CALMIDAZOLIUM CHLORIDE
- Product Name
- CALMIDAZOLIUM CHLORIDE
- CAS No.
- 94724-12-6
- Chemical Name
- CALMIDAZOLIUM CHLORIDE
- Synonyms
- R 24571;CALMIDAZOLIUM;COMPOUND 48/80;COMPOUND R24571;R 24571 CHLORIDE;CALMIDAZOLIUM CHLORIDE;CALMODULIN INHIBITOR R 24571;COMPOUND 48/80 TRIHYDROCHLORIDE;Poly-p-methoxyphenethylmethylamine;Compound 48/80 trihydrochloride, G protein activator
- CBNumber
- CB7231629
- Molecular Formula
- C32H45N3O3
- Formula Weight
- 519.72
- MOL File
- 94724-12-6.mol
CALMIDAZOLIUM CHLORIDE Property
- Boiling point:
- 630.9±50.0 °C(Predicted)
- Density
- 1.050±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: 50 mg/mL
- pka
- 10.81±0.10(Predicted)
- form
- solid
- color
- white
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25
- Safety Statements
- 22-24/25-45-36/37
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- F
- 3-8-10
CALMIDAZOLIUM CHLORIDE Chemical Properties,Usage,Production
Uses
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2].
References
[1] Schemann M, et al. The mast cell degranulator compound 48/80 directly activates neurons. PLoS One. 2012;7(12):e52104. DOI:10.1371/journal.pone.0052104
[2] Wang YH, Taché Y, Harris AG, Kreutner W, Daly AF, Wei JY. Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. Allergy. 2005;60(1):117-124. DOI:10.1111/j.1398-9995.2004.00641.x
[3] Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. J Cell Physiol. 1984;119(1):1-6. DOI:10.1002/jcp.1041190102
CALMIDAZOLIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
CALMIDAZOLIUM CHLORIDE Suppliers
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29784
- Advantage
- 58
- Tel
- 025-025-66113011 18626450290
- cb5@aikonchem.com
- Country
- China
- ProdList
- 10358
- Advantage
- 58
- Tel
- 400-6206333 13167063860
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 48457
- Advantage
- 58
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- 021-60936350
- scbt@scbt.com
- Country
- China
- ProdList
- 6594
- Advantage
- 58