Cyclo(L-Pro-L-Trp-)

Product Name: Cyclo(L-Pro-L-Trp-)
CAS No.: 38136-70-8
Chemical Name: Cyclo(L-Pro-L-Trp-)
Synonyms: Brevianamide F;Cyclo(-Trp-Pro);Cyclo(L-Trp-L-Pro-);Cyclo(L-Pro-L-Trp-);Eptifibatide Impurity 11;Cyclo-L-tryptophyl-L-proline;L-Prolyl-L-tryptophan anhydride;Trp-Pro-diketopiperazine Eptifibatide;(3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;(3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber: CB72232479
Molecular Formula: C16H17N3O2
Formula Weight: 283.33
MOL File: 38136-70-8.mol

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Cyclo(L-Pro-L-Trp-) Property

Melting point:: 165-167 °C
Boiling point:: 633.2±48.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 13.20±0.40(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3432
Product name: Brevianamide F
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $63.2
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML3432
Product name: Brevianamide F
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $255
Updated: 2023/06/20

Cayman Chemical

Product number: 23493
Product name: Brevianamide F
Purity: ≥98%
Packaging: 5mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 23493
Product name: Brevianamide F
Purity: ≥98%
Packaging: 10mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 23493
Product name: Brevianamide F
Purity: ≥98%
Packaging: 25mg
Price: $176
Updated: 2024/03/01

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Cyclo(L-Pro-L-Trp-) Chemical Properties,Usage,Production

Description

Brevianamide F is an alkaloid metabolite produced by various Streptomyces, Actinomycetes, and Aspergillus strains that has diverse biological activities. It inhibits growth of M. luteus and S. aureus in an inhibitory disc assay when used at a concentration of 30 μg/disc as well as the Bacille Calmette-Guerin M. bovis strain (MIC = 12.5 μg/ml). Brevianamide F has antifouling activity, inhibiting attachment of B. neritina larvae to PVC plates without inducing lethality (EC₅₀ = 6.35 μg/ml; LC₅₀ = >200 μg/ml in paint used to coat PVC plates).

Uses

Brevianamide F is used in the preparation, reactions, medicinal and cheical propreties of diketopiperazines as bioactive natural products. Acts as a reagent in the total synthesis and antitumor activity in vitro of glioperazine C and its derivatives, synthesis and biological evaluation of a post-synthetically trp-based diketopiperazine and it’s antitumor structure-activity relationship.

Definition

ChEBI: A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tr ptophan and L-proline).

Cyclo(L-Pro-L-Trp-) Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclo(L-Pro-L-Trp-) Suppliers

China 63 India 2 United States 8 Global 73

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

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BioBioPha Co., Ltd.

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Sichuan Wei Keqi Biological Technology Co., Ltd.

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ShangHai Siyan Biological Technology Co., Ltd.

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Shanghai Chaolan Chemical Technology Center

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View Lastest Price from Cyclo(L-Pro-L-Trp-) manufacturers

Career Henan Chemical Co

Product: Cyclo(L-Pro-L-Trp-) 38136-70-8
Price: US $1.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 95%~99%
Supply Ability: per week:100kg
Release date: 2019-09-05

38136-70-8, Cyclo(L-Pro-L-Trp-)Related Search:

L-Aspartic acid, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-, (1→3')-disulfide with L-tryptophyl-L-prolyl-L-cysteinamide (9CI) Eptifibatide impurity 3/Deamidated Eptifibatide Impurity/(3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)Methyl)-17-(carboxymethyl)-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosine-3-carbo L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→1'),(6→6')-bis(disulfide) N-[2-(Phenylmethyl)phenyl]-2-chloroacetamide Acetamide, 2-methoxy-N-[2-(phenylmethyl)phenyl]- Methanone, (2-aminophenyl)phenyl-, hydrazone, (Z)- L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→7)-disulfide (9CI) Benzamide, N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-2-(hydroxymethyl)- 7-Bromo Epinastine Eptifibatide non cyclic impurity 3'-Hydroxyacetophenone 6-Chloromethylmorphanthridine Acetamide, 2-(1-methylethoxy)-N-[2-(phenylmethyl)phenyl]-

(3S)-2,3,6,7,8,8aα-Hexahydro-3β-(1H-indol-3-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione

(3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione

Brevianamide F

Cyclo(L-Pro-L-Trp-)

Cyclo(L-Trp-L-Pro-)

(3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

Cyclo(-Trp-Pro)

Cyclo-L-tryptophyl-L-proline

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)-

Trp-Pro-diketopiperazine Eptifibatide

Bacterial,Inhibitor,PI3K,Brevianamide F,antibacterial,PI3Kα,inhibit,Phosphoinositide 3-kinase,mycotoxin

Eptifibatide Impurity 11

L-Prolyl-L-tryptophan anhydride

38136-70-8