Homovanillic acid

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Homovanillic acid

Product Name: Homovanillic acid
CAS No.: 306-08-1
Chemical Name: Homovanillic acid
Synonyms: HVA;Homovanilic acid;4-HYDROXY-3-METHOXYPHENYLACETIC ACID;4-Hydroxy-3-methoxybenzeneacetic acid;Benzeneacetic acid, 4-hydroxy-3-methoxy-;JACS-306-08-1;homovanillicaci;Vanilacetic acid;HOMOVANIUIC ACID;Vanillacetic Acid
CBNumber: CB7198081
Molecular Formula: C9H10O4
Formula Weight: 182.17
MOL File: 306-08-1.mol

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Homovanillic acid Property

Melting point:: 142-145 °C(lit.)
Boiling point:: 235.56°C (rough estimate)
Density: 1.1634 (rough estimate)
refractive index: 1.4209 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 4.39±0.10(Predicted)
form: Crystalline Powder
color: White to beige
Water Solubility: soluble
Merck: 14,4740
BRN: 2213447
Stability:: Hygroscopic
LogP: 0.330
CAS DataBase Reference: 306-08-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzeneacetic acid, 4-hydroxy-3-methoxy-(306-08-1)
EPA Substance Registry System: Homovanillic acid (306-08-1)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 10-23
TSCA: T
HazardClass: IRRITANT
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H1252
Product name: Homovanillic acid
Purity: Fluorimetric reagent
Packaging: 1g
Price: $92.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 69673
Product name: Homovanillic acid
Purity: analytical standard
Packaging: 25mg
Price: $71.4
Updated: 2024/03/01

TCI Chemical

Product number: H0339
Product name: 4-Hydroxy-3-methoxyphenylacetic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $42
Updated: 2024/03/01

TCI Chemical

Product number: H0339
Product name: 4-Hydroxy-3-methoxyphenylacetic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $141
Updated: 2024/03/01

Alfa Aesar

Product number: A12441
Product name: Homovanillic acid, 98+%
Packaging: 1g
Price: $72.4
Updated: 2024/03/01

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Homovanillic acid Chemical Properties,Usage,Production

Description

Homovanillic acid (HVA) is a dopamine metabolite. It is formed via deamination of dopamine by monoamine oxidase (MAO) to produce 3,4-dihydroxyphenylacetic acid (DOPAC; ) followed by DOPAC metabolism by catechol-O-methyltransferase (COMT). HVA undergoes hydrogen peroxide-dependent oxidation in the presence of horseradish peroxidase to form a fluorescent dimer that displays excitation/emission maxima of 312/420 nm, respectively. It has been used to quantify hydrogen peroxide production in macrophages and neutrophils.

Chemical Properties

white to beige crystalline powder

Uses

Fluorimetric reagent and major catecholamine metaboliteHomovanillic acid is used as a reagent in the determination of oxidative enzymes. It is associated with dopamine levels in the brain. Its presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.

Uses

A neuroendocrine tumor marker. Dihydroxyphenylacetic Acid (DOPAC) metabolite.

Definition

ChEBI: A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Biological Activity

Fluorimetric reagent and major catecholamine metabolite. Used for fluorimetric determination of oxidative enzymes including glucose oxidase.

storage

+4°C

Homovanillic acid Preparation Products And Raw materials

Raw materials

Guaiacol Palladium Sodium hydroxide Glyoxylic acid Sulfuric acid

Preparation Products

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View Lastest Price from Homovanillic acid manufacturers

Hebei Mujin Biotechnology Co.,Ltd

Product: Chromic sulfate 306-08-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-16

Shanghai Standard Technology Co., Ltd.

Product: Homovanillic acid 306-08-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: Homovanillic acid 306-08-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

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homovanillicaci

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Homovanillic acid 306-08-1

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13C,2H3]-Homovanillic acid

4-Hydroxy-3-methoxyphenylacetic acid in methanol

Homovanillic Acid in Methanol

306-08-1

HOC6H3OCH3CH2CO2H

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