ChemicalBook > CAS DataBase List > KIFUNENSINE

KIFUNENSINE

Product Name
KIFUNENSINE
CAS No.
109944-15-2
Chemical Name
KIFUNENSINE
Synonyms
FR 900494;Kifunensin;KIFUNENSINE;Kifunensine min. 99%;[5R-(5α,6β,7α,8α,8aα)]-;Kifunensine, (+)- - FR 900494;KIFUNENSINE, KITASATOSPORIA KIFUNENSE;Kifunensine, Kitasatosporia kifunense - CAS 109944-15-2 - Calbiochem;Hexahydro-6R,7S,8aS-trihydroxy-5R-(hydroxymethyl)-imidazo[1,2-a] pyridine-2,3-dione;(5R,6R,7S,8R,8AS)-6,7,8-trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione
CBNumber
CB7233173
Molecular Formula
C8H12N2O6
Formula Weight
232.19
MOL File
109944-15-2.mol
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KIFUNENSINE Property

Melting point:
>280°C
Density 
1.85±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
water, double-distilled: soluble50MM
form 
White solid
pka
9.61±0.70(Predicted)
Stability:
Desiccate and Store at -20°C
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
K1140
Product name
Kifunensine
Purity
mannosidase inhibitor
Packaging
1mg
Price
$206
Updated
2021/03/22
Sigma-Aldrich
Product number
422500
Product name
Kifunensine
Purity
A potent alkaloid inhibitor of mannosidase I.
Packaging
1mg
Price
$293.22
Updated
2021/03/22
Cayman Chemical
Product number
10009437
Product name
Kifunensine
Purity
≥98%
Packaging
5mg
Price
$293
Updated
2021/03/22
Cayman Chemical
Product number
10009437
Product name
Kifunensine
Purity
≥98%
Packaging
1mg
Price
$65
Updated
2021/03/22
Cayman Chemical
Product number
10009437
Product name
Kifunensine
Purity
≥98%
Packaging
10mg
Price
$488
Updated
2021/03/22
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KIFUNENSINE Chemical Properties,Usage,Production

Chemical Properties

White Powder

Uses

Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme

Biological Activity

Inhibitor of class I α -mannosidases that inhibits glycoprotein processing. Inhibits human endoplasmic reticulum α -1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with K i values of 130 and 23 nM respectively.

KIFUNENSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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KIFUNENSINE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
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50
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9914
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169-
Fax
021-64609160
Email
kewelchemexp@yahoo.com
Country
China
ProdList
9839
Advantage
50
Sigma-Aldrich
Tel
021-61415566- ;
Email
orderCN@merckgroup.com;orderCN@merckgroup.com
Country
China
ProdList
48786
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80
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
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8454
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60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
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400-002-6226
Email
sales@biochemall.cn
Country
China
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54467
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BOC Sciences
Tel
16314854226
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inquiry@bocsci.com
Country
United States
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19673
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11410
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58

109944-15-2, KIFUNENSINERelated Search:


  • Kifunensine, Kitasatosporia kifunense - CAS 109944-15-2 - Calbiochem
  • Kifunensine, (+)- - FR 900494
  • FR 900494, Hexahydro-6R,7S,8aS-trihydroxy-5R-(hydroxymethyl)-imidazo[1,2-a] pyridine-2,3-dione
  • (5R,8aS)-1,5,6,7,8,8a-Hexahydro-6β,7α,8α-trihydroxy-5α-(hydroxymethyl)imidazo[1,2-a]pyridine-2,3-dione
  • (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione
  • [5R-(5α,6β,7α,8α,8aα)]-
  • Kifunensine min. 99%
  • FR 900494
  • Hexahydro-6R,7S,8aS-trihydroxy-5R-(hydroxymethyl)-imidazo[1,2-a] pyridine-2,3-dione
  • (5R,6R,7S,8R,8AS)-6,7,8-trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione
  • KIFUNENSINE
  • KIFUNENSINE, KITASATOSPORIA KIFUNENSE
  • Imidazo1,2-apyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R,6R,7S,8R,8aS)-
  • Kifunensin
  • 109944-15-2
  • C8H12N2O6
  • Antibiotics
  • All Inhibitors
  • Glycosidase Inhibitors
  • Inhibitors