ethyl 4-aminopyrimidine-5-carboxylate

Product Name: ethyl 4-aminopyrimidine-5-carboxylate
CAS No.: 65195-35-9
Chemical Name: ethyl 4-aminopyrimidine-5-carboxylate
Synonyms: ethyl 4-aminopyrimidine-5-carboxylate;4-AMinopyriMidine-5-carboxylic Acid Ethyl Ester;5-Pyrimidinecarboxylic acid, 4-amino-, ethyl ester;ethyl 4-aminopyrimidine-5-carboxylate ISO 9001：2015 REACH
CBNumber: CB72123858
Molecular Formula: C7H9N3O2
Formula Weight: 167.17
MOL File: 65195-35-9.mol

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ethyl 4-aminopyrimidine-5-carboxylate Property

Melting point:: 174-177 °C
Boiling point:: 304.0±22.0 °C(Predicted)
Density: 1.261±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Methanol/Water; DMF, DMSO
form: Solids
pka: 3.94±0.10(Predicted)
color: Off-White

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A629105
Product name: 4-Aminopyrimidine-5-carboxylicAcidEthylEster
Packaging: 250mg
Price: $580
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 43397
Product name: 4-Aminopyrimidine-5-carboxylicAcidEthylEster
Packaging: 250mg
Price: $1025
Updated: 2021/12/16

AK Scientific

Product number: 9978AB
Product name: Ethyl4-aminopyrimidine-5-carboxylate
Packaging: 25g
Price: $1453
Updated: 2021/12/16

Matrix Scientific

Product number: 114694
Product name: Ethyl 4-aminopyrimidine-5-carboxylate
Purity: 97%
Packaging: 1g
Price: $480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0311681
Product name: 4-AMINO-5-PYRIMIDINECARBOXYLIC ACID ETHYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $503.49
Updated: 2021/12/16

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ethyl 4-aminopyrimidine-5-carboxylate Chemical Properties,Usage,Production

Uses

4-Aminopyrimidine-5-carboxylic Acid Ethyl Ester is a substituted pyrimidine and an intermediate in the synthesis of Thiamine (T344185) analogues.

Synthesis

20737-41-1

64-17-5

65195-35-9

4-Aminopyrimidine-5-carboxylic acid (1.0 g, 7.2 mmol) was used as raw material and mixed with 15 mL of ethanol and 1 mL of concentrated sulfuric acid. The suspension was stirred under reflux conditions for 72 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was poured on ice and stirred for 1 hour and subsequently neutralized with saturated sodium carbonate solution. The product was extracted with chloroform (3 x 70 mL) and the combined organic layers were washed with brine and dried with anhydrous sodium sulfate. Finally, the organic phase was concentrated under reduced pressure to give ethyl 4-aminopyrimidine-5-carboxylate (0.76 g, 63% yield).

References

[1] Patent: US2007/179164, 2007, A1. Location in patent: Page/Page column 46
[2] Patent: US9486455, 2016, B2. Location in patent: Page/Page column `46

ethyl 4-aminopyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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ethyl 4-aminopyrimidine-5-carboxylate Suppliers

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View Lastest Price from ethyl 4-aminopyrimidine-5-carboxylate manufacturers

Dideu Industries Group Limited

Product: ethyl 4-aminopyrimidine-5-carboxylate 65195-35-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-13

Career Henan Chemical Co

Product: ethyl 4-aminopyrimidine-5-carboxylate 65195-35-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

Career Henan Chemical Co

Product: ethyl 4-aminopyrimidine-5-carboxylate 65195-35-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

65195-35-9, ethyl 4-aminopyrimidine-5-carboxylateRelated Search:

Ethyl 4-amino-2-(ethylthio)-5-pyrimidinecarboxylate ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE ETHYL 4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBOXYLATE Ethyl 4-amino-2-hydroxypyrimidine-5-carboxylate ETHYL 2-(METHYLSULFANYL)-4-PIPERIDINO-5-PYRIMIDINECARBOXYLATE ETHYL 4-(METHYLAMINO)-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE ETHYL 4-(BENZYLAMINO)-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE {[4-AMINO-5-(ETHOXYCARBONYL)PYRIMIDIN-2-YL]THIO}ACETIC ACID ETHYL 4-MORPHOLINO-2-PHENYL-5-PYRIMIDINECARBOXYLATE RARECHEM AL FH 0049 RARECHEM AL FB 0074 ETHYL 4-(2-[(2,6-DICHLORO-4-PYRIDYL)CARBONYL]HYDRAZINO)-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE BUTTPARK 21\09-28 ETHYL 4-(DIMETHYLAMINO)-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE ETHYL 2,4-DIAMINO-6-METHYLPYRIMIDINE-5-CARBOXYLATE ETHYL 4-(BENZYLAMINO)-2-PHENYL-5-PYRIMIDINECARBOXYLATE RARECHEM AL FF 0030 BUTTPARK 21\09-21

ethyl 4-aminopyrimidine-5-carboxylate

4-AMinopyriMidine-5-carboxylic Acid Ethyl Ester

5-Pyrimidinecarboxylic acid, 4-amino-, ethyl ester

ethyl 4-aminopyrimidine-5-carboxylate ISO 9001：2015 REACH

65195-35-9