(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

Product Name: (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
CAS No.: 179686-45-4
Chemical Name: (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
Synonyms: N-2-BOC-AMINOCAPROLACTAM;3-N-BOC-AMINO-2-AZEPANONE;3-(Boc-amino)-2-azepanone;3-N-Boc-AMino-epsilon-caprolactaM;tert-butyl 2-oxoazepan-3-ylcarbaMate;(+/-)-N--Boc-Amino-epsilon-caprolactam;ert-butylN-(2-oxoazepan-3-yl)carbamate;(+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM;R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM;(+/-)-N-a-Boc-Amino-epsilon-caprolactam
CBNumber: CB7203725
Molecular Formula: C11H20N2O3
Formula Weight: 228.29
MOL File: 179686-45-4.mol

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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Property

Boiling point:: 417.7±34.0 °C(Predicted)
Density: 1.09
storage temp.: 2-8°C(protect from light)
pka: 11.05±0.20(Predicted)
Appearance: White to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N497023
Product name: 3-N-Boc-Amino-epsilon-caprolactam
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 119288
Product name: 3-N-Boc-Amino-epsilon-caprolactam
Purity: 95+%
Packaging: 1g
Price: $270
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0015290
Product name: (2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity: 95.00%
Packaging: 1G
Price: $765.23
Updated: 2021/12/16

Matrix Scientific

Product number: 119288
Product name: 3-N-Boc-Amino-epsilon-caprolactam
Purity: 95+%
Packaging: 5g
Price: $810
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0015290
Product name: (2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity: 95.00%
Packaging: 2.5G
Price: $1065.66
Updated: 2021/12/16

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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Chemical Properties,Usage,Production

Synthesis

24424-99-5

28957-33-7

179686-45-4

Example 2 Preparation of 3-(S)-tert-butoxycarbonylamino-4,5,6,7-tetrahydroacridoheptan-2-one (4): di-tert-butyl dicarbonate (25.5 g, 0.11 mol) was slowly added to a stirring solution of L-α-amino-ε-caprolactam (compound 3) (15 g, 0.11 mol) and potassium carbonate (26.7 g, 0.11 mol) in a solution of tetrahydrofuran (THF). Once the addition was complete, the reaction mixture was gradually warmed to room temperature and the reaction was continued with stirring for 18 hours. After completion of the reaction, the insoluble solids were removed by filtration and the filtrate was concentrated under reduced pressure to remove the solvent to afford 26.4 g (99% yield) of 3-N-Boc-aminoazepan-2-one (4) as a white solid. Thin layer chromatography (TLC) showed an Rf value of 0.91 (unfolding agent: hexane-ethyl acetate, 9:1). Mass spectrometry (electrospray) showed a molecular ion peak m/z 229 ([M+H]+). Nuclear magnetic resonance hydrogen spectrum (1H-NMR, CDCl3) δ: 1.39 (m, 2H), 1.50 (s, 9H), 1.82 (m, 2H), 2.03 (m, 2H), 3.25 (m, 2H), 4.29 (m, 1H), 5.91 (s, 1H), 6.36 (s, 1H).

References

[1] Patent: US6534495, 2003, B1
[2] Patent: US6541467, 2003, B1
[3] Patent: US6218365, 2001, B1

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Suppliers

China 54 Germany 2 India 1 Switzerland 1 United Kingdom 4 United States 9 Global 71

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179686-45-4, (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAMRelated Search:

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid AKOS 90268 (R)-3-(BOC-AMINO)-2-OXO-1-AZEPINE-ACETIC ACID (S)-3-(BOC-AMINO)-2-OXO-1-AZEPINE-ACETIC ACID AKOS 90229 L(-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM AKOS 90230 AKOS 90036 (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

3-N-Boc-AMino-epsilon-caprolactaM

N-(Hexahydro-2-oxo-1H-azepin-3-yl)carbamic acid tert-butyl ester

(+/-)-N-Alpha-Boc-AMino-Epsilon-CaprolaCLaM

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

N-2-BOC-AMINOCAPROLACTAM

(RS)-N-BOC-ALPHA-AMINO-EPSILON-CAPROLACTAME

(+/-)-N--Boc-Amino-epsilon-caprolactam

(+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM

Carbamic acid, N-(hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester

tert-butyl 2-oxoazepan-3-ylcarbaMate

tert-butyl N-(2-oxoazepan-3-yl)carbamate

R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

Carbamic acid, (hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester

3-N-BOC-AMINO-2-AZEPANONE

(+/-)-(2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER

3-(Boc-amino)-2-azepanone

ert-butylN-(2-oxoazepan-3-yl)carbamate

Hydrazinecarbothioamide,N-(6-methoxyphenyl)-

3-tert-butyloxyamide nitrogen-containing heterocyclic heptane

2-Methyl-2-propanyl (2-oxo-3-azepanyl)carbamate

(+/-)-N-a-Boc-Amino-epsilon-caprolactam

tert-butyl N-(2-oxoazepan-3-yl)carbamate - [B83796]

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

179686-45-4