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Cyclo(L-Pro-L-Trp-)

Product Name
Cyclo(L-Pro-L-Trp-)
CAS No.
38136-70-8
Chemical Name
Cyclo(L-Pro-L-Trp-)
Synonyms
Brevianamide F;Cyclo(-Trp-Pro);Cyclo(L-Trp-L-Pro-);Cyclo(L-Pro-L-Trp-);Eptifibatide Impurity 11;Cyclo-L-tryptophyl-L-proline;L-Prolyl-L-tryptophan anhydride;Trp-Pro-diketopiperazine Eptifibatide;(3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE;(3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber
CB72232479
Molecular Formula
C16H17N3O2
Formula Weight
283.33
MOL File
38136-70-8.mol
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Cyclo(L-Pro-L-Trp-) Property

Melting point:
165-167 °C
Boiling point:
633.2±48.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.20±0.40(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3432
Product name
Brevianamide F
Purity
≥98% (HPLC)
Packaging
5MG
Price
$63.2
Updated
2023/06/20
Sigma-Aldrich
Product number
SML3432
Product name
Brevianamide F
Purity
≥98% (HPLC)
Packaging
25MG
Price
$255
Updated
2023/06/20
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
10mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
23493
Product name
Brevianamide F
Purity
≥98%
Packaging
25mg
Price
$176
Updated
2024/03/01
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Cyclo(L-Pro-L-Trp-) Chemical Properties,Usage,Production

Description

Brevianamide F is an alkaloid metabolite produced by various Streptomyces, Actinomycetes, and Aspergillus strains that has diverse biological activities. It inhibits growth of M. luteus and S. aureus in an inhibitory disc assay when used at a concentration of 30 μg/disc as well as the Bacille Calmette-Guerin M. bovis strain (MIC = 12.5 μg/ml). Brevianamide F has antifouling activity, inhibiting attachment of B. neritina larvae to PVC plates without inducing lethality (EC50 = 6.35 μg/ml; LC50 = >200 μg/ml in paint used to coat PVC plates).

Uses

Brevianamide F is used in the preparation, reactions, medicinal and cheical propreties of diketopiperazines as bioactive natural products. Acts as a reagent in the total synthesis and antitumor activity in vitro of glioperazine C and its derivatives, synthesis and biological evaluation of a post-synthetically trp-based diketopiperazine and it’s antitumor structure-activity relationship.

Definition

ChEBI: A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tr ptophan and L-proline).

Cyclo(L-Pro-L-Trp-) Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyclo(L-Pro-L-Trp-) Suppliers

Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6445
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7045
Advantage
58
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View Lastest Price from Cyclo(L-Pro-L-Trp-) manufacturers

Career Henan Chemical Co
Product
Cyclo(L-Pro-L-Trp-) 38136-70-8
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
95%~99%
Supply Ability
per week:100kg
Release date
2019-09-05

38136-70-8, Cyclo(L-Pro-L-Trp-)Related Search:


  • (3S)-2,3,6,7,8,8aα-Hexahydro-3β-(1H-indol-3-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione
  • (3S,8aα)-3β-(1H-Indole-3-ylmethyl)octahydropyrrolo[1,2-a]pyrazine-1,4-dione
  • Brevianamide F
  • Cyclo(L-Pro-L-Trp-)
  • Cyclo(L-Trp-L-Pro-)
  • (3S,8AS)-3-(1H-INDOL-3-YLMETHYL)HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE
  • Cyclo(-Trp-Pro)
  • Cyclo-L-tryptophyl-L-proline
  • Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)-
  • Trp-Pro-diketopiperazine Eptifibatide
  • Bacterial,Inhibitor,PI3K,Brevianamide F,antibacterial,PI3Kα,inhibit,Phosphoinositide 3-kinase,mycotoxin
  • Eptifibatide Impurity 11
  • L-Prolyl-L-tryptophan anhydride
  • 38136-70-8