ChemicalBook > CAS DataBase List > (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

Product Name
(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
CAS No.
179686-45-4
Chemical Name
(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
Synonyms
N-2-BOC-AMINOCAPROLACTAM;3-N-BOC-AMINO-2-AZEPANONE;3-(Boc-amino)-2-azepanone;3-N-Boc-AMino-epsilon-caprolactaM;tert-butyl 2-oxoazepan-3-ylcarbaMate;(+/-)-N--Boc-Amino-epsilon-caprolactam;ert-butylN-(2-oxoazepan-3-yl)carbamate;(+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM;R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM;(+/-)-N-a-Boc-Amino-epsilon-caprolactam
CBNumber
CB7203725
Molecular Formula
C11H20N2O3
Formula Weight
228.29
MOL File
179686-45-4.mol
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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Property

Boiling point:
417.7±34.0 °C(Predicted)
Density 
1.09
storage temp. 
2-8°C(protect from light)
pka
11.05±0.20(Predicted)
Appearance
White to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N497023
Product name
3-N-Boc-Amino-epsilon-caprolactam
Packaging
50mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0015290
Product name
(2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
95.00%
Packaging
1G
Price
$765.23
Updated
2021/12/16
Matrix Scientific
Product number
119288
Product name
3-N-Boc-Amino-epsilon-caprolactam
Purity
95+%
Packaging
5g
Price
$810
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0015290
Product name
(2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
95.00%
Packaging
2.5G
Price
$1065.66
Updated
2021/12/16
Matrix Scientific
Product number
119288
Product name
3-N-Boc-Amino-epsilon-caprolactam
Purity
95+%
Packaging
1g
Price
$270
Updated
2021/12/16
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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Chemical Properties,Usage,Production

Synthesis

24424-99-5

28957-33-7

179686-45-4

Example 2 Preparation of 3-(S)-tert-butoxycarbonylamino-4,5,6,7-tetrahydroacridoheptan-2-one (4): di-tert-butyl dicarbonate (25.5 g, 0.11 mol) was slowly added to a stirring solution of L-α-amino-ε-caprolactam (compound 3) (15 g, 0.11 mol) and potassium carbonate (26.7 g, 0.11 mol) in a solution of tetrahydrofuran (THF). Once the addition was complete, the reaction mixture was gradually warmed to room temperature and the reaction was continued with stirring for 18 hours. After completion of the reaction, the insoluble solids were removed by filtration and the filtrate was concentrated under reduced pressure to remove the solvent to afford 26.4 g (99% yield) of 3-N-Boc-aminoazepan-2-one (4) as a white solid. Thin layer chromatography (TLC) showed an Rf value of 0.91 (unfolding agent: hexane-ethyl acetate, 9:1). Mass spectrometry (electrospray) showed a molecular ion peak m/z 229 ([M+H]+). Nuclear magnetic resonance hydrogen spectrum (1H-NMR, CDCl3) δ: 1.39 (m, 2H), 1.50 (s, 9H), 1.82 (m, 2H), 2.03 (m, 2H), 3.25 (m, 2H), 4.29 (m, 1H), 5.91 (s, 1H), 6.36 (s, 1H).

References

[1] Patent: US6534495, 2003, B1
[2] Patent: US6541467, 2003, B1
[3] Patent: US6218365, 2001, B1

(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM Suppliers

China 54 Germany 2 India 1 Switzerland 1 United Kingdom 4 United States 9 Global 71
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75

179686-45-4, (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAMRelated Search:

(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid AKOS 90268 (R)-3-(BOC-AMINO)-2-OXO-1-AZEPINE-ACETIC ACID (S)-3-(BOC-AMINO)-2-OXO-1-AZEPINE-ACETIC ACID AKOS 90229 L(-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM AKOS 90230 AKOS 90036 (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM

  • 3-N-Boc-AMino-epsilon-caprolactaM
  • N-(Hexahydro-2-oxo-1H-azepin-3-yl)carbamic acid tert-butyl ester
  • (+/-)-N-Alpha-Boc-AMino-Epsilon-CaprolaCLaM
  • (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
  • N-2-BOC-AMINOCAPROLACTAM
  • (RS)-N-BOC-ALPHA-AMINO-EPSILON-CAPROLACTAME
  • (+/-)-N--Boc-Amino-epsilon-caprolactam
  • (+/-)-N-A-BOC-AMINO-EPSILON-CAPROLACTAM
  • Carbamic acid, N-(hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester
  • tert-butyl 2-oxoazepan-3-ylcarbaMate
  • tert-butyl N-(2-oxoazepan-3-yl)carbamate
  • R-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
  • Carbamic acid, (hexahydro-2-oxo-1H-azepin-3-yl)-, 1,1-dimethylethyl ester
  • 3-N-BOC-AMINO-2-AZEPANONE
  • (+/-)-(2-OXO-AZEPAN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
  • 3-(Boc-amino)-2-azepanone
  • ert-butylN-(2-oxoazepan-3-yl)carbamate
  • Hydrazinecarbothioamide,N-(6-methoxyphenyl)-
  • 3-tert-butyloxyamide nitrogen-containing heterocyclic heptane
  • 2-Methyl-2-propanyl (2-oxo-3-azepanyl)carbamate
  • (+/-)-N-a-Boc-Amino-epsilon-caprolactam
  • tert-butyl N-(2-oxoazepan-3-yl)carbamate - [B83796]
  • (+/-)-N-ALPHA-BOC-AMINO-EPSILON-CAPROLACTAM
  • 179686-45-4