ChemicalBook > CAS DataBase List > 1-Boc-4-bromopyrazole
1-Boc-4-bromopyrazole
- Product Name
- 1-Boc-4-bromopyrazole
- CAS No.
- 1150271-23-0
- Chemical Name
- 1-Boc-4-bromopyrazole
- Synonyms
- 1-Boc-4-bromopyrazole;N-Boc-4-broMopyrazole;1-
Boc- 4- bromopyrazole;tert-butyl 4-bromopyrazole-1-carboxylate;t-Butyl 4-bromo-1H-pyrazole-1-carboxylate;tert-Butyl 4-bromo-1H-pyrazol-1-carboxylate;1H-Pyrazole-1-carboxylic acid, 4-bromo-, 1,1-dimethylethyl ester - CBNumber
- CB72101292
- Molecular Formula
- C8H11BrN2O2
- Formula Weight
- 247.09
- MOL File
- 1150271-23-0.mol
More
Less
1-Boc-4-bromopyrazole Property
- Melting point:
- 48-52 °C
- Boiling point:
- 288.7±32.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- -3.17±0.12(Predicted)
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C8H11BrN2O2/c1-8(2,3)13-7(12)11-5-6(9)4-10-11/h4-5H,1-3H3
- InChIKey
- IQEFCRDQVLIADR-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)C=C(Br)C=N1
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 694266
- Product name
- 1-Boc-4-bromopyrazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $127
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 694266
- Product name
- 1-Boc-4-bromopyrazole
- Purity
- 97%
- Packaging
- 10g
- Price
- $603
- Updated
- 2023/06/20
TRC
- Product number
- B201143
- Product name
- 1-BOC-4-bromopyrazole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
Usbiological
- Product number
- 408958
- Product name
- 1-BOC-4-bromopyrazole
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
TRC
- Product number
- B201143
- Product name
- 1-BOC-4-bromopyrazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
More
Less
1-Boc-4-bromopyrazole Chemical Properties,Usage,Production
Synthesis
2075-45-8
24424-99-5
1150271-23-0
Step 1: Preparation of tert-butyl 4-bromo-1H-pyrazole-1-carboxylate Di-tert-butyl dicarbonate (Boc2O, 2.34 mL, 10.2 mmol) was slowly added to a solution of 4-bromo-1H-pyrazole (1 g, 6.8 mmol) in acetonitrile (20 mL) at 0 °C. Subsequently, triethylamine (3.3 mL, 23.8 mmol) and 4-dimethylaminopyridine (DMAP, 0.166 g, 1.36 mmol) were added sequentially to the reaction mixture. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the reaction mixture was diluted with water and extracted with ethyl acetate (100 mL × 3). The organic phases were combined, washed sequentially with water (100 mL) and saturated saline (100 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography (eluent: 10% ethyl acetate/hexane) to afford tert-butyl 4-bromo-1H-pyrazole-1-carboxylate (1.65 g, 98% yield) as a colorless liquid. 1H NMR (400 MHz, CDCl3) δ 8.09 (s, 1H), 7.66 (s, 1H), 1.65 (s, 9H).
References
[1] Patent: WO2016/49165, 2016, A1. Location in patent: Paragraph 00161
[2] Patent: WO2018/172250, 2018, A1. Location in patent: Page/Page column 300
[3] Patent: CN106188116, 2016, A. Location in patent: Paragraph 0016
[4] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 142
[5] Arkivoc, 2014, vol. 2014, # 6, p. 54 - 71
1-Boc-4-bromopyrazole Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
1-Boc-4-bromopyrazole Suppliers
- Tel
- 13477084141; 13477084141
- Fax
- +86(27)65566697
- sales@luohuapharm.com
- Country
- China
- ProdList
- 468
- Advantage
- 60
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 025-58395930
- Fax
- 025-5861-9182
- sales@acornpharma.com
- Country
- China
- ProdList
- 982
- Advantage
- 60
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
- Country
- China
- ProdList
- 1876
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 020-82185713,82185709 13418171485
- Fax
- 020-82185696
- sales@chem-stone.com
- Country
- China
- ProdList
- 744
- Advantage
- 56
- Tel
- 18939837085
- Fax
- 2880152141(QQ)
- youchemicals@gmail.com
- Country
- China
- ProdList
- 1839
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 025-025-52700520 18914499889
- Fax
- 025-52700520
- sales@yfbiotech.com
- Country
- China
- ProdList
- 495
- Advantage
- 58
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 027-67849912
- Fax
- 027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 9148
- Advantage
- 60
- Tel
- 0371-53778726 18003825608
- Fax
- QQ：2885354392
- liuxiaoyan@alfachem.cn
- Country
- China
- ProdList
- 1987
- Advantage
- 58
- Tel
- 025-57043319 15261831516
- Fax
- 025-57043319
- 307514552@qq.com
- Country
- China
- ProdList
- 251
- Advantage
- 50
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 15902830537
- zhanghao@happysyn.com
- Country
- China
- ProdList
- 3180
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-66096098 3165145969
- Fax
- QQ3165145969
- sales@accoronpharm.com
- Country
- China
- ProdList
- 3924
- Advantage
- 55
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9976
- Advantage
- 55
- Tel
- 19906241957
- Fax
- -
- 1557216087@qq.com
- Country
- China
- ProdList
- 1837
- Advantage
- 55
- Tel
- 0411-0411-00000000 13644282108
- Fax
- -
- 3500508746@qq.com
- Country
- China
- ProdList
- 2896
- Advantage
- 55
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- 0539-6362799 20）
- Fax
- 0539-6362799（To 20）
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 021-000000
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9853
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 021-33758897
- sales@scochem.com
- Country
- China
- ProdList
- 1596
- Advantage
- 58
- Tel
- 025-58859352 13155353615
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15525
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- +86-0917-3909592 +86-13892490616
- Fax
- 09173909592
- gksales1@gk-bio.com
- Country
- China
- ProdList
- 9209
- Advantage
- 58
- Tel
- +8615056975894
- Fax
- 86-0551-62678551
- shawn@hirisunpharm.com
- Country
- CHINA
- ProdList
- 9911
- Advantage
- 58
- Tel
- 15901914505 15901914505;
- Fax
- 021-54389085
- 3187892335@qq.com
- Country
- China
- ProdList
- 9889
- Advantage
- 58
- Tel
- 027-67849912
- sales@chemwish.com
- Country
- CHINA
- ProdList
- 10821
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- 650-6922368
- sales@achemblock.com
- Country
- China
- ProdList
- 2992
- Advantage
- 58
- Tel
- 15002184385 15021598081 15002184385
- product001@xiushipharm.com
- Country
- China
- ProdList
- 4719
- Advantage
- 58
- Tel
- 0574-87314919 057487319282
- info@nbinno.com
- Country
- China
- ProdList
- 7047
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
More
Less
View Lastest Price from 1-Boc-4-bromopyrazole manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Boc-4-bromopyrazole 1150271-23-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Boc-4-bromopyrazole 1150271-23-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
Career Henan Chemical Co
- Product
- 1-Boc-4-bromopyrazole 1150271-23-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-02
1150271-23-0, 1-Boc-4-bromopyrazoleRelated Search:
tert-Butyl 1H-pyrazole-1-carboxylate
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline
t-Butyl 4-bromo-1-naphthalenecarboxylate
4-Bromopyrazole