D,L-Tryptophan Methyl Ester Hydrochloride
- Product Name
- D,L-Tryptophan Methyl Ester Hydrochloride
- CAS No.
- 5619-09-0
- Chemical Name
- D,L-Tryptophan Methyl Ester Hydrochloride
- Synonyms
- NSC 34498;H-DL-Trp-OMe;DL-Trp-OMe·HCl;H-DL-TRP-OME HCL;TIMTEC-BB SBB003122;DL-TRYPTOPHAN-OME HCL;DL-TRYPTOPHAN METHYL ESTER HCL;DL-Tryptophan Methyl ester hydrochlorede;DL-TRYPTOPHAN METHYL ESTER HYDROCHLORIDE;DL-Methyl Tryptophanate Monohydrochloride
- CBNumber
- CB7214907
- Molecular Formula
- C12H15ClN2O2
- Formula Weight
- 254.71
- MOL File
- 5619-09-0.mol
D,L-Tryptophan Methyl Ester Hydrochloride Property
- Melting point:
- 221-222
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Methanol, Water
- form
- Solid
- color
- Off-white to white
- InChI
- InChI=1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H
- InChIKey
- XNFNGGQRDXFYMM-UHFFFAOYSA-N
- SMILES
- C12C=CC=CC=1NC=C2CC(N)C(=O)OC.Cl
- CAS DataBase Reference
- 5619-09-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Hazard Note
- Irritant
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 290494
- Product name
- D,L-Tryptophan methyl ester hydrochloride
- Packaging
- 1g
- Price
- $287
- Updated
- 2021/12/16
- Product number
- T9020-30
- Product name
- D,L-Tryptophan Methyl Ester, Hydrochloride
- Packaging
- 10g
- Price
- $403
- Updated
- 2021/12/16
- Product number
- T895000
- Product name
- D,L-TryptophanMethylEsterHydrochloride
- Packaging
- 5g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- AS25766
- Product name
- DL-Tryptophan Methyl Ester Hydrochloride
- Purity
- 97+%
- Packaging
- 25g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- 4H58-1-Y1
- Product name
- DL-Tryptophan methyl ester hydrochloride
- Purity
- 97%
- Packaging
- 25g
- Price
- $96
- Updated
- 2021/12/16
D,L-Tryptophan Methyl Ester Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
Amino acid derivative that may be used to prepare the corresponding amino acid amide L-Tryptophanamide Hydrochloride (Cat. #T89550).
Uses
Amino acid derivative， D,L-Tryptophan Methyl Ester Hydrochloride may be used to prepare the corresponding amino acid amide L-Tryptophanamide Hydrochloride (Cat. #T89550)
Synthesis
67-56-1
73-22-3
7524-52-9
The general procedure for the synthesis of L-tryptophan methyl ester hydrochloride from methanol and L-tryptophan was as follows: L-tryptophan (18.2 mmol) was dissolved in methanol (20 mL) at 0 °C with stirring. Thionyl chloride (1.6 mL, 22 mmol) was added slowly and dropwise over 10 min. Subsequently, the reaction mixture was gradually warmed to room temperature and heated under reflux conditions for 3 hours. Upon completion of the reaction, the solvent and volatiles were removed by distillation under reduced pressure. The resulting product was ground with ethyl acetate to give L-tryptophan methyl ester hydrochloride as a colorless solid in 100% yield. The product was a white solid with a yield of 4.63 g. Its 1H NMR (400 MHz, CD3OD) and 13C NMR (100 MHz, CD3OD) data were consistent with those reported in the literature, confirming the structure and purity of the product.
References
[1] Tetrahedron, 2001, vol. 57, # 51, p. 10181 - 10189
[2] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0111
[3] European Journal of Medicinal Chemistry, 2016, vol. 114, p. 318 - 327
[4] New Journal of Chemistry, 2018, vol. 42, # 16, p. 13549 - 13557
[5] Organic and Biomolecular Chemistry, 2014, vol. 12, # 41, p. 8280 - 8287
D,L-Tryptophan Methyl Ester Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D,L-Tryptophan Methyl Ester Hydrochloride manufacturers
- Product
- DL-Trp-Ome.HCl 5619-09-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-04-09
- Product
- D,L-Tryptophan Methyl Ester Hydrochloride 5619-09-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08