 85375-15-1.mol

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1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Property

storage temp.: Inert atmosphere,2-8°C
solubility: DMSO: 20 mg/mL, soluble
form: solid
color: white

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Safety

WGK Germany: 3
RTECS: TM6241000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S9066
Product name: SKF-89976A
Purity: >98% (HPLC), solid
Packaging: 10mg
Price: $143
Updated: 2022/05/15

Tocris

Product number: 1081
Product name: SKF89976Ahydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $159
Updated: 2021/12/16

Tocris

Product number: 1081
Product name: SKF89976Ahydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $658
Updated: 2021/12/16

TRC

Product number: S550003
Product name: SKF-89976A
Packaging: 25mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-6040
Product name: SKF89976Ahydrochloride
Purity: 99.33%
Packaging: 50mg
Price: $420
Updated: 2021/12/16

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1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SKF-89976A is a GABA transporters (GATs) type 1 inhibitor.

Biological Activity

A potent GABA uptake inhibitor, selective for GAT-1 (IC 50 values are 0.13, 550, 944 and 7210 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (K i = 7 μ M) and transmitter-gated current non-competitively (K i = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo .

storage

+4°C (desiccate)

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Suppliers

China 63 Germany 2 Switzerland 1 United Kingdom 3 United States 13 Global 82

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85375-15-1, 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDERelated Search:

3-Methyl-1-butene 1-METHYLPIPERIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

SKF 89976A HYDROCHLORIDE

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

SKF89976AHCl

skf-89976a

1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride

1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride

l-SKF89976A hydrochloride

d,l-SKF89976A hydrochloride

Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride

85375-15-1

C22H25NO2HCl

Ion Channels

Ligand-Gated Ion Channels

GABA and Glycine Receptor Modulators

Cell Biology

Cell Signaling and Neuroscience

BioChemical

GABA/Glycine receptor

GABA