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UNOPROSTONE

Product Name
UNOPROSTONE
CAS No.
120373-36-6
Chemical Name
UNOPROSTONE
Synonyms
UNOPROSTONE;Unii-6X4F561V3w;Unoprostone [inn];Emorfazone Impurity 6;Alprostadil Impurity 20;13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA;9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
CBNumber
CB7220472
Molecular Formula
C22H38O5
Formula Weight
382.53
MOL File
120373-36-6.mol
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UNOPROSTONE Property

Boiling point:
562.9±40.0 °C(Predicted)
Density 
1.069±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml
pka
4.76±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
5mg
Price
$264
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
10mg
Price
$468
Updated
2024/03/01
Cayman Chemical
Product number
16680
Product name
Unoprostone
Purity
≥98%
Packaging
50mg
Price
$1862
Updated
2024/03/01
TRC
Product number
U847060
Product name
Unoprostane
Packaging
5mg
Price
$210
Updated
2021/12/16
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UNOPROSTONE Chemical Properties,Usage,Production

Uses

Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.

Definition

ChEBI: Unoprostone is an oxo monocarboxylic acid, a prostaglandins Falpha and a ketone. It has a role as an antiglaucoma drug and an antihypertensive agent.

General Description

Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.

UNOPROSTONE Preparation Products And Raw materials

Raw materials

Preparation Products

120373-36-6, UNOPROSTONERelated Search:


  • UNOPROSTONE
  • 9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID
  • Unii-6X4F561V3w
  • Unoprostone [inn]
  • 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA
  • (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
  • Alprostadil Impurity 20
  • Emorfazone Impurity 6
  • 120373-36-6