2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide

Product Name: 2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
CAS No.: 667880-11-7
Chemical Name: 2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
Synonyms: ZINC00640089;Benz[cd]indole-1(2H)-acetamide, 2-oxo-N-[2-(trifluoromethyl)phenyl]-;2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide;2-{3-oxo-2-azatricyclo[6.3.1.0?,12]dodeca-1(11),4(12),5,7,9-pentaen-2-yl}-N-[2-(trifluoromethyl)phenyl]acetamide
CBNumber: CB71967855
Molecular Formula: C20H13F3N2O2
Formula Weight: 370.32
MOL File: 667880-11-7.mol

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2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide Property

Boiling point:: 589.6±50.0 °C(Predicted)
Density: 1.455±0.06 g/cm3(Predicted)
form: Solid
pka: 12.82±0.70(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide Chemical Properties,Usage,Production

Uses

ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC)[1].

References

[1] Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22(16):8581. DOI:10.3390/ijms22168581

2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide Suppliers

China 18 The Netherlands 1 United States 1 Global 20

Shanghai YuanYe Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Jingmo (Xiamen) Biotechnology Co., Ltd

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Bide Pharmatech Ltd.

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TargetMol Chemicals Inc.

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Henan Alpha Chemical Co., Ltd.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Anqing YanZhi Pharma Discovery Co.,Ltd.

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667880-11-7, 2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamideRelated Search:

4-(2,3-dihydro-1,4-benzodioxin-6-ylcarbonyl)-3-hydroxy-5-[4-(pentyloxy)phenyl]-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one ZINC03129319 (R)-ZINC-3573 ((R)-ZINC3573) 1-Pyrrolidinecarboxamide, 2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]- 1-(4,6-dimethylpyrimidin-2-yl)-3-[2-(trifluoromethyl)phenyl]guanidine 3,4-dihydro-1H-isoquinolin-2-yl-[3-(1H-indol-4-yl)-1,2,4-oxadiazol-5-yl]methanone 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N-(tetrahydro-2H-pyran-4-yl)- ZINC13466751 6-(3,4-dimethoxyphenyl)-3-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 6-(3,4-dimethoxyphenyl)-3-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 4(1H)-Quinazolinone, 2,3-dihydro-3-(2-thiazolylmethyl)-2-thioxo- FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH ZINC36617540 N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide 1-(2-(4-(4-(4-chlorophenyl)-5-methyl-1H-pyrazol-3-yl)-3-hydroxyphenoxy)ethyl)piperidine-4-carboxamide 1-(2-(3-hydroxy-4-(4-phenyl-1H-pyrazol-3-yl)phenoxy)ethyl)piperidine-4-carboxamide 2H-1-Benzopyran-2-one, 3-[2-[(3-acetylphenyl)amino]-4-thiazolyl]-

2-(2-oxobenzo[cd]indol-1(2H)-yl)-N-[2-(trifluoromethyl)phenyl]acetamide

ZINC00640089

Benz[cd]indole-1(2H)-acetamide, 2-oxo-N-[2-(trifluoromethyl)phenyl]-

2-{3-oxo-2-azatricyclo[6.3.1.0?,12]dodeca-1(11),4(12),5,7,9-pentaen-2-yl}-N-[2-(trifluoromethyl)phenyl]acetamide

667880-11-7

C20H13F3N2O2